Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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I115856-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $218.90 | |
I115856-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $393.90 |
Selective Cyclooxygenase-2 (COX-2) inhibitor.
Synonyms | Isoorientin, primary pharmaceutical reference standard | MLS002473101 | HMS2225D20 | 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-.beta.-D-glucopyranosyl-5,7-dihydroxy- | Q3155592 | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-((2S,3R,4R,5S,6R)-3,4,5-trihy |
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Specifications & Purity | analytical standard, ≥98% |
Biochemical and Physiological Mechanisms | C-glycosyl flavone that can be isolated from the passion flower, and several other species of plants. Has anti-inflammatory, antimicrobial and antioxidant properties. Selective Cyclooxygenase-2 (COX-2) inhibitor. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one |
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INCHI | InChI=1S/C21H20O11/c22-6-14-17(27)19(29)20(30)21(32-14)16-11(26)5-13-15(18(16)28)10(25)4-12(31-13)7-1-2-8(23)9(24)3-7/h1-5,14,17,19-24,26-30H,6H2/t14-,17-,19+,20-,21+/m1/s1 |
InChi Key | ODBRNZZJSYPIDI-VJXVFPJBSA-N |
Canonical SMILES | C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)C4C(C(C(C(O4)CO)O)O)O)O)O)O |
Isomeric SMILES | C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O |
WGK Germany | 3 |
PubChem CID | 114776 |
Molecular Weight | 448.38 |
Melt Point(°C) | 245-246°C |
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WGK Germany | 3 |
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1. Zuo Jingru, Liu Lianjie, Hou Simeng, Liu Xiaoqiang, Teng Jiang, Li Pei, Liu Xiaotong. (2023) Antimicrobial and antibiofilm activity of isoorientin against carbapenem non-sensitive Escherichia coli from raw milk of goats. JOURNAL OF ANIMAL SCIENCE, 101 [PMID:36762933] [10.1093/jas/skad047] |
2. Ying Li, Bo Chen, Hai-Yan Cao, Jing-En Li, Ling-Li Chen, Qing-Feng Zhang. (2021) Pancreatic lipase inhibitory activity of Bambusa multiplex cv. Fernleaf leaf extract in vitro and in vivo. Food & Function, 12 (16): (7440-7447). [PMID:34195734] [10.1039/D1FO01168E] |
3. Hui Guo, Yunfei Chen, Na Song, Xinyi Yang, Shen Yao, Junqing Qian. (2020) Screening of lipase inhibitors from bamboo leaves based on the magnetic ligand fishing combined with HPLC/MS. MICROCHEMICAL JOURNAL, 153 (104497). [PMID:] [10.1016/j.microc.2019.104497] |
4. Lingyi Liu, Meirong Pang, Ying Zhang. (2015) Lipase-catalyzed regioselective synthesis of flavone C-glucosides esters and high-efficiency oil-soluble antioxidant of bamboo leaves (eAOB-o). EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 117 (10): (1636-1646). [PMID:] [10.1002/ejlt.201400541] |
1. Zuo Jingru, Liu Lianjie, Hou Simeng, Liu Xiaoqiang, Teng Jiang, Li Pei, Liu Xiaotong. (2023) Antimicrobial and antibiofilm activity of isoorientin against carbapenem non-sensitive Escherichia coli from raw milk of goats. JOURNAL OF ANIMAL SCIENCE, 101 [PMID:36762933] [10.1093/jas/skad047] |
2. Ying Li, Bo Chen, Hai-Yan Cao, Jing-En Li, Ling-Li Chen, Qing-Feng Zhang. (2021) Pancreatic lipase inhibitory activity of Bambusa multiplex cv. Fernleaf leaf extract in vitro and in vivo. Food & Function, 12 (16): (7440-7447). [PMID:34195734] [10.1039/D1FO01168E] |
3. Hui Guo, Yunfei Chen, Na Song, Xinyi Yang, Shen Yao, Junqing Qian. (2020) Screening of lipase inhibitors from bamboo leaves based on the magnetic ligand fishing combined with HPLC/MS. MICROCHEMICAL JOURNAL, 153 (104497). [PMID:] [10.1016/j.microc.2019.104497] |
4. Lingyi Liu, Meirong Pang, Ying Zhang. (2015) Lipase-catalyzed regioselective synthesis of flavone C-glucosides esters and high-efficiency oil-soluble antioxidant of bamboo leaves (eAOB-o). EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 117 (10): (1636-1646). [PMID:] [10.1002/ejlt.201400541] |