Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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K103026-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $230.90 |
Aminoglycoside antibiotic agent
Synonyms | Kanamycin sulfate | 25389-94-0 | Kanamycin A sulfate | Kanamycin monosulfate | Kanamycin acid sulfate | Kanamycin (sulfate) | Kanamycin A sulphate | Ophtalmokalixan | 133-92-6 | Kanamycin Monosulphate | 3847-27-6 | J80EX28SMQ | Kanamycin monosulfate [JAN] | Kanamycin A monosulfate |
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Specifications & Purity | analytical standard |
Biochemical and Physiological Mechanisms | Kanamycin (also known as kanamycin A) is an aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. Kanamycin may cause |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid |
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INCHI | InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1 |
InChi Key | OOYGSFOGFJDDHP-KMCOLRRFSA-N |
Canonical SMILES | C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O |
Isomeric SMILES | C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N.OS(=O)(=O)O |
RTECS | NZ3225030 |
Alternate CAS | 70560-51-9 |
PubChem CID | 441374 |
UN Number | 2811 |
Packing Group | III |
Molecular Weight | 582.58 |
Beilstein | 18(4)7631 |
Reaxy-Rn | 3874279 |
Enter Lot Number to search for COA:
Specific Rotation[α] | 117.5 ° (C=1, H2O) |
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Melt Point(°C) | 250°C(dec.)(lit.) |
Pictogram(s) | GHS08 |
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Signal | Danger |
Hazard Statements | H360:May damage fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
RTECS | NZ3225030 |
Reaxy-Rn | 3874279 |
Class | 6.1 |
Merck Index | 5281 |
1. Jingzhi Yang, Yami Ran, Shaopeng Liu, Chenhao Ren, Yuntian Lou, Pengfei Ju, Guoliang Li, Xiaogang Li, Dawei Zhang. (2023) Synergistic D-Amino Acids Based Antimicrobial Cocktails Formulated via High-Throughput Screening and Machine Learning. Advanced Science, 11 (9): (2307173). [PMID:38126652] |
2. Jun Yao. (2024) A multiple signal amplification photoelectrochemical biosensor based on biotin-avidin system for kanamycin sensing in fish and milk via synergism of g-C3N4 and Ru@SiO2. ANALYTICA CHIMICA ACTA, 1288 (342141). [PMID:38220276] |
3. Yin Bao, Kaiwei Cai, Yichen Liu, Bingling Li. (2023) Aptamer-Based Antibiotic Electrochemical Detection Platform Using Portable Plastic Gold Electrode and Multichannel Chip. CHINESE JOURNAL OF CHEMISTRY, (4): [PMID:16990800] |
4. Pei Jia, Qiushuang Wu, Boyang Sun, Li Wang. (2023) Formic Acid-Regulated Defect Engineering in Zr-Based Metal-Organic Frameworks toward Fluorescence Sensor for Sensitive Detection of Chlortetracycline. Small, 19 (45): (2304096). [PMID:37415537] |
5. Mingcong Rong, Yi Huang, Xiaoting Zhuang, Yingming Ma, Haijiao Xie, Yanfang Wu, Li Niu. (2023) AND logic-gate-based Au@MnO2 sensing platform for tetracyclines with fluorescent and colorimetric dual-signal readouts. SENSORS AND ACTUATORS B-CHEMICAL, 393 (134204). [PMID:] |
6. Yang Zhenhua, Yang Xintong, Zhang Yuexia, Fan Xiaopeng, Cao Yujuan, Li Zhongping, Dong Chuan. (2023) Detection of oxytetracycline in milk using a novel carbon dots-based fluorescence probe via facile pyrolysis synthesis. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (35): (84002-84010). [PMID:37353701] |
