JNJ-38877605 - 98%, high purity , Hepatocyte growth factor receptor inhibitor, CAS No.943540-75-8, Hepatocyte growth factor receptor inhibitor

Item Number

J126347

• Synonyms: JNJ-38877605 | 943540-75-8 | JNJ38877605 | JNJ 38877605 | 6-(difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline | 6-[difluoro-[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline | 15UDG410PN | 6-(Difl
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: JNJ-38877605 is a c-MET inhibitor with an IC50 of 4 nM.Potent ATP-competitive inhibitor for the catalytic activity of c-Met (IC 50 = 4.7 nM). JNJ-38877605 inhibits c-Met with >833 fold selectivity relative to the next most potently inhibited kinase (Fms)
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Action Type: INHIBITOR
• Mechanism of action: Hepatocyte growth factor receptor inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.