Basic Description

Synonyms	.alpha.-Methylpropionic acid \| InChI=1/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6 \| 1iup \| STR03465 \| alpha-Methylpropionate \| ISOBUTYRIC ACID \| Iso-butyric acid \| 2-METHYLPROPANOIC ACID [HSDB] \| Isobutanoate \| CHEBI:16135 \| FT-0625068 \| GTPL1060 \| Q415062 \| Ac
Specifications & Purity	Moligand™, for synthesis
Storage Temp	Room temperature
Shipped In	Normal
Grade	for synthesis, Moligand™

Associated Targets(Human)

FFAR2 Tchem Free fatty acid receptor 2 (0 Activities)

Discover Target: FFAR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FFAR3 Tchem Free fatty acid receptor 3 (0 Activities)

Discover Target: FFAR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

K562 (73714 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

HD1 Histone deacetylase (38 Activities)

Discover Target: HD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

S49 (59 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-methylpropanoic acid
INCHI	InChI=1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6)
InChi Key	KQNPFQTWMSNSAP-UHFFFAOYSA-N
Canonical SMILES	CC(C)C(=O)O
Isomeric SMILES	CC(C)C(=O)O
WGK Germany	1
RTECS	NQ4375000
PubChem CID	6590
UN Number	2529
Packing Group	III
Molecular Weight	88.11
Beilstein	635770
Reaxy-Rn	635770

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
J2320344	Certificate of Analysis	Sep 11, 2023	I434199
J2320345	Certificate of Analysis	Sep 11, 2023	I434199
J2320346	Certificate of Analysis	Sep 11, 2023	I434199

Chemical and Physical Properties

Solubility	618g/L
Refractive Index	1.393
Flash Point(°F)	131 °F
Flash Point(°C)	59℃
Boil Point(°C)	154.5°C
Melt Point(°C)	-47°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS05, GHS02
Signal	Danger
Hazard Statements	H311:Toxic in contact with skin H314:Causes severe skin burns and eye damage H302:Harmful if swallowed H402:Harmful to aquatic life H226:Flammable liquid and vapor
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help.
WGK Germany	1
RTECS	NQ4375000
Reaxy-Rn	635770
Class	3, 8
Merck Index	5155

