Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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I109591-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $103.90 | |
I109591-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $168.90 |
Synonyms | NCGC00163572-02 | 3'-Methoxyquercetin | 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one | SR-05000002256-2 | I1068 | 3,4',5,7-Tetrahydroxy-3'-methoxyflavone | 3,4',5,7-tetrahydroxy-3'-methoxy-flavone | EX-A6804 | Isorhamnetol | UNII-0 |
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Specifications & Purity | analytical standard, ≥98%(HPLC) |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one |
---|---|
INCHI | InChI=1S/C16H12O7/c1-22-11-4-7(2-3-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3 |
InChi Key | IZQSVPBOUDKVDZ-UHFFFAOYSA-N |
Canonical SMILES | COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O |
Isomeric SMILES | COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O |
WGK Germany | 3 |
RTECS | LK9275450 |
PubChem CID | 5281654 |
Molecular Weight | 316.26 |
Beilstein | 44723 |
Reaxy-Rn | 44723 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B2311762 | Certificate of Analysis | Nov 07, 2024 | I109591 |
C2228047 | Certificate of Analysis | Jan 08, 2024 | I109591 |
C2228058 | Certificate of Analysis | Jan 08, 2024 | I109591 |
I2311550 | Certificate of Analysis | Aug 21, 2023 | I109591 |
I2126284 | Certificate of Analysis | Jul 07, 2023 | I109591 |
B2311608 | Certificate of Analysis | Nov 28, 2022 | I109591 |
Melt Point(°C) | 307°C |
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Pictogram(s) | GHS08 |
---|---|
Signal | Warning |
Hazard Statements | H351:Suspected of causing cancer |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
WGK Germany | 3 |
RTECS | LK9275450 |
Reaxy-Rn | 44723 |
Starting at $241.90
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1. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang. (2023) Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF. Analytical Methods, 15 (24): (2964-2970). [PMID:37309583] |
2. Liao Zhenkun, Liu Xiaojuan, Zheng Juan, Zhao Chenning, Wang Dengliang, Xu Yang, Sun Chongde. (2023) A multifunctional true caffeoyl coenzyme A O-methyltransferase enzyme participates in the biosynthesis of polymethoxylated flavones in citrus. PLANT PHYSIOLOGY, [PMID:37086474] |
3. Fangping Liang, Wurong Li, Mingao Li, Xican Li, Jianfeng He, Quanzhou Wu. (2023) Kaempferol molecularly imprinted polymers: preparation, characterization and application to the separation of kaempferol from ginkgo leaves. POLYMER INTERNATIONAL, 72 (6): (586-596). [PMID:] |
4. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] |
5. Jiao Wu, Bingjun Han, Xiaoyu Chen, Jinglin Gao, Shan Zhao, Liping Sun, Shijie Wang. (2023) Quantification of bioactive components and evaluation of microbial community and antibacterial activity from Heterotrigona itama and Tetrigona binghami honeys. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (5): (2247-2257). [PMID:] |
6. Shi Xia, Fang Jiaxing, Du Huicong, Zhang Sufang, Liu Fu, Zhang Zhen, Kong Xiangbo. (2022) Performance of two Ips bark beetles and their associated pathogenic fungi on hosts reflects a species-specific association in the beetle-fungus complex. Frontiers in Plant Science, 13 [PMID:36483952] |
7. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] |
