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Isosorbide - >98.0%(GC), high purity , CAS No.652-67-5 6 Citations
Basic Description Synonyms 1,4:3,6-Dianhydro-D-sorbitol | 1,4:3,6-Dianhydrosorbitol | BIDD:GT0695 | NSC40725 | NSC-40725 | D-Glucitol, 1,4:3,6-dianhydro- | EN300-170910 | D00347 | Dianhydro-D-glucitol | 1,4-Dianhydrosorbitol | Isosorbida (INN-Spanish) | Tox21_111861 | Glucitol, 1,4 Specifications & Purity ≥98%(GC) Biochemical and Physiological Mechanisms Osmotic diuretic agent. Nitric oxide donor. Shows vasodilatory, antihypertensive and diuretic effects in vivo. Orally active. Storage Temp Argon charged Shipped In Normal Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers Pubchem Sid 488181710 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488181710 IUPAC Name (3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol INCHI InChI=1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1 InChi Key KLDXJTOLSGUMSJ-JGWLITMVSA-N Canonical SMILES C1C(C2C(O1)C(CO2)O)O Isomeric SMILES C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O)O WGK Germany 2 RTECS LZ4380000 PubChem CID 12597 Molecular Weight 146.14 Beilstein 80510 Reaxy-Rn 80510
Chemical and Physical Properties Solubility Soluble in alcohols, water and ketones. Sensitivity Moisture sensitive Specific Rotation[α] 45° (C=5,H2O) Boil Point(°C) 175°C/2mmHg Melt Point(°C) 58-63℃
Safety and Hazards(GHS) WGK Germany 2 RTECS LZ4380000 Reaxy-Rn 80510 Merck Index 5224
Citations of This Product 1. Fukai Chu, Wei Wang, Yifan Zhou, Zhoumei Xu, Bin Zou, Xin Jiang, Yandong Hu, Weizhao Hu. (2023) Fully bio-based and intrinsically flame retardant unsaturated polyester cross-linked with isosorbide-based diluents. CHEMOSPHERE, 344 (15): (140371). [PMID:37820874 ] 2. Feng Caixing, Ma Haihong, Ren Fengmei, Zhou Zhengfa, Xu Weibing. (2023) Synthesis of fully bio-based branched unsaturated polyester oligomers and UV curing coatings. Journal of Coatings Technology and Research, 20 (5): (1747-1758). [PMID: 3. Danping Yuan, Fukui Xiao, Ning Zhao, Cunbao Deng, Xin Huang, Hao Zhang, Qianmin Yang, Yonggang Qiao. (2023) Mesoporous poly(ionic liquid) solid acid for sequential dehydration of sorbitol to isosorbide. CHEMICAL ENGINEERING JOURNAL, 460 (141780). [PMID: 4. Jiaying Gu, Ming Liu, Lin Li, Lulu Zhou, Lei He, Weijun Deng, Jing Hu. (2023) Osmanthus fragrance polyurethane/silk fibroin-based double-shell microcapsules for aromatic leather with sustained release fragrance. FLAVOUR AND FRAGRANCE JOURNAL, 38 (2): (73-82). [PMID: 5. Yinglu Sun, Xinxin Tian, Haopu Xie, Biru Shi, Jiahui Zhong, Xiangdong Liu, Yuming Yang. (2022) Reprocessable and degradable bio-based polyurethane by molecular design engineering with extraordinary mechanical properties for recycling carbon fiber. POLYMER, 258 (125313). [PMID: 6. Yong Li, Jiehao Qu, Zenghui Dai, Junyi Jiang, Jiajia Fu, Feiya Fu, Xiangdong Liu. (2022) Highly Bio-Based Unsaturated Polyester Resins with Improved Performance by Incorporating Isosorbide into the Polyester Prepolymer. MACROMOLECULAR MATERIALS AND ENGINEERING, 307 (9): (2200203). [PMID:
References 1. Fukai Chu, Wei Wang, Yifan Zhou, Zhoumei Xu, Bin Zou, Xin Jiang, Yandong Hu, Weizhao Hu. (2023) Fully bio-based and intrinsically flame retardant unsaturated polyester cross-linked with isosorbide-based diluents. CHEMOSPHERE, 344 (15): (140371). [PMID:37820874 ] 2. Feng Caixing, Ma Haihong, Ren Fengmei, Zhou Zhengfa, Xu Weibing. (2023) Synthesis of fully bio-based branched unsaturated polyester oligomers and UV curing coatings. Journal of Coatings Technology and Research, 20 (5): (1747-1758). [PMID: 3. Danping Yuan, Fukui Xiao, Ning Zhao, Cunbao Deng, Xin Huang, Hao Zhang, Qianmin Yang, Yonggang Qiao. (2023) Mesoporous poly(ionic liquid) solid acid for sequential dehydration of sorbitol to isosorbide. CHEMICAL ENGINEERING JOURNAL, 460 (141780). [PMID: 4. Jiaying Gu, Ming Liu, Lin Li, Lulu Zhou, Lei He, Weijun Deng, Jing Hu. (2023) Osmanthus fragrance polyurethane/silk fibroin-based double-shell microcapsules for aromatic leather with sustained release fragrance. FLAVOUR AND FRAGRANCE JOURNAL, 38 (2): (73-82). [PMID: 5. Yinglu Sun, Xinxin Tian, Haopu Xie, Biru Shi, Jiahui Zhong, Xiangdong Liu, Yuming Yang. (2022) Reprocessable and degradable bio-based polyurethane by molecular design engineering with extraordinary mechanical properties for recycling carbon fiber. POLYMER, 258 (125313). [PMID: 6. Yong Li, Jiehao Qu, Zenghui Dai, Junyi Jiang, Jiajia Fu, Feiya Fu, Xiangdong Liu. (2022) Highly Bio-Based Unsaturated Polyester Resins with Improved Performance by Incorporating Isosorbide into the Polyester Prepolymer. MACROMOLECULAR MATERIALS AND ENGINEERING, 307 (9): (2200203). [PMID:
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