| 1. Zeng L, Yap KL, Ivanov AV, Wang X, Mujtaba S, Plotnikova O, Rauscher FJ, Zhou MM. (2008) Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing.. Nat Struct Mol Biol, 15 (6): (626-33). [PMID:18488044] |
| 2. Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C et al.. (2007) Patterns of somatic mutation in human cancer genomes.. Nature, 446 (7132): (153-8). [PMID:17344846] |
| 3. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions.. Science, 325 (5942): (834-40). [PMID:19608861] |
| 4. Tan L, Gurbani D, Weisberg EL, Jones DS, Rao S, Singer WD, Bernard FM, Mowafy S, Jenney A, Du G et al.. (2017) Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors.. Bioorg Med Chem, 25 (4): (1320-1328). [PMID:28038940] |
| 5. Francis Impens,Lilliana Radoshevich,Pascale Cossart,David Ribet. (2014-08-13) Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.. Proceedings of the National Academy of Sciences of the United States of America, 111 ((34)): (12432-12437). [PMID:25114211] |
| 6. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330] |
| 7. Chen P, Chaikuad A, Bamborough P, Bantscheff M, Bountra C, Chung CW, Fedorov O, Grandi P, Jung D, Lesniak R, Lindon M, Müller S, Philpott M, Prinjha R, Rogers C, Selenski C, Tallant C, Werner T, Willson TM, Knapp S, Drewry DH.. (2016) Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.. J Med Chem, 59 (4): (1410-1424). [PMID:25799074] |
| 8. Crane EA, Heydenreuter W, Beck KR, Strajhar P, Vomacka J, Smiesko M, Mons E, Barth L, Neuburger M, Vedani A, Odermatt A, Sieber SA, Gademann K.. (2019) Profiling withanolide A for therapeutic targets in neurodegenerative diseases.. Bioorg Med Chem, 27 (12): (2508-2520). [PMID:30929949] |
| 9. Friedman, J R JR and 6 more authors.. (1996) KAP-1, a novel corepressor for the highly conserved KRAB repression domain.. Genes & development, (15): [PMID:8769649] |
| 10. Moosmann, P P, Georgiev, O O, Le Douarin, B B, Bourquin, J P JP and Schaffner, W W.. (1996) Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1.. Nucleic acids research, (15): [PMID:9016654] |
| 11. Ryan, R F RF and 6 more authors.. (1999) KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.. Molecular and cellular biology, [PMID:10330177] |
| 12. Agata, Y Y, Matsuda, E E and Shimizu, A A.. (1999) Two novel Krüppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1beta/KRIP-1).. The Journal of biological chemistry, (4): [PMID:10347202] |
| 13. Underhill, C C, Qutob, M S MS, Yee, S P SP and Torchia, J J.. (2000) A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.. The Journal of biological chemistry, (22): [PMID:11013263] |
| 14. Capili, A D AD, Schultz, D C DC, RauscherIII, F J FJ and Borden, K L KL.. (2001) Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains.. The EMBO journal, (15): [PMID:11226167] |
| 15. Schultz, D C DC, Friedman, J R JR and Rauscher, F J FJ.. (2001) Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD.. Genes & development, (15): [PMID:11230151] |
| 16. Schultz, David C DC, Ayyanathan, Kasirajan K, Negorev, Dmitri D, Maul, Gerd G GG and Rauscher, Frank J FJ.. (2002) SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.. Genes & development, (15): [PMID:11959841] |
| 17. Andersen, Jens S JS and 5 more authors.. (2003) Proteomic characterization of the human centrosome by protein correlation profiling.. Nature, (4): [PMID:14654843] |
| 18. Lechner, Mark S MS, Schultz, David C DC, Negorev, Dmitri D, Maul, Gerd G GG and Rauscher, Frank J FJ.. (2005) The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.. Biochemical and biophysical research communications, (17): [PMID:15882967] |
| 19. Wang, Chuangui C and 6 more authors.. (2005) MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation.. The EMBO journal, (21): [PMID:16107876] |
| 20. Delfino, Frank J FJ, Shaffer, Jonathan M JM and Smithgall, Thomas E TE.. (2006) The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase.. The Biochemical journal, (1): [PMID:16792528] |
| 21. Beausoleil, Sean A SA, Villén, Judit J, Gerber, Scott A SA, Rush, John J and Gygi, Steven P SP.. (2006) A probability-based approach for high-throughput protein phosphorylation analysis and site localization.. Nature biotechnology, [PMID:16964243] |
| 22. Okamoto, Koji K, Kitabayashi, Issay I and Taya, Yoichi Y.. (2006) KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction.. Biochemical and biophysical research communications, (8): [PMID:17056014] |
| 23. Lee, Yung-Kang YK, Thomas, Stefani N SN, Yang, Austin J AJ and Ann, David K DK.. (2007) Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells.. The Journal of biological chemistry, (19): [PMID:17079232] |
| 24. White, David E DE and 5 more authors.. (2006) KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions.. Cancer research, (15): [PMID:17178852] |
| 25. Peng, Hongzhuang H and 10 more authors.. (2007) The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain.. Journal of molecular biology, (6): [PMID:17512541] |