8. Ping-Rong Zhou, Zhang-Feng Tang, Ke-Su Wei, Ya Wan, Yu-Meng Gao, Yan-Mei Liang, Xiu-Fang Yan, Jun Bin, Chao Kang. (2021) Enhanced Selectivity of Ultraviolet-Visible Absorption Spectroscopy with Trilinear Decomposition on Spectral pH Measurements for the Interference-Free Determination of Rutin and Isorhamnetin in Chinese Herbal Medicine. ANALYTICAL LETTERS, [PMID:] |
9. Wu Yuqin, Fan Lin, Wang Yun, Ding Jing, Wang Rongfu. (2021) Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt/SIRT1/Nrf2/HO-1 Signaling Pathway. INFLAMMATION, 44 (5): (1993-2005). [PMID:33999329] |
10. Yuanyuan Gao, Ahui Xue, Xiang Li, Xueyong Huang, Fangjian Ning, Xiaoping Zhang, Tao Liu, Huanwen Chen, Liping Luo. (2020) Analysis of chemical composition of nectars and honeys from Citrus by extractive electrospray ionization high resolution mass spectrometry. LWT-FOOD SCIENCE AND TECHNOLOGY, 131 (109748). [PMID:] |
11. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] |
12. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] |
13. Liu Xiaojuan, Zhao Chenning, Gong Qin, Wang Yue, Cao Jinping, Li Xian, Grierson Donald, Sun Chongde. (2020) Characterization of a caffeoyl-CoA O-methyltransferase-like enzyme involved in biosynthesis of polymethoxylated flavones in Citrus reticulata. JOURNAL OF EXPERIMENTAL BOTANY, 71 (10): (3066-3079). [PMID:32182355] |
14. Xiaojuan Liu, Yue Wang, Yezhi Chen, Shuting Xu, Qin Gong, Chenning Zhao, Jinping Cao, Chongde Sun. (2020) Characterization of a Flavonoid 3’/5’/7-O-Methyltransferase from Citrus reticulata and Evaluation of the In Vitro Cytotoxicity of Its Methylated Products. MOLECULES, 25 (4): (858). [PMID:32075249] |
15. Lingling Wang, Xiuhua Zhao, Fengjian Yang, Weiwei Wu, Yanjie Liu, Li Wang, Lu Wang, Zijian Wang. (2019) Enhanced bioaccessibility in vitro and bioavailability of Ginkgo biloba extract nanoparticles prepared by liquid anti-solvent precipitation. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 54 (6): (2266-2276). [PMID:] |
16. Longhua Xu, Mingfei Pan, Guozhen Fang, Shuo Wang. (2019) Carbon dots embedded metal-organic framework@molecularly imprinted nanoparticles for highly sensitive and selective detection of quercetin. SENSORS AND ACTUATORS B-CHEMICAL, 286 (321). [PMID:] |
17. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943] |
18. Jian Liu, Lifang Ji, Lei Chen, Kemei Pei, Peng Zhao, Yang Zhou, Feng Zhao. (2018) Identification of yellow dyes in two wall coverings from the Palace Museum: Evidence for reconstitution of artifacts. DYES AND PIGMENTS, 153 (137). [PMID:] |
19. Xijuan Tu, Shuangqin Ma, Zhaosheng Gao, Jing Wang, Shaokang Huang, Wenbin Chen. (2017) One-Step Extraction and Hydrolysis of Flavonoid Glycosides in Rape Bee Pollen Based on Soxhlet-Assisted Matrix Solid Phase Dispersion. PHYTOCHEMICAL ANALYSIS, 28 (6): (505-511). [PMID:28597993] |
20. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang. (2017) Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr). Journal of Functional Foods, 32 (296). [PMID:] |
21. Longhua Xu, Guozhen Fang, Jifeng Liu, Mingfei Pan, Ranran Wang, Shuo Wang. (2016) One-pot synthesis of nanoscale carbon dots-embedded metal–organic frameworks at room temperature for enhanced chemical sensing. Journal of Materials Chemistry A, 4 (41): (15880-15887). [PMID:] |
22. Lingling Wang, Xiuhua Zhao, Yuangang Zu, Weiwei Wu, Yuanyuan Li, Chang Zu, Yin Zhang. (2016) Enhanced dissolution rate and oral bioavailability of ginkgo biloba extract by preparing nanoparticles via emulsion solvent evaporation combined with freeze drying (ESE-FR). RSC Advances, 6 (81): (77346-77357). [PMID:] |
