| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| J382462-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $360.90 |
a selective JNK1, JNK2, and JNK3 inhibitor
| Specifications & Purity | ≥95% |
|---|---|
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Product Description | JNK Inhibitor XIV is a cell-permeable and blood-brain-barrier-permeant anilinopyrimidine compound that acts as a highly selective, potent, reversible, and ATP-competitive JNK inhibitor (IC|50|= 67, 283, and 159 nM against JNK1, JNK2, and JNK3, respectively). |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| Canonical SMILES | CC1=NC=C(C=C1)C2=NN(C=N2)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC(=CC=C5)N6CCOCC6 |
|---|---|
| Isomeric SMILES | CC1=NC=C(C=C1)C2=NN(C=N2)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC(=CC=C5)N6CCOCC6 |
| PubChem CID | 57519510 |
| Molecular Weight | 490.56 |
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| Solubility | Soluble in DMSO. |
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