| 1. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O. (1998) Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.. DNA Res, 5 (3): (169-76). [PMID:9734811] |
| 2. Shen Y, Szewczyk MM, Eram MS, Smil D, Kaniskan HÜ, Ferreira de Freitas R, Senisterra G, Li F, Schapira M, Brown PJ et al.. (2016) Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.. J Med Chem, 59 (19): (9124-9139). [PMID:27584694] |
| 3. Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M et al.. (2006) Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.. Cell, 125 (3): (467-81). [PMID:16603238] |
| 4. Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai G, Mott BT, Jansen DJ, Kales SC et al.. (2018) Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.. J Med Chem, 61 (23): (10588-10601). [PMID:30392349] |
| 5. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330] |
| 6. Rose NR, Woon EC, Kingham GL, King ON, Mecinović J, Clifton IJ, Ng SS, Talib-Hardy J, Oppermann U, McDonough MA, Schofield CJ.. (2010) Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.. J Med Chem, 53 (4): (1810-1818). [PMID:20088513] |
| 7. Lopes da Rosa J, Bajaj V, Spoonamore J, Kaufman PD.. (2013) A small molecule inhibitor of fungal histone acetyltransferase Rtt109.. Bioorg Med Chem Lett, 23 (10): (2853-2859). [PMID:23587423] |
| 8. Xu W, Podoll JD, Dong X, Tumber A, Oppermann U, Wang X.. (2013) Quantitative analysis of histone demethylase probes using fluorescence polarization.. J Med Chem, 56 (12): (5198-5202). [PMID:23725560] |
| 9. Chu CH, Wang LY, Hsu KC, Chen CC, Cheng HH, Wang SM, Wu CM, Chen TJ, Li LT, Liu R, Hung CL, Yang JM, Kung HJ, Wang WC.. (2014) KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor.. J Med Chem, 57 (14): (5975-5985). [PMID:24971742] |
| 10. England KS, Tumber A, Krojer T, Scozzafava G, Ng SS, Daniel M, Szykowska A, Che K, von Delft F, Burgess-Brown NA, Kawamura A, Schofield CJ, Brennan PE.. (2014) Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.. Medchemcomm, 5 (12): (1879-1886). [PMID:26682034] |
| 11. Bavetsias V, Lanigan RM, Ruda GF, Atrash B, McLaughlin MG, Tumber A, Mok NY, Le Bihan YV, Dempster S, Boxall KJ, Jeganathan F, Hatch SB, Savitsky P, Velupillai S, Krojer T, England KS, Sejberg J, Thai C, Donovan A, Pal A, Scozzafava G, Bennett JM, Kawamura A, Johansson C, Szykowska A, Gileadi C, Burgess-Brown NA, von Delft F, Oppermann U, Walters Z, Shipley J, Raynaud FI, Westaway SM, Prinjha RK, Fedorov O, Burke R, Schofield CJ, Westwood IM, Bountra C, Müller S, van Montfort RL, Brennan PE, Blagg J.. (2016) 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors.. J Med Chem, 59 (4): (1388-1409). [PMID:26741168] |
| 12. Westaway SM, Preston AG, Barker MD, Brown F, Brown JA, Campbell M, Chung CW, Diallo H, Douault C, Drewes G, Eagle R, Gordon L, Haslam C, Hayhow TG, Humphreys PG, Joberty G, Katso R, Kruidenier L, Leveridge M, Liddle J, Mosley J, Muelbaier M, Randle R, Rioja I, Rueger A, Seal GA, Sheppard RJ, Singh O, Taylor J, Thomas P, Thomson D, Wilson DM, Lee K, Prinjha RK.. (2016) Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.. J Med Chem, 59 (4): (1357-1369). [PMID:26771107] |
| 13. Le Bihan YV, Lanigan RM, Atrash B, McLaughlin MG, Velupillai S, Malcolm AG, England KS, Ruda GF, Mok NY, Tumber A, Tomlin K, Saville H, Shehu E, McAndrew C, Carmichael L, Bennett JM, Jeganathan F, Eve P, Donovan A, Hayes A, Wood F, Raynaud FI, Fedorov O, Brennan PE, Burke R, van Montfort RLM, Rossanese OW, Blagg J, Bavetsias V.. (2019) C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays.. Eur J Med Chem, 177 (316-337). [PMID:31158747] |
| 14. Jaikhan P, Buranrat B, Itoh Y, Chotitumnavee J, Kurohara T, Suzuki T.. (2019) Identification of ortho-hydroxy anilide as a novel scaffold for lysine demethylase 5 inhibitors.. Bioorg Med Chem Lett, 29 (10): (1173-1176). [PMID:30928196] |
| 15. Holt-Martyn JP, Tumber A, Rahman MZ, Lippl K, Figg W, Figg W, McDonough MA, Chowdhury R, Schofield CJ.. (2019) Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors.. Medchemcomm, 10 (4): (500-504). [PMID:31057728] |
| 16. Letfus V, Jelić D, Bokulić A, Petrinić Grba A, Koštrun S.. (2020) Rational design, synthesis and biological profiling of new KDM4C inhibitors.. Bioorg Med Chem, 28 (1): (115128-115128). [PMID:31784197] |
| 17. Zhao B,Liang Q,Ren H,Zhang X,Wu Y,Zhang K,Ma LY,Zheng YC,Liu HM. (2020) Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B).. Eur J Med Chem, 192 (112161-112161). [PMID:32155529] |
| 18. Gray, Steven G SG and 10 more authors.. (2005) Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein.. The Journal of biological chemistry, (5): [PMID:15927959] |
| 19. Zhang, Dianzheng D, Yoon, Ho-Guen HG and Wong, Jiemin J.. (2005) JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2).. Molecular and cellular biology, [PMID:16024779] |
| 20. Kim, Jeesun J and 7 more authors.. (2006) Tudor, MBT and chromo domains gauge the degree of lysine methylation.. EMBO reports, [PMID:16415788] |
| 21. Huang, Ying Y, Fang, Jia J, Bedford, Mark T MT, Zhang, Yi Y and Xu, Rui-Ming RM.. (2006) Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A.. Science (New York, N.Y.), (5): [PMID:16601153] |
| 22. Chen, Zhongzhou Z and 13 more authors.. (2006) Structural insights into histone demethylation by JMJD2 family members.. Cell, (19): [PMID:16677698] |
| 23. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |
| 24. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
| 25. Verrier, Laure; Escaffit, Fabrice; Chailleux, Catherine; Trouche, Didier and Vandromme, Marie.. (2011) A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation.. PLoS genetics, [PMID:21694756] |
| 26. Mallette, Frédérick A FA and 7 more authors.. (2012) RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.. The EMBO journal, (18): [PMID:22373579] |
| 27. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 28. Johansson, Catrine C and 23 more authors.. (2016) Structural analysis of human KDM5B guides histone demethylase inhibitor development.. Nature chemical biology, [PMID:27214403] |
| 29. Tumber, Anthony A and 27 more authors.. (2017) Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.. Cell chemical biology, (16): [PMID:28262558] |
