KB SRC 4 - ≥98%(HPLC), high purity , CAS No.1380088-03-8

  • ≥98%(HPLC)
Item Number
K288228
Grouped product items
SKUSizeAvailabilityPrice Qty
K288228-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$229.90
K288228-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$283.90
K288228-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$829.90
K288228-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,136.90

Potent and selective c-Src inhibitor

View related series
Src Kinase Inhibitors

Basic Description

Synonyms1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsPotent and selective c-Src inhibitor (Ki= 44 nM); does not inhibit c-Abl at concentrations up to 125μM. Selective between Src family members (Kdvalues are 86, 160, 240, 720, 3200, 4400, and >40,000 nM for c-Src, Lck, Fgr, Yes, Lyn, Hck and Fyn respectivel
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

LCK Tclin Tyrosine-protein kinase LCK (9212 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
YES1 Tclin Tyrosine-protein kinase YES (2781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-BR-3 (5175 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMEC (560 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FGR Tchem Tyrosine-protein kinase FGR (1748 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3-(4-chlorophenyl)-1-[3-[3-[(3-phenylphenyl)methyl]triazol-4-yl]phenyl]pyrazolo[3,4-d]pyrimidin-4-amine
INCHI InChI=1S/C32H23ClN8/c33-26-14-12-23(13-15-26)30-29-31(34)35-20-36-32(29)41(38-30)27-11-5-10-25(17-27)28-18-37-39-40(28)19-21-6-4-9-24(16-21)22-7-2-1-3-8-22/h1-18,20H,19H2,(H2,34,35,36)
InChi Key UHIZYQVRKSWIFO-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C2=CC=CC(=C2)CN3C(=CN=N3)C4=CC(=CC=C4)N5C6=NC=NC(=C6C(=N5)C7=CC=C(C=C7)Cl)N
Isomeric SMILES C1=CC=C(C=C1)C2=CC=CC(=C2)CN3C(=CN=N3)C4=CC(=CC=C4)N5C6=NC=NC(=C6C(=N5)C7=CC=C(C=C7)Cl)N
PubChem CID 73349077
Molecular Weight 555.03

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Certificate of Analysis(COA)

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7 results found

Lot NumberCertificate TypeDateItem
G2415353Certificate of AnalysisApr 01, 2024 K288228
G2415354Certificate of AnalysisApr 01, 2024 K288228
G2415355Certificate of AnalysisApr 01, 2024 K288228
G2415356Certificate of AnalysisApr 01, 2024 K288228
G2415357Certificate of AnalysisApr 01, 2024 K288228
G2415358Certificate of AnalysisApr 01, 2024 K288228
G2415359Certificate of AnalysisApr 01, 2024 K288228

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 11.1, Max Conc. mM: 20

Related Documents

Solution Calculators