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yunzi Feng, Ziming Xie, Mingtao Huang, Xing Tong, Sha Hou, Hoeseng Tin, Mouming Zhao. (2023) Decoding temperature-driven microbial community changes and flavor regulation mechanism during winter fermentation of soy sauce. FOOD RESEARCH INTERNATIONAL, (113756). [PMID:38225154] [10.1016/j.foodres.2023.113756]
2. Jiachen Ma, Tian Yuan, Yuqi Gao, Xiaoming Zeng, Zhigang Liu, Jinming Gao. (2023) Torreya grandis oil attenuates cognitive impairment in scopolamine-induced mice. Food & Function, 14 (23): (10520-10534). [PMID:37946597] [10.1039/D3FO03800A]
3. Jing Wang, Sheng Ke, Padraig Strappe, Ming Ning, Zhongkai Zhou. (2023) Structurally Orientated Rheological and Gut Microbiota Fermentation Property of Mannans Polysaccharides and Oligosaccharides. Foods, 12 (21): (4002). [PMID:37959121] [10.3390/foods12214002]
4. Dongpeng Wang, Yan Dong, Ying Xie, Yangxin Xiao, Chang Ke, Kun Shi, Zhongshi Zhou, Jiyuan Tu, Linghang Qu, Yanju Liu. (2023) Atractylodes lancea Rhizome Polysaccharide Alleviates Immunosuppression and Intestinal Mucosal Injury in Mice Treated with Cyclophosphamide. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, (1): [PMID:37861444] [10.1021/acs.jafc.3c05173]
5. Yu-Heng Mao, Minghan Wang, Yu Yuan, Jing-Kun Yan, Yanqun Peng, Guoqin Xu, Xiquan Weng. (2023) Konjac Glucomannan Counteracted the Side Effects of Excessive Exercise on Gut Microbiome, Endurance, and Strength in an Overtraining Mice Model. Nutrients, 15 (19): (4206). [PMID:37836491] [10.3390/nu15194206]
6. Jie Xiong, Ya-ying Wang, Muhammad Yousaf, Dong-mei Liu. (2023) Improvement of Physicochemical Properties and Flavor of Pickled Radish through the Use of a Direct-Vat Set Starter Consisting of Lactiplantibacillus Plantarum and Leuconostoc Mesenteroides. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, [PMID:21153684] [10.1111/ijfs.16731]
7. Jing Cheng, Guangwen Zhang, Liu Liu, Jianming Luo, Xichun Peng. (2023) Anti-inflammatory activity of β-glucans from different sources before and after fermentation by fecal bacteria in vitro. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, [PMID:37740718] [10.1002/jsfa.12997]
8. Zuanyuan Huang, Mengwei Hu, Xiuyi Peng, Rui Wang, Xiaoxiao Song, Junyi Yin. (2023) The protective effect of small black soybean (Vigna Mungo L.) polysaccharide on acetic acid-induced gastric ulcer in SD rats and its impact on gut microbiota and metabolites. Food Bioscience, 56 (6): (103187). [PMID:12763021] [10.1016/j.fbio.2023.103187]
9. Taixiang Gao, Hongxiong Zhang, Qinqing Li, Feng Zhao, Nan Wang, Wenbin He, Junlong Zhang, Rui Wang. (2023) Fuzi decoction treats chronic heart failure by regulating the gut microbiota, increasing the short-chain fatty acid levels and improving metabolic disorders. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 236 (2): (115693). [PMID:37696191] [10.1016/j.jpba.2023.115693]
10. Hong Song, Rui Guo, Xianbao Sun, Yuxing Kou, Xuan Ma, Yinan Chen, Lihua Song, Chunmei Yuan, Yan Wu. (2023) Xylooligosaccharides from corn cobs alleviate loperamide-induced constipation in mice via modulation of gut microbiota and SCFA metabolism. Food & Function, [PMID:37694718] [10.1039/D3FO02688D]
