Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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K286853-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $75.90 | |
K286853-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $116.90 | |
K286853-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $262.90 | |
K286853-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $489.90 | |
K286853-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $880.90 | |
K286853-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,981.90 |
Amyloid fibril-specific fluorescent dye
Synonyms | CHEBI:78674 | SCHEMBL6374804 | DSSTox_GSID_25071 | CS-0027952 | SCHEMBL15093090 | (trans,trans)-1-bromo-2,5-bis-(4-hydroxy)styrylbenzene | 4-[(E)-2-[3-bromo-4-[(E)-2-(4-hydroxyphenyl)ethenyl]phenyl]ethenyl]phenol | Q27147905 | XJB20112 | K 114 | CHEBI:125 |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Potent amyloid fibril-specific fluorescent dye (EC50= 20 - 30 nM). Exhibits minimal fluorescence in aqueous buffers and fluoresces brightly in the presence of Aβ,α-synuclein and tauin situ. (Optimum wavelength = 550 nm). |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4-[(E)-2-[3-bromo-4-[(E)-2-(4-hydroxyphenyl)ethenyl]phenyl]ethenyl]phenol |
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INCHI | InChI=1S/C22H17BrO2/c23-22-15-18(2-1-16-5-11-20(24)12-6-16)4-10-19(22)9-3-17-7-13-21(25)14-8-17/h1-15,24-25H/b2-1+,9-3+ |
InChi Key | OXPHQQMZTXMEGO-RJTULKDBSA-N |
Canonical SMILES | C1=CC(=CC=C1C=CC2=CC(=C(C=C2)C=CC3=CC=C(C=C3)O)Br)O |
Isomeric SMILES | C1=CC(=CC=C1/C=C/C2=CC(=C(C=C2)/C=C/C3=CC=C(C=C3)O)Br)O |
PubChem CID | 44828481 |
Molecular Weight | 393.27 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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K2228001 | Certificate of Analysis | Oct 28, 2022 | K286853 |
K2228340 | Certificate of Analysis | Oct 28, 2022 | K286853 |
K2228372 | Certificate of Analysis | Oct 28, 2022 | K286853 |
K2228375 | Certificate of Analysis | Oct 28, 2022 | K286853 |
K2228377 | Certificate of Analysis | Oct 28, 2022 | K286853 |
K2228378 | Certificate of Analysis | Oct 28, 2022 | K286853 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 39.33, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 19.66, Max Conc. mM: 50 |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H413:May cause long lasting harmful effects to aquatic life |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. |