7. Jianan Li, Wenjie Huang, Huixia He, Shuangni Shi, Xiuxia Sun, Jianxi Xiao. (2023) Biocompatible and bioactive hydrogels of recombinant fusion elastin with low transition temperature for improved healing of UV-irradiated skin. Journal of Materials Chemistry B, [PMID:37401183] |
8. Yafang Liu, Ming Yi, Yan Wang. (2023) Boronate ester-based pH stimulated bactericide armoring for efficient fouling control of LNF membranes. JOURNAL OF MEMBRANE SCIENCE, 678 (121662). [PMID:] |
9. Jing Han, Pengfei Ma, Imran Mahmood Khan, Yin Zhang, Zhouping Wang. (2023) Study of binding mechanism of aptamer to kanamycin and the development of fluorescent aptasensor in milk detection. TALANTA, 260 (124530). [PMID:37116356] |
10. Ming Yi, Thi Dao Nguyen, Huan Liu, Yafang Liu, Shu Xiong, Yan Wang. (2023) A Boronate Ester Driven Rechargeable Antibacterial Membrane for Fast Molecular Sieving. ADVANCED FUNCTIONAL MATERIALS, 33 (26): (2213471). [PMID:] |
11. Wanling Cui, Jinrong Liu, Wenqi Zhao, Jiayi Zhang, Yanyan Wang, Qiang Li, Rui Wang, Mei Qiao, Shicai Xu. (2023) An enzyme-free and label-free fluorescent aptasensor for sensitive detection of kanamycin in milk samples based on hybridization chain reaction. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 120 (105300). [PMID:] |
12. Zhen-Ping Zou, Yue Du, Ting-Ting Fang, Ying Zhou, Bang-Ce Ye. (2023) Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice. Cell Host & Microbe, 31 (199-212.e5). [PMID:36758520] |
13. Baizhu Chen, Xiaoge Zhang, Lili Cheng, Xiaomei Chen, Junjie Tang, Peng Zhang, Chen Wang, Jie Liu. (2023) Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy. JOURNAL OF CONTROLLED RELEASE, 353 (889). [PMID:36528194] |
14. Jian Song, Kaiyu He, Bingcong Xing, Yong Pei, Dingnan Wang, Yang Wang, Shiyan Li, Jie Li, Weiwei Huan, Yiming Zhang, Bruce. D. Hammock. (2022) Rapid Measurement of Residual Kanamycin Using Highly Specific Biomimetic Recognition Paper-Based Chip. ANALYTICAL CHEMISTRY, 94 (50): (17567–17576). [PMID:36458677] |
15. Qingbin Yuan, Pingfeng Yu, Yuan Cheng, Pengxiao Zuo, Yisi Xu, Yuxiao Cui, Yi Luo, Pedro J. J. Alvarez. (2022) Chlorination (but Not UV Disinfection) Generates Cell Debris that Increases Extracellular Antibiotic Resistance Gene Transfer via Proximal Adsorption to Recipients and Upregulated Transformation Genes. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 56 (23): (17166–17176). [PMID:36286344] |
16. Ying Liu, Jingfeng Gao, Mingyan Zhao, Xiaoyu Fu, Yi Zhang, Haoran Zhang. (2023) Removal of antibiotic resistant bacteria, genes and inhibition of plasmid-mediated horizontal transfer by peroxymonosulfate: Efficiency and mechanisms. CHEMICAL ENGINEERING JOURNAL, 453 (139728). [PMID:] |
17. Yi Zhang, Qingbo Deng, Chang Tang, Minglu Zhang, Zilong Huang, Zhifeng Cai. (2023) Fluorescent folic acid-capped copper nanoclusters for the determination of rifampicin based on inner filter effect. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 286 (121944). [PMID:36228492] |
18. Hui Yang, Yunlong Wei, Xiufang Yan, Chao Nie, Zhenchun Sun, Likai Hao, Xiankun Su. (2022) High-Efficiency Utilization of Waste Tobacco Stems to Synthesize Novel Biomass-Based Carbon Dots for Precise Detection of Tetracycline Antibiotic Residues. Nanomaterials, 12 (18): (3241). [PMID:36145029] |