11. Qiao Chen-Meng, Zhou Yu, Quan Wei, Ma Xiao-Yu, Zhao Li-Ping, Shi Yun, Hong Hui, Wu Jian, Niu Gu-Yu, Chen Yu-Nuo, Zhu Shan, Cui Chun, Zhao Wei-Jiang, Shen Yan-Qin. (2023) Fecal Microbiota Transplantation from Aged Mice Render Recipient Mice Resistant to MPTP-Induced Nigrostriatal Degeneration Via a Neurogenesis-Dependent but Inflammation-Independent Manner. Neurotherapeutics, (1-22). [PMID:37596429] [10.1007/s13311-023-01420-1]
12. Lu Wang, Zhen Li, Siying An, Huipeng Zhu, Xiaoyu Li, Dawei Gao. (2023) Malus baccata (Linn.) Borkh polyphenols-loaded nanoparticles ameliorate intestinal health by modulating intestinal function and gut microbiota. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, (126233). [PMID:37573904] [10.1016/j.ijbiomac.2023.126233]
13. Xiaojie Geng, Qing Li, Xinlei Wang, Lin Zhu, Bowen Wang, Fuping Zheng, Guangnan Wang, Erbao Chen, Yuhang Zhang. (2023) Environmental factors induced metabolome shifts during Laobaigan-flavor Baijiu fermentation. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 123 (105570). [PMID:] [10.1016/j.jfca.2023.105570]
14. Chen Sun, Bo Liu, Fengzhi Zhou, Qianqian Zheng, Chunmei Dai, Wei Wei, Guochao Liao, Yuqi Sun. (2023) Assessment of Purity, Stability, and Pharmacokinetics of NGP-1, a Novel Prodrug of GS441254 with Potential Anti-SARS-CoV-2 Activity, Using Liquid Chromatography. MOLECULES, 28 (15): (5634). [PMID:37570604] [10.3390/molecules28155634]
15. Huan-Huan Chen, Qi-Jun Wu, Tie-Ning Zhang, Yu-Hong Zhao. (2023) Gut microbiome and serum short-chain fatty acids are associated with responses to chemo- or targeted therapies in Chinese patients with lung cancer. Frontiers in Microbiology, 14 (1165360). [PMID:37564290] [10.3389/fmicb.2023.1165360]
16. Shijin Xiong, Dandan Qiu, Xiaoyan Xu, Tonghao Du, Zhen Peng, Muyan Xiao, Tao Huang, Jinqing Huang, Hongbing Ren, Mingyong Xie, Tao Xiong. (2023) Heterogeneity of microbiome and flavor profiles of industrial-scale Laotan Suancai: Fermentation craft plays important roles. Food Bioscience, 55 (102928). [PMID:] [10.1016/j.fbio.2023.102928]
17. Xinmiao Wang, Qian Wang, Dong Cai, Xu Guo, Peiyong Tong, Fawen Yin, Xiaoyang Liu, Dayong Zhou. (2023) In Vitro Gastrointestinal Digestion and Microbial Hydrolysis of Hydroxytyrosol-SCFA and Tyrosol-SCFA Acyl Esters: Controlled-Release of SCFAs and Polyphenols. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (24): (9361–9369). [PMID:37294303] [10.1021/acs.jafc.3c00747]
18. Xinmiao Wang, Qian Wang, Jinghan Yu, Xu Guo, Peiyong Tong, Fawen Yin, Xiaoyang Liu, Dayong Zhou. (2023) The potential of hydroxytyrosol fatty acid esters to enhance oral bioavailabilities of hydroxytyrosol and fatty acids: Continuous and slow-release ability in small intestine and blood. FOOD CHEMISTRY, 422 (136246). [PMID:37126954] [10.1016/j.foodchem.2023.136246]
19. Yajuan Bai, Yue Zhou, Xiang Li, Ruifen Zhang, Fei Huang, Bei Fan, Litao Tong, Fengzhong Wang, Mingwei Zhang. (2023) Longan pulp polysaccharides regulate gut microbiota and metabolites to protect intestinal epithelial barrier. FOOD CHEMISTRY, 422 (136225). [PMID:37156018] [10.1016/j.foodchem.2023.136225]
20. Sathuvan Malairaj, Suresh Veeraperumal, Wanzi Yao, Mugesh Subramanian, Karsoon Tan, Saiyi Zhong, Kit-Leong Cheong. (2023) Porphyran from Porphyra haitanensis Enhances Intestinal Barrier Function and Regulates Gut Microbiota Composition. Marine Drugs, 21 (5): (265). [PMID:37233459] [10.3390/md21050265]
