Isonicotinic acid hydrazide - 98%, high purity , CAS No.54-85-3

1 Citations
  • ≥98%
Item Number
I104690
Grouped product items
SKUSizeAvailabilityPrice Qty
I104690-25g
25g
In stock
$9.90
I104690-50g
50g
In stock
$16.90
I104690-100g
100g
In stock
$23.90
I104690-250g
250g
In stock
$53.90
I104690-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$85.90

Basic Description

Synonymsisoniazid | 54-85-3 | Isonicotinic acid hydrazide | Isonicotinohydrazide | pyridine-4-carbohydrazide | Isoniazide | Nydrazid | Rimifon | Cotinazin | Hydrazid | Iscotin | Mybasan | Isonicotinylhydrazine | Atcotibine | Hidrasonil | Isobicina | Isonicotan | Neumandin | Armazid | Armazide | Dinacri
Specifications & Purity≥98%
Biochemical and Physiological MechanismsAntibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibi
Storage TempProtected from light,Argon charged
Shipped InNormal

Product Properties

ALogP-0.7

Associated Targets(non-human)

gyrB DNA gyrase subunit B (290 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fabI Enoyl-[acyl-carrier-protein] reductase (206 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Htr7 Serotonin 7 (5-HT7) receptor (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ntsr1 Neurotensin receptor 1 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bdkrb1 Bradykinin B1 receptor (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase (152 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pneumoniae (31063 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus vulgaris (5823 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Shigella sp. (79 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Micrococcus luteus (7463 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus hominis (482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bordetella bronchiseptica (483 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Citrobacter koseri (193 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella aerogenes (4963 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella sp. (156 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Morganella morganii (1291 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus mirabilis (3894 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhi (4293 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pyogenes (16140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecium (13803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus niger (16508 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Listeria monocytogenes (2626 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium (258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium avium (4587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycolicibacterium fortuitum (1335 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium kansasii (6484 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycolicibacterium phlei (631 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium gordonae (69 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488179793
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179793
IUPAC Name pyridine-4-carbohydrazide
INCHI InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
InChi Key QRXWMOHMRWLFEY-UHFFFAOYSA-N
Canonical SMILES C1=CN=CC=C1C(=O)NN
Isomeric SMILES C1=CN=CC=C1C(=O)NN
WGK Germany 3
RTECS NS1751850
PubChem CID 3767
Molecular Weight 137.14
Beilstein 119374

Certificates

Certificate of Analysis(COA)

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40 results found

Lot NumberCertificate TypeDateItem
I2403450Certificate of AnalysisSep 04, 2024 I104690
I2403449Certificate of AnalysisSep 04, 2024 I104690
I2403448Certificate of AnalysisSep 04, 2024 I104690
I2403451Certificate of AnalysisSep 04, 2024 I104690
C2420245Certificate of AnalysisMar 25, 2024 I104690
C2420247Certificate of AnalysisMar 25, 2024 I104690
C2420251Certificate of AnalysisMar 22, 2024 I104690
C2419295Certificate of AnalysisMar 12, 2024 I104690
C2419293Certificate of AnalysisMar 12, 2024 I104690
C2419294Certificate of AnalysisMar 12, 2024 I104690
K2310108Certificate of AnalysisNov 17, 2023 I104690
K2310107Certificate of AnalysisNov 17, 2023 I104690
K2310105Certificate of AnalysisNov 17, 2023 I104690
K2310106Certificate of AnalysisNov 17, 2023 I104690
I2328180Certificate of AnalysisOct 09, 2023 I104690
I2328181Certificate of AnalysisOct 09, 2023 I104690
H2310017Certificate of AnalysisAug 17, 2023 I104690
E2322382Certificate of AnalysisMay 26, 2023 I104690
E2322265Certificate of AnalysisMay 25, 2023 I104690
E2322271Certificate of AnalysisMay 25, 2023 I104690
E2322274Certificate of AnalysisMay 25, 2023 I104690
E2322275Certificate of AnalysisMay 25, 2023 I104690
E2322383Certificate of AnalysisMay 25, 2023 I104690
G2328025Certificate of AnalysisMay 25, 2023 I104690
E2322353Certificate of AnalysisMay 24, 2023 I104690
D2326029Certificate of AnalysisMay 12, 2023 I104690
D2324125Certificate of AnalysisMay 09, 2023 I104690
C2323009Certificate of AnalysisMar 29, 2023 I104690
C2320414Certificate of AnalysisMar 25, 2023 I104690
K2228246Certificate of AnalysisDec 09, 2022 I104690
C2328217Certificate of AnalysisDec 09, 2022 I104690
B2316331Certificate of AnalysisDec 09, 2022 I104690
J2231124Certificate of AnalysisNov 03, 2022 I104690
J2220056Certificate of AnalysisOct 22, 2022 I104690
J2210503Certificate of AnalysisOct 13, 2022 I104690
J2210504Certificate of AnalysisOct 13, 2022 I104690
J2210505Certificate of AnalysisOct 13, 2022 I104690
D2319343Certificate of AnalysisOct 13, 2022 I104690
H2217024Certificate of AnalysisAug 23, 2022 I104690
G1818092Certificate of AnalysisMay 10, 2022 I104690

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Chemical and Physical Properties

SensitivityAir sensitive
Melt Point(°C)171.4°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H302:Harmful if swallowed

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 3
RTECS NS1751850
Merck Index 5186

Related Documents

Citations of This Product

1. Ting Li, Chaoyue Yang, Houkang Cao, Siyi Mo, Bo Li, Zhipeng Huang, Ruobing Zhang, Jianzhao Wu, Kefeng Zhang, Ya Gao.  (2023)  The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing.  MOLECULES,  28  (14): (5496).  [PMID:37513369]

References

1. Ting Li, Chaoyue Yang, Houkang Cao, Siyi Mo, Bo Li, Zhipeng Huang, Ruobing Zhang, Jianzhao Wu, Kefeng Zhang, Ya Gao.  (2023)  The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing.  MOLECULES,  28  (14): (5496).  [PMID:37513369]

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