19. Zishuo Zhang, Yuanyuan Wang, Ziyin Mei, Yiming Wang, Hui Li, Shaoguang Li, Fan Xia. (2022) Incorporating Hydrophobic Moieties into Self-Assembled Monolayers to Enable Electrochemical Aptamer-Based Sensors Deployed Directly in a Complex Matrix. ACS Sensors, 7 (9): (2615–2624). [PMID:35998663] |
20. Yuhua Zhang, Qiaojun Fang, Hongfeng Wang, Jieyu Qi, Shan Sun, Menghui Liao, Yunhao Wu, Yangnan Hu, Pei Jiang, Cheng Cheng, Xiaoyun Qian, Mingliang Tang, Wei Cao, Shang Xiang, Chen Zhang, Jianming Yang, Xia Gao, Zheng Ying, Renjie Chai. (2023) Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage. Autophagy, 19 (1): (75-91). [PMID:35471096] |
21. Wang Yang, Jin Daobin, Zhang Xiaoqian, Zhao Jikuan, Hun Xu. (2022) Self-enhancement photoelectrochemical strategy for kanamycin determination with amino functionalized MOFs. MICROCHIMICA ACTA, 189 (5): (1-7). [PMID:35426050] |
22. Zhiwen Li, Jiyue Zhang, Qiyao Sun, Wenwen Shi, Tingxian Tao, Yingqiang Fu. (2022) Moxifloxacin detection based on fluorescence resonance energy transfer from carbon quantum dots to moxifloxacin using a ratiometric fluorescence probe. NEW JOURNAL OF CHEMISTRY, 46 (9): (4226-4232). [PMID:] |
23. Xuelian Hu, Ying Guo, Jinni Zhang, Xiaohui Wang, Guozhen Fang, Shuo Wang. (2022) A signal-amplified ratiometric fluorescence biomimetic sensor based on the synergistic effect of IFE and AE for the visual smart monitoring of oxytetracycline. CHEMICAL ENGINEERING JOURNAL, 433 (134499). [PMID:] |
24. Zhou Li-Jian, Guo Li-Bin, Wei Wei, Lv Zhi-Xiang, Zhang Ye-Wang. (2021) A Novel Chondroitin AC Lyase With Broad Substrate Specificity From Pedobacter rhizosphaerae: Cloning, Expression, and Characterization. Frontiers in Bioengineering and Biotechnology, 9 (1336). [PMID:35004658] |
25. Qi Nie, Jingjing Deng, Bing Xie, Guoyue Shi, Tianshu Zhou. (2021) A dual-channel colorimetric and fluorescent sensor for the rapid and ultrasensitive detection of kanamycin based on gold nanoparticles-copper nanoclusters. Analytical Methods, 13 (48): (5813-5820). [PMID:34852031] |
26. Wanling Cui, Guodong Hu, Enguang Lv, Chonghui Li, Zhenxing Wang, Qiang Li, Zhaohong Qian, Jihua Wang, Shicai Xu, Rui Wang. (2022) A label-free and enzyme-free fluorescent aptasensor for amplified detection of kanamycin in milk sample based on target-triggered catalytic hairpin assembly. FOOD CONTROL, 133 (108654). [PMID:] |
27. Yimeng Sun, Cong Ma, Man Wu, Chunping Jia, Shilun Feng, Jianlong Zhao, Lijuan Liang. (2022) Sensitivity of photoelctrocehmical aptasensor using spiral nanorods for detecting antiobiotic levels in experimental and real samples. TALANTA, 237 (122930). [PMID:34736667] |
1. Jingzhi Yang, Yami Ran, Shaopeng Liu, Chenhao Ren, Yuntian Lou, Pengfei Ju, Guoliang Li, Xiaogang Li, Dawei Zhang. (2023) Synergistic D-Amino Acids Based Antimicrobial Cocktails Formulated via High-Throughput Screening and Machine Learning. Advanced Science, 11 (9): (2307173). [PMID:38126652] |
2. Jun Yao. (2024) A multiple signal amplification photoelectrochemical biosensor based on biotin-avidin system for kanamycin sensing in fish and milk via synergism of g-C3N4 and Ru@SiO2. ANALYTICA CHIMICA ACTA, 1288 (342141). [PMID:38220276] |
3. Yin Bao, Kaiwei Cai, Yichen Liu, Bingling Li. (2023) Aptamer-Based Antibiotic Electrochemical Detection Platform Using Portable Plastic Gold Electrode and Multichannel Chip. CHINESE JOURNAL OF CHEMISTRY, (4): [PMID:16990800] |
