Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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K288228-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $229.90 | |
K288228-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $283.90 | |
K288228-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $829.90 | |
K288228-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,136.90 |
Potent and selective c-Src inhibitor
Synonyms | 1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Potent and selective c-Src inhibitor (Ki= 44 nM); does not inhibit c-Abl at concentrations up to 125μM. Selective between Src family members (Kdvalues are 86, 160, 240, 720, 3200, 4400, and >40,000 nM for c-Src, Lck, Fgr, Yes, Lyn, Hck and Fyn respectivel |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
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IUPAC Name | 3-(4-chlorophenyl)-1-[3-[3-[(3-phenylphenyl)methyl]triazol-4-yl]phenyl]pyrazolo[3,4-d]pyrimidin-4-amine |
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INCHI | InChI=1S/C32H23ClN8/c33-26-14-12-23(13-15-26)30-29-31(34)35-20-36-32(29)41(38-30)27-11-5-10-25(17-27)28-18-37-39-40(28)19-21-6-4-9-24(16-21)22-7-2-1-3-8-22/h1-18,20H,19H2,(H2,34,35,36) |
InChi Key | UHIZYQVRKSWIFO-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C=C1)C2=CC=CC(=C2)CN3C(=CN=N3)C4=CC(=CC=C4)N5C6=NC=NC(=C6C(=N5)C7=CC=C(C=C7)Cl)N |
Isomeric SMILES | C1=CC=C(C=C1)C2=CC=CC(=C2)CN3C(=CN=N3)C4=CC(=CC=C4)N5C6=NC=NC(=C6C(=N5)C7=CC=C(C=C7)Cl)N |
PubChem CID | 73349077 |
Molecular Weight | 555.03 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2415353 | Certificate of Analysis | Apr 01, 2024 | K288228 |
G2415354 | Certificate of Analysis | Apr 01, 2024 | K288228 |
G2415355 | Certificate of Analysis | Apr 01, 2024 | K288228 |
G2415356 | Certificate of Analysis | Apr 01, 2024 | K288228 |
G2415357 | Certificate of Analysis | Apr 01, 2024 | K288228 |
G2415358 | Certificate of Analysis | Apr 01, 2024 | K288228 |
G2415359 | Certificate of Analysis | Apr 01, 2024 | K288228 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 11.1, Max Conc. mM: 20 |
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