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JNJ-65234637 , CAS No.J611274, Inhibitor of BCL6 transcription repressor

Item Number

J611274

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SKU	Size	Availability	Price	Qty
J611274-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
J611274-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,890.90

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Basic Description

Synonyms	compound 58;JNJ65234637;OICR-12694;OICR12694
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of BCL6 transcription repressor

BCL6 Tchem B-cell lymphoma 6 protein (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

INCHI	InChI=1S/C29H28ClF3N8O4/c1-13-10-38(2)6-7-40(13)19-9-17(22(30)26(33)36-19)35-20(42)12-39-11-16(14-8-15(27(34)44)25(43)24(32)23(14)31)21-28(39)37-18-4-3-5-41(18)29(21)45/h8-9,11,13,43H,3-7,10,12H2,1-2H3,(H2,34,44)(H,35,36,42)/t13-/m0/s1
InChi Key	LGAFZGSECXDYIR-ZDUSSCGKSA-N
Canonical SMILES	ClC=1C(=NC(=CC1NC(CN2C=C(C3=C2N=C4N(C3=O)CCC4)C=5C(=C(C(=C(C(=O)N)C5)O)F)F)=O)N6[C@H](CN(CC6)C)C)F
PubChem CID	156087292

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1. Mamai A, Chau AM, Wilson BJ, Watson ID, Joseph BB, Subramanian PR, Morshed MM, Morin JA, Prakesch MA, Lu T et al.. (2023) Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.. ACS Med Chem Lett, 14 (2): (199-210). [PMID:36793435] [10.1021/op500134e]

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