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JAK2 Inhibitor IV - ≥97%, high purity , CAS No.1110502-30-1
Basic Description Specifications & Purity ≥97% Storage Temp Store at 2-8°C Shipped In Wet ice Product Description JAK2 Inhibitor IV is an aminoindazole compound that potently inhibits the activity of both the wild-type JAK2 and the constitutively active V617F mutant. JAK2 Inhibitor IV shows much reduced activity against JAK3.
Product Properties pKa pKₐ: 11.9 (Predicted), pKₐ: 3.11 (Predicted)
Associated Targets(Human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Canonical SMILES CC(C)(C)NS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2)NN=C3N Isomeric SMILES CC(C)(C)NS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2)NN=C3N PubChem CID 24963047 Molecular Weight 344.43
Chemical and Physical Properties Solubility Soluble in DMSO (5 mg/ml), and ethanol (3 mg/ml). Refractive Index n20D1.65 (Predicted) Boil Point(°C) 594.41° C at 760 mmHg (Predicted)
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