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JNJ-67856633 - 98%, high purity , CAS No.2230273-76-2, Inhibitor of Janus kinase 2;Inhibitor of MALT1 paracaspase

Moligand™

≥98%

CAS#: 2230273-76-2
Formula: C₂₀H₁₁F₆N₅O₂
Molecular Weight: 467.32
PubChem CID: 134609793

Item Number

J420001

Grouped product items
SKU	Size	Availability	Price
J420001-5mg	5mg	In stock	$137.90
J420001-10mg	10mg	In stock	$226.90
J420001-25mg	25mg	In stock	$434.90
J420001-50mg	50mg	In stock	$741.90
J420001-100mg	100mg	In stock	$1,236.90

View related series

Janus kinase 2 Inhibitor MALT1 MALT1 paracaspase Inhibitor Metabolic Enzyme/Protease NF-κB

Basic Description

Synonyms	APWRZPQBPCAXFP-UHFFFAOYSA-N \| SAFIMALTIB [INN] \| safimaltib \| SCHEMBL23417687 \| 1-(1-Oxo-1,2-dihydro-5-isoquinolyl)-5-(trifluoromethyl)-N-[2-(trifluoromethyl)-4-pyridyl]pyrazole-4-carboxamide \| GTPL11883 \| Safimaltib [WHO-DD] \| MFCD34475932 \| L9790S42AI \|
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of Janus kinase 2;Inhibitor of MALT1 paracaspase

Associated Targets(Human)

MALT1 Tchem Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (0 Activities)

Discover Target: MALT1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

JAK2 Tclin Tyrosine-protein kinase JAK2 (0 Activities)

Discover Target: JAK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	1-(1-oxo-2H-isoquinolin-5-yl)-5-(trifluoromethyl)-N-[2-(trifluoromethyl)pyridin-4-yl]pyrazole-4-carboxamide
INCHI	InChI=1S/C20H11F6N5O2/c21-19(22,23)15-8-10(4-6-27-15)30-18(33)13-9-29-31(16(13)20(24,25)26)14-3-1-2-12-11(14)5-7-28-17(12)32/h1-9H,(H,28,32)(H,27,30,33)
InChi Key	APWRZPQBPCAXFP-UHFFFAOYSA-N
Canonical SMILES	C1=CC2=C(C=CNC2=O)C(=C1)N3C(=C(C=N3)C(=O)NC4=CC(=NC=C4)C(F)(F)F)C(F)(F)F
Isomeric SMILES	C1=CC2=C(C=CNC2=O)C(=C1)N3C(=C(C=N3)C(=O)NC4=CC(=NC=C4)C(F)(F)F)C(F)(F)F
PubChem CID	134609793
Molecular Weight	467.32

CAS Registry No.

2230273-76-2

PubChem CID

134609793

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
G2227613	Certificate of Analysis	Jun 09, 2022	J420001
G2227614	Certificate of Analysis	Jun 09, 2022	J420001
G2227615	Certificate of Analysis	Jun 09, 2022	J420001
G2227616	Certificate of Analysis	Jun 09, 2022	J420001
G2227617	Certificate of Analysis	Jun 09, 2022	J420001

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.

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