21. Lan Yang, Jiali Zhou, Yushuang Luo, Xincong Kang, Xihu Lai, Zhe Zhou, Xiaohong Zhong, Dongbo Liu. (2023) The regulatory effects of Lonicera japonica flos on fecal microbiota from humans with type 2 diabetes in a SHIME model. Journal of Herbal Medicine, 39 (100654). [PMID:] [10.1016/j.hermed.2023.100654]
22. Linlin Gao, Lin Zhang, Huan Liu, Jielun Hu. (2023) In vitro gastrointestinal digestion of whole grain noodles supplemented with soluble dietary fiber and their effects on children fecal microbiota. Food Bioscience, 53 (102600). [PMID:] [10.1016/j.fbio.2023.102600]
23. Xiang Li, Yan Du, Chengping Zhang, Li Wang. (2023) Black rice regulates lipid metabolism, liver injury, oxidative stress and adipose accumulation in high-fat/cholesterol diet mice based on gut microbiota and untargeted metabonomics. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 117 (109320). [PMID:36948432] [10.1016/j.jnutbio.2023.109320]
24. Xinmiao Wang, Qian Wang, Yuanyuan Hu, Fawen Yin, Xiaoyang Liu, Dayong Zhou. (2023) Hydrolysis and transport characteristics of tyrosol-SCFA esters in rat intestine and blood: Two-step release of tyrosol and SCFAs to enhance the beneficial effects. FOOD CHEMISTRY, 414 (135710). [PMID:36821923] [10.1016/j.foodchem.2023.135710]
25. Zhang Fangfang, Xiao Ying, Pan Liang, Yu Ling, Liu Yanfang, Li Deshun, Liu Xiaojie. (2023) Effects of polysaccharides from Lyophyllum decastes (Fr.) Singer on gut microbiota via in vitro-simulated digestion and fermentation. Frontiers in Microbiology, 14 [PMID:36860492] [10.3389/fmicb.2023.1083917]
26. Fangfang Min, Jielun Hu, Tao Huang, Yousheng Huang, Shaoping Nie, Tao Xiong, Mingyong Xie. (2023) Effects of Lactobacillus casei NCU011054 on immune response and gut microbiota of cyclophosphamide induced immunosuppression mice. FOOD AND CHEMICAL TOXICOLOGY, 174 (113662). [PMID:36775138] [10.1016/j.fct.2023.113662]
27. Yao Yuan, Feng Suya, Li Xuejiao, Liu Taohua, Ye Shengying, Ma Long, Man Shuli. (2023) Litchi procyanidins inhibit colon cancer proliferation and metastasis by triggering gut-lung axis immunotherapy. Cell Death & Disease, 14 (2): (1-11). [PMID:36774343] [10.1038/s41419-022-05482-5]
28. Rashidin Abdugheni, Dan-Hua Li, Yu-Jing Wang, Meng-Xuan Du, Nan Zhou, Chang Liu, Shuang-Jiang Liu. (2023) Acidaminococcus homini s sp. nov., Amedibacillus hominis sp. nov., Lientehia hominis gen. nov. sp. nov., Merdimmobilis hominis gen. nov. sp. nov., and Paraeggerthella hominis sp. nov., isolated from human faeces. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 73 (2): (5648). [PMID:36735588] [10.1099/ijsem.0.005648]
29. Xiaoyu Li, Siying An, Zhen Luo, Peng Zhou, Lu Wang, Ru Feng. (2023) Polysaccharides from the hard shells of Juglans regia L. modulate intestinal function and gut microbiota in vivo. FOOD CHEMISTRY, 412 (135592). [PMID:36736188] [10.1016/j.foodchem.2023.135592]
30. Yingyu Zhang, Yuan Sun, Yupei Liu, Jiameng Liu, Jing Sun, Yajuan Bai, Bei Fan, Cong Lu, Fengzhong Wang. (2023) Polygonum sibiricum polysaccharides alleviate chronic unpredictable mild stress-induced depressive-like behaviors by regulating the gut microbiota composition and SCFAs levels. Journal of Functional Foods, 101 (105411). [PMID:] [10.1016/j.jff.2023.105411]
