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Enzyme inhibitors and enzyme substrates
JZP 430 - ≥98%(HPLC), high purity , CAS No.1672691-74-5

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JZP 430 - ≥98%(HPLC), high purity , CAS No.1672691-74-5

≥98%(HPLC)

CAS#: 1672691-74-5
Formula: C₁₆H₂₆N₄O₃S
Molecular Weight: 354.47
PubChem CID: 121513897

Item Number

J287504

Grouped product items
SKU	Size	Availability	Price
J287504-10mg	10mg	In stock	$239.90
J287504-25mg	25mg	In stock	$479.90
J287504-50mg	50mg	In stock	$769.90
J287504-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,269.90

Potent and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor

Basic Description

Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent and irreversibleα/β-hydrolase domain 6 (ABHD6) inhibitor (IC50= 44 nM). Exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

ABHD6 Tchem Monoacylglycerol lipase ABHD6 (6 Activities)

Discover Target: ABHD6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MGLL Tchem Monoglyceride lipase (1909 Activities)

Discover Target: MGLL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl) N-cyclooctyl-N-methylcarbamate
INCHI	InChI=1S/C16H26N4O3S/c1-19(13-7-5-3-2-4-6-8-13)16(21)23-15-14(17-24-18-15)20-9-11-22-12-10-20/h13H,2-12H2,1H3
InChi Key	WKSHMJCYWFOADB-UHFFFAOYSA-N
Canonical SMILES	CN(C1CCCCCCC1)C(=O)OC2=NSN=C2N3CCOCC3
Isomeric SMILES	CN(C1CCCCCCC1)C(=O)OC2=NSN=C2N3CCOCC3
PubChem CID	121513897
Molecular Weight	354.47

Certificates

Certificate of Analysis(COA)

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7 results found

Lot Number	Certificate Type	Date	Item
L2304238	Certificate of Analysis	Nov 20, 2023	J287504
L2304239	Certificate of Analysis	Nov 20, 2023	J287504
L2304240	Certificate of Analysis	Nov 20, 2023	J287504
L2304244	Certificate of Analysis	Nov 20, 2023	J287504
L2304246	Certificate of Analysis	Nov 20, 2023	J287504
L2304247	Certificate of Analysis	Nov 20, 2023	J287504
L2304287	Certificate of Analysis	Nov 20, 2023	J287504

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 17.72, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 7.09, Max Conc. mM: 20

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