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K-Ras(GI2C) Inhibitor 9 - 98%, high purity , CAS No.1469337-91-4

Item Number
K350992
Grouped product items
SKUSizeAvailabilityPrice Qty
K350992-5mg
5mg
In stock
$332.90
K350992-10mg
10mg
In stock
$598.90
K350992-25mg
25mg
In stock
$1,346.90
K350992-50mg
50mg
In stock
$2,423.90
K350992-100mg
100mg
In stock
$4,363.90
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Basic Description

Specifications & PurityMoligand™, ≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™

Associated Targets(Human)

MRC5 (9203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H358 (882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-LU-1 (435 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H23 (49055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H2228 (1030 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H441 (233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KRAS Tclin GTPase KRas (1864 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488202301
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488202301
IUPAC Name N-[1-[2-(4-chloro-5-iodo-2-methoxyanilino)acetyl]piperidin-4-yl]ethenesulfonamide
INCHI InChI=1S/C16H21ClIN3O4S/c1-3-26(23,24)20-11-4-6-21(7-5-11)16(22)10-19-14-9-13(18)12(17)8-15(14)25-2/h3,8-9,11,19-20H,1,4-7,10H2,2H3
InChi Key ZGUSBCDCZNBNQT-UHFFFAOYSA-N
Canonical SMILES COC1=CC(=C(C=C1NCC(=O)N2CCC(CC2)NS(=O)(=O)C=C)I)Cl
Isomeric SMILES COC1=CC(=C(C=C1NCC(=O)N2CCC(CC2)NS(=O)(=O)C=C)I)Cl
PubChem CID 71761630
Molecular Weight 513.78

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
C23181341Certificate of AnalysisDec 14, 2022 K350992
C23181342Certificate of AnalysisDec 14, 2022 K350992
C23181345Certificate of AnalysisDec 14, 2022 K350992
C23181346Certificate of AnalysisDec 14, 2022 K350992
C23181347Certificate of AnalysisDec 14, 2022 K350992
C23181348Certificate of AnalysisDec 14, 2022 K350992
C23181369Certificate of AnalysisDec 14, 2022 K350992
C23181370Certificate of AnalysisDec 14, 2022 K350992
C23181371Certificate of AnalysisDec 14, 2022 K350992
C23181372Certificate of AnalysisDec 14, 2022 K350992

Related Documents

 SDS

 Specification Sheet

References

1. Ostrem JM, Peters U, Sos ML, Wells JA, Shokat KM.  (2013)  K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions..  Nature,  503  (7477): (548-51).  [PMID:24256730]

Solution Calculators

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