23. Yuan Gang Zu, Lingling Wang, Xiuhua Zhao, Yuanyuan Li, Weiwei Wu, Chang Zu, Yannian Huang, Mingfang Wu, Ziqi Feng. (2016) Purification of Ginkgo biloba Extract by Antisolvent Recrystallization. CHEMICAL ENGINEERING & TECHNOLOGY, 39 (7): (1301-1308). [PMID:] |
24. Houmei Liu, Mingliang Zhang, Yong Guo, Hongdeng Qiu. (2016) Solid-phase extraction of flavonoids in honey samples using carbamate-embedded triacontyl-modified silica sorbent. FOOD CHEMISTRY, 204 (56). [PMID:26988475] |
25. Yong Liu, Huifang Zhang, Shoulian Wei. (2015) Ultrasonic-assisted extraction of pigments from Hylocereus undatus flowers: optimization, antioxidant activity, and HPLC analysis. RSC Advances, 5 (58): (46598-46607). [PMID:] |
26. Shi Shen,Jingbo Wang,Qin Zhuo,Xi Chen,Tingting Liu,Shuang-Qing Zhang. (2018-05-09) Quantitative and Discriminative Evaluation of Contents of Phenolic and Flavonoid and Antioxidant Competence for Chinese Honeys from Different Botanical Origins.. Molecules (Basel, Switzerland), 23 ((5)): [PMID:29738446] |
1. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang. (2023) Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF. Analytical Methods, 15 (24): (2964-2970). [PMID:37309583] |
2. Liao Zhenkun, Liu Xiaojuan, Zheng Juan, Zhao Chenning, Wang Dengliang, Xu Yang, Sun Chongde. (2023) A multifunctional true caffeoyl coenzyme A O-methyltransferase enzyme participates in the biosynthesis of polymethoxylated flavones in citrus. PLANT PHYSIOLOGY, [PMID:37086474] |
3. Fangping Liang, Wurong Li, Mingao Li, Xican Li, Jianfeng He, Quanzhou Wu. (2023) Kaempferol molecularly imprinted polymers: preparation, characterization and application to the separation of kaempferol from ginkgo leaves. POLYMER INTERNATIONAL, 72 (6): (586-596). [PMID:] |
4. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] |
5. Jiao Wu, Bingjun Han, Xiaoyu Chen, Jinglin Gao, Shan Zhao, Liping Sun, Shijie Wang. (2023) Quantification of bioactive components and evaluation of microbial community and antibacterial activity from Heterotrigona itama and Tetrigona binghami honeys. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (5): (2247-2257). [PMID:] |
6. Shi Xia, Fang Jiaxing, Du Huicong, Zhang Sufang, Liu Fu, Zhang Zhen, Kong Xiangbo. (2022) Performance of two Ips bark beetles and their associated pathogenic fungi on hosts reflects a species-specific association in the beetle-fungus complex. Frontiers in Plant Science, 13 [PMID:36483952] |
7. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] |
8. Ping-Rong Zhou, Zhang-Feng Tang, Ke-Su Wei, Ya Wan, Yu-Meng Gao, Yan-Mei Liang, Xiu-Fang Yan, Jun Bin, Chao Kang. (2021) Enhanced Selectivity of Ultraviolet-Visible Absorption Spectroscopy with Trilinear Decomposition on Spectral pH Measurements for the Interference-Free Determination of Rutin and Isorhamnetin in Chinese Herbal Medicine. ANALYTICAL LETTERS, [PMID:] |
9. Wu Yuqin, Fan Lin, Wang Yun, Ding Jing, Wang Rongfu. (2021) Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt/SIRT1/Nrf2/HO-1 Signaling Pathway. INFLAMMATION, 44 (5): (1993-2005). [PMID:33999329] |
10. Yuanyuan Gao, Ahui Xue, Xiang Li, Xueyong Huang, Fangjian Ning, Xiaoping Zhang, Tao Liu, Huanwen Chen, Liping Luo. (2020) Analysis of chemical composition of nectars and honeys from Citrus by extractive electrospray ionization high resolution mass spectrometry. LWT-FOOD SCIENCE AND TECHNOLOGY, 131 (109748). [PMID:] |
11. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] |
12. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] |
