Isosorbide - 10mM in DMSO, high purity , CAS No.652-67-5

6 Citations
  • 10mM in DMSO
Item Number
I425302
Grouped product items
SKUSizeAvailabilityPrice Qty
I425302-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90

Osmotic diuretic agent

Basic Description

Synonymsisosorbide | 652-67-5 | Isobide | Devicoran | Hydronol | Ismotic | Sorbid | (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol | (+)-D-Isosorbide | 1,4:3,6-Dianhydro-D-glucitol | 1,4-Dianhydrosorbitol | Vascardin dinitrate | Dianhydro-D-glucitol | D-Glucitol, 1,4:3,6-dianhydro- | AT
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsOsmotic diuretic agent. Nitric oxide donor. Shows vasodilatory, antihypertensive and diuretic effects in vivo. Orally active.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FTL Tbio Ferritin light chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KAT2A Tchem Histone acetyltransferase KAT2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PMP22 Tbio Peripheral myelin protein 22 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
THRB Tclin Thyroid hormone receptor beta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
INCHI InChI=1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1
InChi Key KLDXJTOLSGUMSJ-JGWLITMVSA-N
Canonical SMILES C1C(C2C(O1)C(CO2)O)O
Isomeric SMILES C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O)O
WGK Germany 2
RTECS LZ4380000
PubChem CID 12597
Molecular Weight 146.14
Beilstein 80510
Reaxy-Rn 80510

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SensitivityMoisture sensitive
Specific Rotation[α]45° (C=5,H2O)
Boil Point(°C)175°C/2mmHg
Melt Point(°C)58-63℃

Safety and Hazards(GHS)

WGK Germany 2
RTECS LZ4380000
Reaxy-Rn 80510
Merck Index 5224

Related Documents

Citations of This Product

1. Fukai Chu, Wei Wang, Yifan Zhou, Zhoumei Xu, Bin Zou, Xin Jiang, Yandong Hu, Weizhao Hu.  (2023)  Fully bio-based and intrinsically flame retardant unsaturated polyester cross-linked with isosorbide-based diluents.  CHEMOSPHERE,  344  (15): (140371).  [PMID:37820874]
2. Feng Caixing, Ma Haihong, Ren Fengmei, Zhou Zhengfa, Xu Weibing.  (2023)  Synthesis of fully bio-based branched unsaturated polyester oligomers and UV curing coatings.  Journal of Coatings Technology and Research,  20  (5): (1747-1758).  [PMID:]
3. Danping Yuan, Fukui Xiao, Ning Zhao, Cunbao Deng, Xin Huang, Hao Zhang, Qianmin Yang, Yonggang Qiao.  (2023)  Mesoporous poly(ionic liquid) solid acid for sequential dehydration of sorbitol to isosorbide.  CHEMICAL ENGINEERING JOURNAL,  460  (141780).  [PMID:]
4. Jiaying Gu, Ming Liu, Lin Li, Lulu Zhou, Lei He, Weijun Deng, Jing Hu.  (2023)  Osmanthus fragrance polyurethane/silk fibroin-based double-shell microcapsules for aromatic leather with sustained release fragrance.  FLAVOUR AND FRAGRANCE JOURNAL,  38  (2): (73-82).  [PMID:]
5. Yinglu Sun, Xinxin Tian, Haopu Xie, Biru Shi, Jiahui Zhong, Xiangdong Liu, Yuming Yang.  (2022)  Reprocessable and degradable bio-based polyurethane by molecular design engineering with extraordinary mechanical properties for recycling carbon fiber.  POLYMER,  258  (125313).  [PMID:]
6. Yong Li, Jiehao Qu, Zenghui Dai, Junyi Jiang, Jiajia Fu, Feiya Fu, Xiangdong Liu.  (2022)  Highly Bio-Based Unsaturated Polyester Resins with Improved Performance by Incorporating Isosorbide into the Polyester Prepolymer.  MACROMOLECULAR MATERIALS AND ENGINEERING,  307  (9): (2200203).  [PMID:]

References

1. Fukai Chu, Wei Wang, Yifan Zhou, Zhoumei Xu, Bin Zou, Xin Jiang, Yandong Hu, Weizhao Hu.  (2023)  Fully bio-based and intrinsically flame retardant unsaturated polyester cross-linked with isosorbide-based diluents.  CHEMOSPHERE,  344  (15): (140371).  [PMID:37820874]
2. Feng Caixing, Ma Haihong, Ren Fengmei, Zhou Zhengfa, Xu Weibing.  (2023)  Synthesis of fully bio-based branched unsaturated polyester oligomers and UV curing coatings.  Journal of Coatings Technology and Research,  20  (5): (1747-1758).  [PMID:]
3. Danping Yuan, Fukui Xiao, Ning Zhao, Cunbao Deng, Xin Huang, Hao Zhang, Qianmin Yang, Yonggang Qiao.  (2023)  Mesoporous poly(ionic liquid) solid acid for sequential dehydration of sorbitol to isosorbide.  CHEMICAL ENGINEERING JOURNAL,  460  (141780).  [PMID:]
4. Jiaying Gu, Ming Liu, Lin Li, Lulu Zhou, Lei He, Weijun Deng, Jing Hu.  (2023)  Osmanthus fragrance polyurethane/silk fibroin-based double-shell microcapsules for aromatic leather with sustained release fragrance.  FLAVOUR AND FRAGRANCE JOURNAL,  38  (2): (73-82).  [PMID:]
5. Yinglu Sun, Xinxin Tian, Haopu Xie, Biru Shi, Jiahui Zhong, Xiangdong Liu, Yuming Yang.  (2022)  Reprocessable and degradable bio-based polyurethane by molecular design engineering with extraordinary mechanical properties for recycling carbon fiber.  POLYMER,  258  (125313).  [PMID:]
6. Yong Li, Jiehao Qu, Zenghui Dai, Junyi Jiang, Jiajia Fu, Feiya Fu, Xiangdong Liu.  (2022)  Highly Bio-Based Unsaturated Polyester Resins with Improved Performance by Incorporating Isosorbide into the Polyester Prepolymer.  MACROMOLECULAR MATERIALS AND ENGINEERING,  307  (9): (2200203).  [PMID:]

Solution Calculators