31. Sibo Zhao, Shanshan Hu, Kang Sun, Liyong Luo, Liang Zeng. (2023) Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors. Food & Function, 14 (5): (2313-2325). [PMID:36779860] [10.1039/D2FO02780A]
32. Jianheng Guo, Yue Xu, Sunyan Liang, Zhengkun Zhou, Chunmei Zhang, Kui Li, Xue Peng, Sheng Qin, Ke Xing. (2023) Antifungal activity of volatile compounds from Bacillus tequilensis XK29 against Botrytis cinerea causing gray mold on cherry tomatoes. POSTHARVEST BIOLOGY AND TECHNOLOGY, 198 (112239). [PMID:] [10.1016/j.postharvbio.2022.112239]
33. Chen Xing-Ling, Cai Ke, Zhang Wen, Su Shu-Lan, Zhao Li-Hui, Qiu Li-Ping, Duan Jin-Ao. (2023) Bear bile powder ameliorates type 2 diabetes via modulation of metabolic profiles, gut microbiota, and metabolites. Frontiers in Pharmacology, 13 [PMID:36686652] [10.3389/fphar.2022.1090955]
34. Shanshan Hu, Zhiyuan Lin, Sibo Zhao, Bowen Zhang, Liyong Luo, Liang Zeng. (2023) Pu-erh tea alleviated colitis-mediated brain dysfunction by promoting butyric acid production. FOOD AND CHEMICAL TOXICOLOGY, 172 (113594). [PMID:36592713] [10.1016/j.fct.2022.113594]
35. Ni-Na Xie, Cheng-Ying Wu, Qiong Ge, Jing Zhou, Fang Long, Qian Mao, Song-Lin Li, Hong Shen. (2023) Structure-specific antitumor effects and potential gut microbiota-involved mechanisms of ginseng polysaccharides on B16F10 melanoma-bearing mice. Food & Function, 14 (2): (796-809). [PMID:36607268] [10.1039/D2FO03383F]
36. Chunlian Liu, Chengcheng Song, Yan Wang, Yangxin Xiao, Zhongshi Zhou, Guosheng Cao, Xiongjie Sun, Yanju Liu. (2023) Deep-fried Atractylodes lancea rhizome alleviates spleen deficiency diarrhea–induced short-chain fatty acid metabolic disorder in mice by remodeling the intestinal flora. JOURNAL OF ETHNOPHARMACOLOGY, 303 (115967). [PMID:36442762] [10.1016/j.jep.2022.115967]
37. Chuang Liu, Zhichang Qiu, Duanyin Gu, Fangzhou Wang, Rentang Zhang. (2023) A novel anti-inflammatory polysaccharide from blackened jujube: Structural features and protective effect on dextran sulfate sodium-induced colitic mice. FOOD CHEMISTRY, 405 (134869). [PMID:] [10.1016/j.foodchem.2022.134869]
38. Renjie Zhao, Zhichang Qiu, Xinyan Bai, Lu Xiang, Yiteng Qiao, Xiaoming Lu. (2022) Digestive properties and prebiotic activity of garlic saccharides with different-molecular-weight obtained by acidolysis. Current Research in Food Science, 5 (2033). [PMID:36337912] [10.1016/j.crfs.2022.10.022]
39. Xiang Li, Yan Du, Zhaoxin Tu, Chengping Zhang, Li Wang. (2022) Highland barley improves lipid metabolism, liver injury, antioxidant capacities and liver functions in high-fat/cholesterol diet mice based on gut microbiota and LC-MS metabonomics. Food Bioscience, 50 (102094). [PMID:] [10.1016/j.fbio.2022.102094]
40. Guopeng Li, Shugang Li, Huanhuan Liu, Lihua Zhang, Jingzhu Gao, Siteng Zhang, Yue Zou, Xiaodong Xia, Xiaomeng Ren. (2022) Isinglass Polysaccharides Regulate Intestinal-Barrier Function and Alleviate Obesity in High-Fat Diet Mice through the HO-1/Nrf2 Pathway and Intestinal Microbiome Environment. Nutrients, 14 (19): (3928). [PMID:36235584] [10.3390/nu14193928]
