Determine the necessary mass, volume, or concentration for preparing a solution.
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Synonyms | kaempferol | 520-18-3 | Robigenin | Kaempherol | Kempferol | Populnetin | Rhamnolutein | Trifolitin | Swartziol | Pelargidenolon | Rhamnolutin | 3,4',5,7-Tetrahydroxyflavone | Indigo Yellow | Kampherol | Campherol | Kampferol | Nimbecetin | 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen- |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | Description: IC50 value: Kaempferol inhibits proliferation of ovarian cancer cells at 40μM or higher concentrations[2]. Kaempferol (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) is a relatively common nontoxic, natural di |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
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INCHI | InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H |
InChi Key | IYRMWMYZSQPJKC-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O |
Isomeric SMILES | C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O |
RTECS | LK9275200 |
PubChem CID | 5280863 |
Molecular Weight | 286.24 |
Beilstein | 304401 |
Reaxy-Rn | 304401 |
Enter Lot Number to search for COA:
Sensitivity | light sensitive;Air sensitive |
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Melt Point(°C) | 276°C |
Pictogram(s) | GHS06, GHS08 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H341:Suspected of causing genetic defects |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. |
RTECS | LK9275200 |
Reaxy-Rn | 304401 |
Merck Index | 5274 |
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5. Hao-Xiang Gao, Nan Chen, Qiang He, Bi Shi, Wei-Cai Zeng. (2024) Effects of structural characteristics of phenolic compounds on oxidation of glycerol trioleate: Action rule and mechanism. FOOD CHEMISTRY, 433 (137361). [PMID:37688816] [10.1016/j.foodchem.2023.137361] |
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10. Qiaozhi Zhang, Shiyu Fan, Hujun Xie, Yan Zhang, Linglin Fu. (2023) Polyphenols from pigmented quinoa as potential modulators of maize starch digestion: Role of the starch-polyphenol inclusion and non-inclusion complexes. FOOD HYDROCOLLOIDS, 144 (108975). [PMID:] [10.1016/j.foodhyd.2023.108975] |
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13. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang. (2023) Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF. Analytical Methods, 15 (24): (2964-2970). [PMID:37309583] [10.1039/D3AY00486D] |
14. Xiangrong Li, Ruonan Xu, Tianjun Ni. (2023) Effects of B-ring structures on binding behavior of flavonols with proteins: Experimental and molecular docking approaches. JOURNAL OF MOLECULAR STRUCTURE, 1287 (135614). [PMID:] [10.1016/j.molstruc.2023.135614] |
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18. Lin Xiao, Wenna Ma, Jiarong Zhang, Xiaojun Pu, Zed Rengel, Zhongbang Song, Qi Chen. (2023) Phytomelatonin interferes with flavonols biosynthesis to regulate ROS production and stomatal closure in tobacco. JOURNAL OF PLANT PHYSIOLOGY, 284 (153977). [PMID:37062233] [10.1016/j.jplph.2023.153977] |
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20. Jiabin Zhou, Yuhan Liu, Jun Chen, Nanxiang Xiong, Dongye Yi. (2023) Kaempferol suppresses glioma progression and synergistically enhances the antitumor activity of gefitinib by inhibiting the EGFR/SRC/STAT3 signaling pathway. DRUG DEVELOPMENT RESEARCH, 84 (3): (582-600). [PMID:36852868] [10.1002/ddr.22048] |
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25. Hongting Deng, Yuanju He, Hui Cao, Lei Chen, Hui Teng. (2022) New insight into the effect of hydroxyl substituted flavonoids on the cytotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline. Food Frontiers, 4 (1): (289-296). [PMID:] [10.1002/fft2.194] |
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30. Xiangrong Li, Linyu Han, Zhizhi Song, Ruonan Xu, Lixia Wang. (2023) Comparative study on the interaction between transferrin and flavonols: Experimental and computational modeling approaches. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 288 (122128). [PMID:36455462] [10.1016/j.saa.2022.122128] |
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