4. Pei Jia, Qiushuang Wu, Boyang Sun, Li Wang. (2023) Formic Acid-Regulated Defect Engineering in Zr-Based Metal-Organic Frameworks toward Fluorescence Sensor for Sensitive Detection of Chlortetracycline. Small, 19 (45): (2304096). [PMID:37415537] |
5. Mingcong Rong, Yi Huang, Xiaoting Zhuang, Yingming Ma, Haijiao Xie, Yanfang Wu, Li Niu. (2023) AND logic-gate-based Au@MnO2 sensing platform for tetracyclines with fluorescent and colorimetric dual-signal readouts. SENSORS AND ACTUATORS B-CHEMICAL, 393 (134204). [PMID:] |
6. Yang Zhenhua, Yang Xintong, Zhang Yuexia, Fan Xiaopeng, Cao Yujuan, Li Zhongping, Dong Chuan. (2023) Detection of oxytetracycline in milk using a novel carbon dots-based fluorescence probe via facile pyrolysis synthesis. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (35): (84002-84010). [PMID:37353701] |
7. Jianan Li, Wenjie Huang, Huixia He, Shuangni Shi, Xiuxia Sun, Jianxi Xiao. (2023) Biocompatible and bioactive hydrogels of recombinant fusion elastin with low transition temperature for improved healing of UV-irradiated skin. Journal of Materials Chemistry B, [PMID:37401183] |
8. Yafang Liu, Ming Yi, Yan Wang. (2023) Boronate ester-based pH stimulated bactericide armoring for efficient fouling control of LNF membranes. JOURNAL OF MEMBRANE SCIENCE, 678 (121662). [PMID:] |
9. Jing Han, Pengfei Ma, Imran Mahmood Khan, Yin Zhang, Zhouping Wang. (2023) Study of binding mechanism of aptamer to kanamycin and the development of fluorescent aptasensor in milk detection. TALANTA, 260 (124530). [PMID:37116356] |
10. Ming Yi, Thi Dao Nguyen, Huan Liu, Yafang Liu, Shu Xiong, Yan Wang. (2023) A Boronate Ester Driven Rechargeable Antibacterial Membrane for Fast Molecular Sieving. ADVANCED FUNCTIONAL MATERIALS, 33 (26): (2213471). [PMID:] |
11. Wanling Cui, Jinrong Liu, Wenqi Zhao, Jiayi Zhang, Yanyan Wang, Qiang Li, Rui Wang, Mei Qiao, Shicai Xu. (2023) An enzyme-free and label-free fluorescent aptasensor for sensitive detection of kanamycin in milk samples based on hybridization chain reaction. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 120 (105300). [PMID:] |
12. Zhen-Ping Zou, Yue Du, Ting-Ting Fang, Ying Zhou, Bang-Ce Ye. (2023) Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice. Cell Host & Microbe, 31 (199-212.e5). [PMID:36758520] |
13. Baizhu Chen, Xiaoge Zhang, Lili Cheng, Xiaomei Chen, Junjie Tang, Peng Zhang, Chen Wang, Jie Liu. (2023) Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy. JOURNAL OF CONTROLLED RELEASE, 353 (889). [PMID:36528194] |
14. Jian Song, Kaiyu He, Bingcong Xing, Yong Pei, Dingnan Wang, Yang Wang, Shiyan Li, Jie Li, Weiwei Huan, Yiming Zhang, Bruce. D. Hammock. (2022) Rapid Measurement of Residual Kanamycin Using Highly Specific Biomimetic Recognition Paper-Based Chip. ANALYTICAL CHEMISTRY, 94 (50): (17567–17576). [PMID:36458677] |
15. Qingbin Yuan, Pingfeng Yu, Yuan Cheng, Pengxiao Zuo, Yisi Xu, Yuxiao Cui, Yi Luo, Pedro J. J. Alvarez. (2022) Chlorination (but Not UV Disinfection) Generates Cell Debris that Increases Extracellular Antibiotic Resistance Gene Transfer via Proximal Adsorption to Recipients and Upregulated Transformation Genes. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 56 (23): (17166–17176). [PMID:36286344] |
16. Ying Liu, Jingfeng Gao, Mingyan Zhao, Xiaoyu Fu, Yi Zhang, Haoran Zhang. (2023) Removal of antibiotic resistant bacteria, genes and inhibition of plasmid-mediated horizontal transfer by peroxymonosulfate: Efficiency and mechanisms. CHEMICAL ENGINEERING JOURNAL, 453 (139728). [PMID:] |
