ISRIB (trans-isomer) - 2mM in DMSO, high purity , CAS No.1597403-47-8

Item Number

I421913

Grouped product items
SKU	Size	Availability	Price	Qty
I421913-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$103.90

Potent and selective\xa0PERK\xa0inhibitor

Basic Description

Synonyms	ISRIB\|trans-ISRIB\|1597403-47-8\|548470-11-7\|ISRIB (trans-isomer)\|N,N'-(cis-Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide)\|1597403-48-9\|2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide\|N,N'-(Cyclohexane-1,4-diyl)bis(2-
Specifications & Purity	2mM in DMSO
Biochemical and Physiological Mechanisms	Potent and selective\xa0PERK\xa0inhibitor with\xa0IC 50 of 5 nM. Integrated stress response (ISR) inhibitor.
Storage Temp	Store at -80°C
Shipped In	Dry ice

Names and Identifiers

IUPAC Name	2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide
INCHI	InChI=1S/C22H24Cl2N2O4/c23-15-1-9-19(10-2-15)29-13-21(27)25-17-5-7-18(8-6-17)26-22(28)14-30-20-11-3-16(24)4-12-20/h1-4,9-12,17-18H,5-8,13-14H2,(H,25,27)(H,26,28)
InChi Key	HJGMCDHQPXTGAV-UHFFFAOYSA-N
Canonical SMILES	C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl
Isomeric SMILES	C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl
PubChem CID	1011240
Molecular Weight	451.34

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Basic Description