Kaempferol-3-O-neohesperidoside - 95%, high purity , CAS No.32602-81-6

  • ≥95%
Item Number
K412880
Grouped product items
SKUSizeAvailabilityPrice Qty
K412880-1mg
1mg
In stock
$59.90
K412880-5mg
5mg
In stock
$246.90
K412880-10mg
10mg
In stock
$395.90
K412880-25mg
25mg
In stock
$891.90
K412880-50mg
50mg
In stock
$1,603.90

Carbohydrate Metabolism Modulators

Basic Description

SynonymsMS-30567 | 3-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | s5468 | CHEBI:185334 | kaempferol
Specifications & Purity≥95%
Biochemical and Physiological MechanismsKaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid isolated from the leaf extract of Primula latifolia Lapeyr. and Primula vulgaris Hudson, stimulates glycogen synthesis in rat soleus muscle via PI3K - GSK-3 pathway and MAPK - PP
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

Kaempferol-3-O-neohesperidoside Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid isolated from the leaf extract of Primula latifolia Lapeyr. and Primula vulgaris Hudson, stimulates glycogen synthesis in rat soleus muscle via PI3K - GSK-3 pathway and MAPK - PP1 pathway.


Targets

PI3K ; GSK-3 ; MAPK ; PP1

Product Properties

ALogP-0.916
HBD Count9
Rotatable Bond6

Associated Targets(Human)

PANC-1 (6144 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-2 (46422 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-OV-3 (52876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

C6 (2371 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BV-2 (3710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
INCHI InChI=1S/C27H30O15/c1-9-17(32)20(35)22(37)26(38-9)42-25-21(36)18(33)15(8-28)40-27(25)41-24-19(34)16-13(31)6-12(30)7-14(16)39-23(24)10-2-4-11(29)5-3-10/h2-7,9,15,17-18,20-22,25-33,35-37H,8H2,1H3/t9-,15+,17-,18+,20+,21-,22+,25+,26-,27-/m0/s1
InChi Key OHOBPOYHROOXEI-JWMUNMLDSA-N
Canonical SMILES CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)CO)O)O)O)O)O
Isomeric SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)CO)O)O)O)O)O
PubChem CID 5318761
Molecular Weight 594.52

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
I2227274Certificate of AnalysisJul 29, 2022 K412880
I2227276Certificate of AnalysisJul 29, 2022 K412880
I2227466Certificate of AnalysisJul 29, 2022 K412880
I2227498Certificate of AnalysisJul 29, 2022 K412880
I2227500Certificate of AnalysisJul 29, 2022 K412880

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 100 mg/mL (168.2 mM);    
Sensitivitylight sensitive
DMSO(mg / mL) Max Solubility100
DMSO(mM) Max Solubility168.202920002691
Water(mg / mL) Max Solubility-1

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P337+P313:IF eye irritation persists: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P332+P313:IF SKIN irritation occurs: Get medical advice/attention.

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