17. Yi Zhang, Qingbo Deng, Chang Tang, Minglu Zhang, Zilong Huang, Zhifeng Cai. (2023) Fluorescent folic acid-capped copper nanoclusters for the determination of rifampicin based on inner filter effect. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 286 (121944). [PMID:36228492] |
18. Hui Yang, Yunlong Wei, Xiufang Yan, Chao Nie, Zhenchun Sun, Likai Hao, Xiankun Su. (2022) High-Efficiency Utilization of Waste Tobacco Stems to Synthesize Novel Biomass-Based Carbon Dots for Precise Detection of Tetracycline Antibiotic Residues. Nanomaterials, 12 (18): (3241). [PMID:36145029] |
19. Zishuo Zhang, Yuanyuan Wang, Ziyin Mei, Yiming Wang, Hui Li, Shaoguang Li, Fan Xia. (2022) Incorporating Hydrophobic Moieties into Self-Assembled Monolayers to Enable Electrochemical Aptamer-Based Sensors Deployed Directly in a Complex Matrix. ACS Sensors, 7 (9): (2615–2624). [PMID:35998663] |
20. Yuhua Zhang, Qiaojun Fang, Hongfeng Wang, Jieyu Qi, Shan Sun, Menghui Liao, Yunhao Wu, Yangnan Hu, Pei Jiang, Cheng Cheng, Xiaoyun Qian, Mingliang Tang, Wei Cao, Shang Xiang, Chen Zhang, Jianming Yang, Xia Gao, Zheng Ying, Renjie Chai. (2023) Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage. Autophagy, 19 (1): (75-91). [PMID:35471096] |
21. Wang Yang, Jin Daobin, Zhang Xiaoqian, Zhao Jikuan, Hun Xu. (2022) Self-enhancement photoelectrochemical strategy for kanamycin determination with amino functionalized MOFs. MICROCHIMICA ACTA, 189 (5): (1-7). [PMID:35426050] |
22. Zhiwen Li, Jiyue Zhang, Qiyao Sun, Wenwen Shi, Tingxian Tao, Yingqiang Fu. (2022) Moxifloxacin detection based on fluorescence resonance energy transfer from carbon quantum dots to moxifloxacin using a ratiometric fluorescence probe. NEW JOURNAL OF CHEMISTRY, 46 (9): (4226-4232). [PMID:] |
23. Xuelian Hu, Ying Guo, Jinni Zhang, Xiaohui Wang, Guozhen Fang, Shuo Wang. (2022) A signal-amplified ratiometric fluorescence biomimetic sensor based on the synergistic effect of IFE and AE for the visual smart monitoring of oxytetracycline. CHEMICAL ENGINEERING JOURNAL, 433 (134499). [PMID:] |
24. Zhou Li-Jian, Guo Li-Bin, Wei Wei, Lv Zhi-Xiang, Zhang Ye-Wang. (2021) A Novel Chondroitin AC Lyase With Broad Substrate Specificity From Pedobacter rhizosphaerae: Cloning, Expression, and Characterization. Frontiers in Bioengineering and Biotechnology, 9 (1336). [PMID:35004658] |
25. Qi Nie, Jingjing Deng, Bing Xie, Guoyue Shi, Tianshu Zhou. (2021) A dual-channel colorimetric and fluorescent sensor for the rapid and ultrasensitive detection of kanamycin based on gold nanoparticles-copper nanoclusters. Analytical Methods, 13 (48): (5813-5820). [PMID:34852031] |
26. Wanling Cui, Guodong Hu, Enguang Lv, Chonghui Li, Zhenxing Wang, Qiang Li, Zhaohong Qian, Jihua Wang, Shicai Xu, Rui Wang. (2022) A label-free and enzyme-free fluorescent aptasensor for amplified detection of kanamycin in milk sample based on target-triggered catalytic hairpin assembly. FOOD CONTROL, 133 (108654). [PMID:] |
27. Yimeng Sun, Cong Ma, Man Wu, Chunping Jia, Shilun Feng, Jianlong Zhao, Lijuan Liang. (2022) Sensitivity of photoelctrocehmical aptasensor using spiral nanorods for detecting antiobiotic levels in experimental and real samples. TALANTA, 237 (122930). [PMID:34736667] |