| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| I424191-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $103.90 |
Inhibits COX-dependent PGD2 production
| Synonyms | Isoimperatorin | 482-45-1 | Iso-imperatorin | Iso Imperatorin | 4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one | 4-PRENYLOXYPSORALEN | UNII-0ZMV066080 | CHEBI:66071 | 4-[(3-methylbut-2-en-1-yl)oxy]-7h-furo[3,2-g]chromen-7-one | 0ZMV066080 | CHEMBL448060 | HSDB 8496 | 4-((3-meth |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Inhibits COX-dependent PGD2 production (IC 50 values are 11 and 24 μM for COX-1 and COX-2 respectively). Inhibits LTC4 production (IC 50 = 6 μM). Shows antiproliferative effects. Shows vasodilatory and anti-inflammatory effects in vivo. Orally active. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
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| IUPAC Name | 4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one |
|---|---|
| INCHI | InChI=1S/C16H14O4/c1-10(2)5-7-19-16-11-3-4-15(17)20-14(11)9-13-12(16)6-8-18-13/h3-6,8-9H,7H2,1-2H3 |
| InChi Key | IGWDEVSBEKYORK-UHFFFAOYSA-N |
| Canonical SMILES | CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C |
| Isomeric SMILES | CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C |
| PubChem CID | 68081 |
| Molecular Weight | 270.28 |
Enter Lot Number to search for COA:
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H317:May cause an allergic skin reaction |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| 1. Congyi Zhu, Cheng Peng, Diyang Qiu, Jiwu Zeng. (2022) Metabolic Profiling and Transcriptional Analysis of Carotenoid Accumulation in a Red-Fleshed Mutant of Pummelo (Citrus grandis). MOLECULES, 27 (14): (4595). [PMID:35889470] [10.3390/molecules27144595] |
| 1. Congyi Zhu, Cheng Peng, Diyang Qiu, Jiwu Zeng. (2022) Metabolic Profiling and Transcriptional Analysis of Carotenoid Accumulation in a Red-Fleshed Mutant of Pummelo (Citrus grandis). MOLECULES, 27 (14): (4595). [PMID:35889470] [10.3390/molecules27144595] |