41. Yajuan Bai, Yue Zhou, Ruifen Zhang, Yanxia Chen, Fengzhong Wang, Mingwei Zhang. (2023) Gut microbial fermentation promotes the intestinal anti-inflammatory activity of Chinese yam polysaccharides. FOOD CHEMISTRY, 402 (134003). [PMID:36152553] [10.1016/j.foodchem.2022.134003]
42. Xiang Li, Yan Du, Chengping Zhang, Zhaoxin Tu, Li Wang. (2022) Modified highland barley regulates lipid metabolism, liver inflammation and gut microbiota in high-fat/cholesterol diet mice as revealed by LC-MS based metabonomics. Food & Function, 13 (17): (9119-9142). [PMID:35950689] [10.1039/D2FO00882C]
43. Liu Yue, Lin Yuzi, Li Ping, Yang Huiwen, Huang Qingsong, Pan Yufang. (2022) HS-GC with A Simple Pretreatment Protocol to Determine Short-chain Fatty Acids in Mouse Feces and the Effect of Polysaccharide from Acanthopanax trifoliatus (L.) Merr on Their Distribution in Diabetic Mice. CHROMATOGRAPHIA, 85 (9): (809-816). [PMID:] [10.1007/s10337-022-04187-3]
44. Yang Zheng, Yi Wang, Donghui Luo, Lianzhu Lin, Xingyu Lu, Jie Gao, Chuqiao Xiao, Mouming Zhao. (2022) Effect of Bergamot and Laoxianghuang Polysaccharides on Gut Microbiota Derived from Patients with Hyperlipidemia: An Integrative Analysis of Microbiome and Metabolome during In Vitro Fermentation. Foods, 11 (14): (2039). [PMID:35885282] [10.3390/foods11142039]
45. Wangting Zhou, Tingting Yang, Weiqi Xu, Yujie Huang, Linwu Ran, Yamei Yan, Jia Mi, Lu Lu, Yi Sun, Xiaoxiong Zeng, Youlong Cao. (2022) The polysaccharides from the fruits of Lycium barbarum L. confer anti-diabetic effect by regulating gut microbiota and intestinal barrier. CARBOHYDRATE POLYMERS, 291 (119626). [PMID:35698418] [10.1016/j.carbpol.2022.119626]
46. Anum Khan, Huma Ali, Ubaid Ur Rehman, Ali Osman Belduz, Amna Bibi, Mujib Abdulkadir Abdurahman, Aamer Ali Shah, Malik Badshah, Fariha Hasan, Ali Osman Kilic, Asad Ullah, Sarwat Jahan, Muhammad Maqsood Ur Rehman, Rashid Mansoor, Samiullah Khan. (2022) Prebiotic potential of enzymatically prepared resistant starch in reshaping gut microbiota and their respond to body physiology. PLoS One, 17 (5): (e0267318). [PMID:35576192] [10.1371/journal.pone.0267318]
47. Guijie Chen, Mingjia Wang, Ziqi Zeng, Minhao Xie, Weiqi Xu, Yujia Peng, Wangting Zhou, Yi Sun, Xiaoxiong Zeng, Zhonghua Liu. (2022) Fuzhuan brick tea polysaccharides serve as a promising candidate for remodeling the gut microbiota from colitis subjects in vitro: Fermentation characteristic and anti-inflammatory activity. FOOD CHEMISTRY, 391 (133203). [PMID:35597036] [10.1016/j.foodchem.2022.133203]
48. Shanshan Hu, Liyong Luo, Xintong Bian, Rui Hai Liu, Sibo Zhao, Yu Chen, Kang Sun, Jielin Jiang, Zhonghua Liu, Liang Zeng. (2022) Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (18): (5610–5623). [PMID:35475616] [10.1021/acs.jafc.2c01883]
49. Zheng Liu, Wen-ting Dong, Wen-feng Wei, Jin-hai Huo, Wei-ming Wang. (2022) Exploring the mechanism of Qinbaiqingfei-concentrate pills in the treatment of Mycoplasma pneumoniae pneumonia from the perspective of intestinal microbiota and mucosal immunity. JOURNAL OF ETHNOPHARMACOLOGY, 293 (115308). [PMID:35460847] [10.1016/j.jep.2022.115308]
50. Xiaoxu Cheng, Zifeng Pi, Zhong Zheng, Shu Liu, Fengrui Song, Zhiqiang Liu. (2022) Combined 16S rRNA gene sequencing and metabolomics to investigate the protective effects of Wu-tou decoction on rheumatoid arthritis in rats. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1199 (123249). [PMID:35447521] [10.1016/j.jchromb.2022.123249]