| 26. Matsuoka, Shuhei S and 12 more authors.. (2007) ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.. Science (New York, N.Y.), (25): [PMID:17525332] |
| 27. Wang, Chuangui C, Rauscher, Frank J FJ, Cress, W Douglas WD and Chen, Jiandong J.. (2007) Regulation of E2F1 function by the nuclear corepressor KAP1.. The Journal of biological chemistry, (12): [PMID:17704056] |
| 28. Yu, Li-Rong LR and 5 more authors.. (2007) Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.. Journal of proteome research, [PMID:17924679] |
| 29. Li, Xu X and 6 more authors.. (2007) Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.. The Journal of biological chemistry, (14): [PMID:17942393] |
| 30. Yang, Bing B and 13 more authors.. (2007) MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines.. Cancer research, (15): [PMID:17942928] |
| 31. Suzuki, Chikage C and 8 more authors.. (2008) A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.. Biochemical and biophysical research communications, (1): [PMID:18060868] |
| 32. Ivanov, Alexey V AV and 12 more authors.. (2007) PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing.. Molecular cell, (14): [PMID:18082607] |
| 33. Okazaki, Noriko N and 7 more authors.. (2008) The novel protein complex with SMARCAD1/KIAA1122 binds to the vicinity of TSS.. Journal of molecular biology, (3): [PMID:18675275] |
| 34. Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18): [PMID:19690332] |
| 35. Crawford, Nigel P S NP, Yang, Hailiu H, Mattaini, Katherine R KR and Hunter, Kent W KW.. (2009) The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor.. The Journal of biological chemistry, (16): [PMID:19710015] |
| 36. Li, Xu X and 5 more authors.. (2010) SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.. Science signaling, (27): [PMID:20424263] |
| 37. Nozawa, Ryu-Suke RS and 7 more authors.. (2010) Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.. Nature cell biology, [PMID:20562864] |
| 38. Gilmore-Hebert, Maureen M, Ramabhadran, Rajani R and Stern, David F DF.. (2010) Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.. Molecular cancer research : MCR, [PMID:20858735] |
| 39. Doyle, Jennifer M JM, Gao, Jinlan J, Wang, Jiawei J, Yang, Maojun M and Potts, Patrick Ryan PR.. (2010) MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases.. Molecular cell, (24): [PMID:20864041] |
| 40. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
| 41. Rowbotham, Samuel P SP and 12 more authors.. (2011) Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.. Molecular cell, (6): [PMID:21549307] |
| 42. Liang, Qiming Q and 9 more authors.. (2011) Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:21940674] |
| 43. Bienvenut, Willy V WV and 6 more authors.. (2012) Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.. Molecular & cellular proteomics : MCP, [PMID:22223895] |
| 44. Van Damme, Petra P and 15 more authors.. (2012) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.. Proceedings of the National Academy of Sciences of the United States of America, (31): [PMID:22814378] |
| 45. Yüce, Özlem Ö and West, Stephen C SC.. (2013) Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.. Molecular and cellular biology, [PMID:23149945] |
| 46. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 47. Huang, Chunjian C and 7 more authors.. (2013) Cutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:23543754] |
| 48. Wang, Wei W and 9 more authors.. (2013) Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.. Cellular and molecular life sciences : CMLS, [PMID:23665872] |
| 49. Serra, Ryan W RW, Fang, Minggang M, Park, Sung Mi SM, Hutchinson, Lloyd L and Green, Michael R MR.. (2014) A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype.. eLife, (12): [PMID:24623306] |
| 50. Kim, Hyungjin H and 6 more authors.. (2014) Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis.. Molecular cell, (10): [PMID:24657165] |
| 51. Gong, Fade F and 11 more authors.. (2015) Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.. Genes & development, (15): [PMID:25593309] |
| 52. Hendriks, Ivo A; Treffers, Louise W; Verlaan-de Vries, Matty; Olsen, Jesper V and Vertegaal, Alfred C O.. (2015) SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage.. Cell reports, (17): [PMID:25772364] |
| 53. Valle-García, David D and 8 more authors.. (2016) ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment.. Epigenetics, (2): [PMID:27029610] |
| 54. Al Chiblak, Mohannad; Steinbeck, Felix; Thiesen, Hans-Jürgen and Lorenz, Peter.. (2019) DUF3669, a "domain of unknown function" within ZNF746 and ZNF777, oligomerizes and contributes to transcriptional repression.. BMC molecular and cell biology, (19): [PMID:31856708] |
| 55. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460] |
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