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Jaceosidin - 98%, high purity , CAS No.18085-97-7

≥98%

CAS#: 18085-97-7
Formula: C₁₇H₁₄O₇
Molecular Weight: 330.3
PubChem CID: 5379096

Item Number

J412635

Grouped product items
SKU	Size	Availability	Price
J412635-1mg	1mg	In stock	$35.90
J412635-5mg	5mg	In stock	$123.90
J412635-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$185.90
J412635-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$372.90
J412635-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$559.90
J412635-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$839.90

COX-2 Selective Inhibitors

Basic Description

Synonyms	Jaceosidin \| 18085-97-7 \| 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-chromen-4-one \| 4',5,7-Trihydroxy-3',6-dimethoxyflavone \| CHEBI:66103 \| 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy- \| 5U4Y68G678 \| 5,7-dihydroxy-2-(4-hy
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Jaceosidin, a flavonoid isolated from Artemisia vestita, possesses anti-tumor and anti-proliferative activities in many cancer cells. Jaceosidin induces apoptosis, activates Bax and down-regulates Mcl-1 and c-FLIP expression. Jaceosidin inhibits COX-2 exp
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information Jaceosidin, a flavonoid isolated from Artemisia vestita, possesses anti-tumor and anti-proliferative activities in many cancer cells. Jaceosidin inducesapoptosis, activatesBaxand down-regulatesMcl-1andc-FLIPexpression. Jaceosidin inhibitsCOX-2expression andNF-κBactivation. Targets Bax ; Mcl-1 ; c-FLIP ; COX-2 ; NF-κB

Associated Targets(Human)

APP Tclin Amyloid-beta A4 protein (8510 Activities)

Discover Target: APP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B2 Tchem Estradiol 17-beta-dehydrogenase 2 (1671 Activities)

Discover Target: HSD17B2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF-10A (2462 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THP-1 (11052 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS2R31 Tchem Taste receptor type 2 member 31 (86 Activities)

Discover Target: TAS2R31

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Nos2 Nitric oxide synthase, inducible (3573 Activities)

Discover Target: Nos2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PC-12 (7051 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxychromen-4-one
INCHI	InChI=1S/C17H14O7/c1-22-13-5-8(3-4-9(13)18)12-6-10(19)15-14(24-12)7-11(20)17(23-2)16(15)21/h3-7,18,20-21H,1-2H3
InChi Key	GLAAQZFBFGEBPS-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C=CC(=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)OC)O)O
Isomeric SMILES	COC1=C(C=CC(=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)OC)O)O
PubChem CID	5379096
Molecular Weight	330.3

Certificates

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8 results found

Lot Number	Certificate Type	Date	Item
K2329100	Certificate of Analysis	Nov 16, 2023	J412635
K2329101	Certificate of Analysis	Nov 16, 2023	J412635
K2329102	Certificate of Analysis	Nov 16, 2023	J412635
K2329142	Certificate of Analysis	Nov 16, 2023	J412635
K2329143	Certificate of Analysis	Nov 16, 2023	J412635
K2329144	Certificate of Analysis	Nov 16, 2023	J412635
K2329145	Certificate of Analysis	Nov 16, 2023	J412635
K2329146	Certificate of Analysis	Nov 16, 2023	J412635

Solubility

Solubility (25°C) In vitro DMSO: 66 mg/mL (199.82 mM); Water: Insoluble; Ethanol: 6 mg/mL

Melt Point(°C)

259-260°C

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