51. Yu-Heng Mao, Yixuan Xu, Fenglin Song, Zhao-Mei Wang, Yan-Heng Li, Mingzhu Zhao, Fang He, Zezhong Tian, Yan Yang. (2022) Protective effects of konjac glucomannan on gut microbiome with antibiotic perturbation in mice. CARBOHYDRATE POLYMERS, 290 (119476). [PMID:35550768] [10.1016/j.carbpol.2022.119476]
52. Qing Ge, Hang-qing Li, Zhe-yuan Zheng, Kai Yang, Peng Li, Zhu-qian Xiao, Guo-ming Xiao, Jian-wei Mao. (2022) In vitro fecal fermentation characteristics of bamboo insoluble dietary fiber and its impacts on human gut microbiota. FOOD RESEARCH INTERNATIONAL, 156 (111173). [PMID:35651096] [10.1016/j.foodres.2022.111173]
53. Wenyi Zhang, Bin Hu, Chang Liu, Hanyi Hua, Yahui Guo, Yuliang Cheng, Weirong Yao, He Qian. (2022) Comprehensive analysis of Sparassis crispa polysaccharide characteristics during the in vitro digestion and fermentation model. FOOD RESEARCH INTERNATIONAL, 154 (111005). [PMID:35337591] [10.1016/j.foodres.2022.111005]
54. Wenjing Liao, Wenjiao Li, Suyu Liu, Dong Tang, Yunxi Chen, Yijun Wang, Zhongwen Xie, Jinbao Huang. (2022) Potential prebiotic effects of nonabsorptive components of Keemun and Dianhong black tea: an in vitro study. Food Science and Human Wellness, 11 (648). [PMID:] [10.1016/j.fshw.2021.12.022]
55. Kun-Ping Li, Min Yuan, Yong-Lin Wu, Miguel Pineda, Chu-Mei Zhang, Yan-Fen Chen, Zhi-quan Chen, Xiang-Lu Rong, Jeremy E. Turnbull, Jiao Guo. (2022) A High-Fat High-Fructose Diet Dysregulates the Homeostatic Crosstalk Between Gut Microbiome, Metabolome, and Immunity in an Experimental Model of Obesity. MOLECULAR NUTRITION & FOOD RESEARCH, 66 (7): (2100950). [PMID:35072983] [10.1002/mnfr.202100950]
56. Zhiyong Xie, Yixuan Bai, Guijie Chen, Wei Dong, Yujia Peng, Weiqi Xu, Yi Sun, Xiaoxiong Zeng, Zhonghua Liu. (2022) Immunomodulatory activity of polysaccharides from the mycelium of Aspergillus cristatus, isolated from Fuzhuan brick tea, associated with the regulation of intestinal barrier function and gut microbiota. FOOD RESEARCH INTERNATIONAL, 152 (110901). [PMID:35181077] [10.1016/j.foodres.2021.110901]
57. Chu Wan, Kaizhang Wu, Xingyu Lu, Fang Fang, Yaqian Li, Yumin Zhao, Shubo Li, Jie Gao. (2021) Integrative Analysis of the Gut Microbiota and Metabolome for In Vitro Human Gut Fermentation Modeling. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 69 (50): (15414–15424). [PMID:34889098] [10.1021/acs.jafc.1c04259]
58. Yuan-Yuan Yao, Rui Xia, Ya-Lin Yang, Chen-Chen Gao, Feng-Li Zhang, Qiang Hao, Chao Ran, Zhen Zhang, Zhi-Gang Zhou. (2022) Dietary quenching enzyme AiiO-AIO6 promotes fish growth through intestinal microbiota: Zebrafish as a model. Aquaculture Reports, 22 (100947). [PMID:] [10.1016/j.aqrep.2021.100947]
59. Zhibo Fu, Qiangqiang Jia, Hongyang Zhang, Lu Kang, Xuezhi Sun, Min Zhang, Yuerong Wang, Ping Hu. (2022) Simultaneous quantification of eleven short-chain fatty acids by derivatization and solid phase microextraction - Gas chromatography tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, 1661 (462680). [PMID:34879311] [10.1016/j.chroma.2021.462680]
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Isobutyric acid - for synthesis, high purity , CAS No.79-31-2