13. Liu Xiaojuan, Zhao Chenning, Gong Qin, Wang Yue, Cao Jinping, Li Xian, Grierson Donald, Sun Chongde. (2020) Characterization of a caffeoyl-CoA O-methyltransferase-like enzyme involved in biosynthesis of polymethoxylated flavones in Citrus reticulata. JOURNAL OF EXPERIMENTAL BOTANY, 71 (10): (3066-3079). [PMID:32182355] |
14. Xiaojuan Liu, Yue Wang, Yezhi Chen, Shuting Xu, Qin Gong, Chenning Zhao, Jinping Cao, Chongde Sun. (2020) Characterization of a Flavonoid 3’/5’/7-O-Methyltransferase from Citrus reticulata and Evaluation of the In Vitro Cytotoxicity of Its Methylated Products. MOLECULES, 25 (4): (858). [PMID:32075249] |
15. Lingling Wang, Xiuhua Zhao, Fengjian Yang, Weiwei Wu, Yanjie Liu, Li Wang, Lu Wang, Zijian Wang. (2019) Enhanced bioaccessibility in vitro and bioavailability of Ginkgo biloba extract nanoparticles prepared by liquid anti-solvent precipitation. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 54 (6): (2266-2276). [PMID:] |
16. Longhua Xu, Mingfei Pan, Guozhen Fang, Shuo Wang. (2019) Carbon dots embedded metal-organic framework@molecularly imprinted nanoparticles for highly sensitive and selective detection of quercetin. SENSORS AND ACTUATORS B-CHEMICAL, 286 (321). [PMID:] |
17. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943] |
18. Jian Liu, Lifang Ji, Lei Chen, Kemei Pei, Peng Zhao, Yang Zhou, Feng Zhao. (2018) Identification of yellow dyes in two wall coverings from the Palace Museum: Evidence for reconstitution of artifacts. DYES AND PIGMENTS, 153 (137). [PMID:] |
19. Xijuan Tu, Shuangqin Ma, Zhaosheng Gao, Jing Wang, Shaokang Huang, Wenbin Chen. (2017) One-Step Extraction and Hydrolysis of Flavonoid Glycosides in Rape Bee Pollen Based on Soxhlet-Assisted Matrix Solid Phase Dispersion. PHYTOCHEMICAL ANALYSIS, 28 (6): (505-511). [PMID:28597993] |
20. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang. (2017) Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr). Journal of Functional Foods, 32 (296). [PMID:] |
21. Longhua Xu, Guozhen Fang, Jifeng Liu, Mingfei Pan, Ranran Wang, Shuo Wang. (2016) One-pot synthesis of nanoscale carbon dots-embedded metal–organic frameworks at room temperature for enhanced chemical sensing. Journal of Materials Chemistry A, 4 (41): (15880-15887). [PMID:] |
22. Lingling Wang, Xiuhua Zhao, Yuangang Zu, Weiwei Wu, Yuanyuan Li, Chang Zu, Yin Zhang. (2016) Enhanced dissolution rate and oral bioavailability of ginkgo biloba extract by preparing nanoparticles via emulsion solvent evaporation combined with freeze drying (ESE-FR). RSC Advances, 6 (81): (77346-77357). [PMID:] |
23. Yuan Gang Zu, Lingling Wang, Xiuhua Zhao, Yuanyuan Li, Weiwei Wu, Chang Zu, Yannian Huang, Mingfang Wu, Ziqi Feng. (2016) Purification of Ginkgo biloba Extract by Antisolvent Recrystallization. CHEMICAL ENGINEERING & TECHNOLOGY, 39 (7): (1301-1308). [PMID:] |
24. Houmei Liu, Mingliang Zhang, Yong Guo, Hongdeng Qiu. (2016) Solid-phase extraction of flavonoids in honey samples using carbamate-embedded triacontyl-modified silica sorbent. FOOD CHEMISTRY, 204 (56). [PMID:26988475] |
25. Yong Liu, Huifang Zhang, Shoulian Wei. (2015) Ultrasonic-assisted extraction of pigments from Hylocereus undatus flowers: optimization, antioxidant activity, and HPLC analysis. RSC Advances, 5 (58): (46598-46607). [PMID:] |
26. Shi Shen,Jingbo Wang,Qin Zhuo,Xi Chen,Tingting Liu,Shuang-Qing Zhang. (2018-05-09) Quantitative and Discriminative Evaluation of Contents of Phenolic and Flavonoid and Antioxidant Competence for Chinese Honeys from Different Botanical Origins.. Molecules (Basel, Switzerland), 23 ((5)): [PMID:29738446] |