JNJ40355003 - ≥98%, high purity , CAS No.1394894-41-7, Inhibitor of Fatty acid amide hydrolase

Item Number
J611266
Grouped product items
SKUSizeAvailabilityPrice Qty
J611266-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$166.90
J611266-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$666.90
J611266-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90
J611266-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90

Basic Description

SynonymsZ0O8PGE4TB | compound 23 [PMID: 24900385] | JNJ40355003 | JNJ-40355003 | UNII-Z0O8PGE4TB | AKOS040748632 | SCHEMBL1758816 | GTPL9050 | BDBM50394620 | CHEMBL2164602
Specifications & PurityMoligand™, ≥98%
Storage TempStore at 2-8°C,Protected from light
Shipped InWet ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of Fatty acid amide hydrolase
Product Description

JNJ-40355003 is a potent and selective atty acid amide hydrolase (FAAH) inhibitor.

Associated Targets(Human)

FAAH Tchem Fatty-acid amide hydrolase 1 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cynomolgus monkey (4946 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Brain (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-[[3-(4-chlorophenoxy)phenyl]methyl]-N-pyridin-3-ylpiperazine-1-carboxamide
INCHI InChI=1S/C23H23ClN4O2/c24-19-6-8-21(9-7-19)30-22-5-1-3-18(15-22)17-27-11-13-28(14-12-27)23(29)26-20-4-2-10-25-16-20/h1-10,15-16H,11-14,17H2,(H,26,29)
InChi Key CTYVKSQPMCSUOR-UHFFFAOYSA-N
Canonical SMILES Clc1ccc(cc1)Oc1cccc(c1)CN1CCN(CC1)C(=O)Nc1cccnc1
Isomeric SMILES C1CN(CCN1CC2=CC(=CC=C2)OC3=CC=C(C=C3)Cl)C(=O)NC4=CN=CC=C4
PubChem CID 46863664
Molecular Weight 422.91

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
J2409590Certificate of AnalysisJul 04, 2024 J611266
J2409591Certificate of AnalysisJul 04, 2024 J611266
J2409592Certificate of AnalysisJul 04, 2024 J611266
J2409593Certificate of AnalysisJul 04, 2024 J611266
J2409594Certificate of AnalysisJul 04, 2024 J611266
J2409730Certificate of AnalysisJul 04, 2024 J611266
J2409731Certificate of AnalysisJul 04, 2024 J611266
J2409732Certificate of AnalysisJul 04, 2024 J611266

Chemical and Physical Properties

SensitivityLight sensitive

Related Documents

Alternative Products

References

1. Keith JM, Apodaca R, Tichenor M, Xiao W, Jones W, Pierce J, Seierstad M, Palmer J, Webb M, Karbarz M et al..  (2012)  Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate..  ACS Med Chem Lett,  (10): (823-7).  [PMID:24900385] [10.1021/op500134e]

Solution Calculators