JAK2 Inhibitor IV - ≥97%, high purity , CAS No.1110502-30-1

  • ≥97%
Item Number
J339603
Grouped product items
SKUSizeAvailabilityPrice Qty
J339603-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$237.90

an inhibitor of JAK2

Basic Description

Specifications & Purity≥97%
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

JAK2 Inhibitor IV is an aminoindazole compound that potently inhibits the activity of both the wild-type JAK2 and the constitutively active V617F mutant. JAK2 Inhibitor IV shows much reduced activity against JAK3.

Product Properties

pKapKₐ: 11.9 (Predicted), pKₐ: 3.11 (Predicted)

Associated Targets(Human)

JAK3 Tclin Tyrosine-protein kinase JAK3 (8349 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
JAK2 Tclin Tyrosine-protein kinase JAK2 (12915 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Canonical SMILES CC(C)(C)NS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2)NN=C3N
Isomeric SMILES CC(C)(C)NS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2)NN=C3N
PubChem CID 24963047
Molecular Weight 344.43

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO (5 mg/ml), and ethanol (3 mg/ml).
Refractive Indexn20D1.65 (Predicted)
Boil Point(°C)594.41° C at 760 mmHg (Predicted)

Related Documents

Solution Calculators