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Isocarbostyril - 98%, high purity , CAS No.491-30-5

≥98%

CAS#: 491-30-5
Formula: C₉H₇NO
Molecular Weight: 145.16
Beilstein Registry Number: 2954
EC Number: 207-732-1
MDL number: MFCD00006899
PubChem CID: 10284

Item Number

I119399

Grouped product items
SKU	Size	Availability	Price
I119399-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$37.90
I119399-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$121.90
I119399-10g	10g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$218.90
I119399-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$492.90
I119399-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,772.90

View related series

Halogen free heterocyclic block quinolines

Basic Description

Synonyms	SY004064 \| 2(1H)-ISOQUINOLINONE \| AI3-62131 \| Isoquinolin-1-one \| isoquinolinol \| HMS1760O13 \| 4YS \| BCP23848 \| MFCD00006899 \| 1(2H)-ISOQUINILONE \| Isocarbostyril (VAN) \| AKOS007930083 \| NSC 27273 \| 1-oxo-1,2-dihydroisoquinoline \| SCHEMBL57212 \| AKOS00105
Specifications & Purity	≥98%
Shipped In	Normal

Associated Targets(Human)

PARP1 Tclin Poly [ADP-ribose] polymerase 1 (1 Activities)

Discover Target: PARP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PARP1 Tclin Poly [ADP-ribose] polymerase-1 (6206 Activities)

Discover Target: PARP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

F7 Tchem Coagulation factor VII/tissue factor (740 Activities)

Discover Target: F7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IUPAC Name

2H-isoquinolin-1-one

INCHI

InChI=1S/C9H7NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-6H,(H,10,11)

InChi Key

VDBNYAPERZTOOF-UHFFFAOYSA-N

Canonical SMILES

C1=CC=C2C(=C1)C=CNC2=O

Isomeric SMILES

C1=CC=C2C(=C1)C=CNC2=O

WGK Germany

PubChem CID

10284

Molecular Weight

145.16

Beilstein

2954

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3

References

1. R Erra-Balsells,A A Kolender,M C Matulewicz,H Nonami,A S Cerezo. (2000-11-22) Matrix-assisted ultraviolet laser-desorption ionization time-of-flight mass spectrometry of sulfated mannans from the red seaweed Nothogenia fastigiata.. Carbohydrate research, 329 ((1)): (157-167). [PMID:11086695]
2. Dana V Ferraris. (2010-04-07) Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic.. Journal of medicinal chemistry, 53 ((12)): (4561-4584). [PMID:20364863]
3. Yang-Min Ma,Ke Qiao,Yang Kong,Meng-Yun Li,Lin-Xin Guo,Zhi Miao,Chao Fan. (2016-12-03) A new isoquinolone alkaloid from an endophytic fungus R22 of Nerium indicum.. Natural product research, 31 ((8)): (951-958). [PMID:27910702]
4. Usman Ali,Swati Kanwar,Kamalendra Yadav,Santanu Basu,Koushik Mazumder. (2019-02-09) Effect of arabinoxylan and β-glucan stearic acid ester coatings on post-harvest quality of apple (Royal Delicious).. Carbohydrate polymers, 209 (338-349). [PMID:30732816]
5. Luca Palazzo,Petra Mikolčević,Andreja Mikoč,Ivan Ahel. (2019-04-18) ADP-ribosylation signalling and human disease.. Open biology, 9 ((4)): (190041-190041). [PMID:30991935]
6. David J Harvey. (2020-04-25) NEGATIVE ION MASS SPECTROMETRY FOR THE ANALYSIS OF N-LINKED GLYCANS.. Mass spectrometry reviews, 39 ((5-6)): (586-679). [PMID:32329121]
7. N K Richards,H K Mahanty,J Aislabie. (1994-07-01) Construction of a DNA probe to detect isoquinoline-degrading bacteria.. Canadian journal of microbiology, 40 ((7)): (561-566). [PMID:8076251]
8. M Berger,Y Wu,A K Ogawa,D L McMinn,P G Schultz,F E Romesberg. (2000-07-25) Universal bases for hybridization, replication and chain termination.. Nucleic acids research, 28 ((15)): (2911-2914). [PMID:10908353]
9. Yasuhiro Torisawa,Shinji Aki,Jun-ichi Minamikawa. (2006-10-27) Conversion of indanone oximes into isocarbostyrils.. Bioorganic & medicinal chemistry letters, 17 ((2)): (453-455). [PMID:17064893]
10. Yalin Zhang,Han Su,Juan Zhang,Juan Kong. (2019-07-18) The Effects of Ginsenosides and Anserine on the Up-Regulation of Renal Aquaporins 1-4 in Hyperuricemic Mice.. The American journal of Chinese medicine, 47 ((5)): (1133-1147). [PMID:31311296]
11. Tarun Belwal,Aarti Bisht,Hari Prasad Devkota,Hammad Ullah,Haroon Khan,Aseesh Pandey,Indra Dutt Bhatt,Javier Echeverría. (2020-03-07) Phytopharmacology and Clinical Updates of Berberis Species Against Diabetes and Other Metabolic Diseases.. Frontiers in pharmacology, 11 (41-41). [PMID:32132921]

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Isocarbostyril - 98%, high purity , CAS No.491-30-5

Basic Description

Associated Targets(Human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

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