Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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I102825-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $124.90 |
Inhibits COX-dependent PGD2 production
Synonyms | IGWDEVSBEKYORK-UHFFFAOYSA-N | Iso Imperatorin | CCG-267156 | MEGxp0_000090 | UNII-0ZMV066080 | 7,4-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]-1-benzopyran-7-one | 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3-methyl-2-butenyl)oxy)- | 4-(3-methylbut-2-enoxy)furo[ |
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Specifications & Purity | analytical standard, Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Inhibits COX-dependent PGD2 production (IC 50 values are 11 and 24 μM for COX-1 and COX-2 respectively). Inhibits LTC4 production (IC 50 = 6 μM). Shows antiproliferative effects. Shows vasodilatory and anti-inflammatory effects in vivo. Orally active. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard, Moligand™ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one |
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INCHI | InChI=1S/C16H14O4/c1-10(2)5-7-19-16-11-3-4-15(17)20-14(11)9-13-12(16)6-8-18-13/h3-6,8-9H,7H2,1-2H3 |
InChi Key | IGWDEVSBEKYORK-UHFFFAOYSA-N |
Canonical SMILES | CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C |
Isomeric SMILES | CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C |
PubChem CID | 68081 |
Molecular Weight | 270.28 |
Enter Lot Number to search for COA:
Sensitivity | Heat sensitive |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
1. Congyi Zhu, Cheng Peng, Diyang Qiu, Jiwu Zeng. (2022) Metabolic Profiling and Transcriptional Analysis of Carotenoid Accumulation in a Red-Fleshed Mutant of Pummelo (Citrus grandis). MOLECULES, 27 (14): (4595). [PMID:35889470] [10.3390/molecules27144595] |
1. Congyi Zhu, Cheng Peng, Diyang Qiu, Jiwu Zeng. (2022) Metabolic Profiling and Transcriptional Analysis of Carotenoid Accumulation in a Red-Fleshed Mutant of Pummelo (Citrus grandis). MOLECULES, 27 (14): (4595). [PMID:35889470] [10.3390/molecules27144595] |