Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | Isoalantolactone | 470-17-7 | Isohelenin | iso-alantolacton | CHEBI:5981 | (+)-Isoalantolactone | (3aR,4aS,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one | (+/-)-Isoalantolactone | QTF89ZHT7V | Isoalantolactone, (+/-)- | BYH07P620U | NSC241036 | NSC-241 |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
Associated Targets(Human)
ESR1 Tclin Estrogen receptor (0 Activities)
NR4A2 Tchem Nuclear receptor subfamily 4 group A member 2 (0 Activities)
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TGFB1 Tbio Transforming growth factor beta-1 proprotein (0 Activities)
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MYB Tbio Transcriptional activator Myb (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ESR1 Tclin Estrogen receptor alpha (17718 Activities)
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BT-20 (503 Activities)
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HT-1080 (3966 Activities)
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K562 (73714 Activities)
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MCF7 (126967 Activities)
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A549 (127892 Activities)
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WiDr (1835 Activities)
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HepG2 (196354 Activities)
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NCI-H460 (60772 Activities)
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HUVEC (11049 Activities)
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NCI-H520 (551 Activities)
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HeLa (62764 Activities)
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NR4A2 Tchem Nuclear receptor subfamily 4 group A member 2 (460 Activities)
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HEK-293T (167025 Activities)
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SMAD3 Tchem Transforming growth factor beta-1 proprotein/Mothers against decapentaplegic homolog 3 (6 Activities)
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SK-N-BE(2) (28 Activities)
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Associated Targets(non-human)
Salmonella typhimurium (15756 Activities)
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Triticum aestivum (1582 Activities)
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Cavia porcellus (23802 Activities)
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Mus musculus (284745 Activities)
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P388 (20296 Activities)
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PC-12 (7051 Activities)
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Aedes atropalpus (23 Activities)
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Sitophilus oryzae (115 Activities)
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MYB Transcriptional activator Myb (118 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (3aR,4aS,8aR,9aR)-8a-methyl-3,5-dimethylidene-3a,4,4a,6,7,8,9,9a-octahydrobenzo[f][1]benzofuran-2-one |
|---|---|
| INCHI | InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h11-13H,1-2,4-8H2,3H3/t11-,12+,13-,15-/m1/s1 |
| InChi Key | CVUANYCQTOGILD-QVHKTLOISA-N |
| Canonical SMILES | CC12CCCC(=C)C1CC3C(C2)OC(=O)C3=C |
| Isomeric SMILES | C[C@]12CCCC(=C)[C@@H]1C[C@H]3[C@@H](C2)OC(=O)C3=C |
| PubChem CID | 73285 |
| Molecular Weight | 232.32 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Specific Rotation[α] | +168 to +178 deg(C=1, CHCl3) |
|---|---|
| Melt Point(°C) | 109.0 to 113.0 °C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H317:May cause an allergic skin reaction |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. |