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KDOAM25 , CAS No.K611325

Item Number
K611325
Grouped product items
SKUSizeAvailabilityPrice Qty
K611325-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
K611325-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,001.90
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Basic Description

SynonymsKDOAM-25
Specifications & PurityMoligand™
GradeMoligand™

Associated Targets(Human)

KDM5B Tchem Lysine-specific demethylase 5B (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM4C Tchem Lysine-specific demethylase 4C (1129 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM5C Tchem Lysine-specific demethylase 5C (224 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM5A Tchem Lysine-specific demethylase 5A (893 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM5B Tchem Lysine-specific demethylase 5B (814 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MM1.S (1111 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM5D Tbio Lysine-specific demethylase 5D (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-[[[2-[2-(dimethylamino)ethyl-ethylamino]-2-oxoethyl]amino]methyl]pyridine-4-carboxamide
INCHI InChI=1S/C15H25N5O2/c1-4-20(8-7-19(2)3)14(21)11-17-10-13-9-12(15(16)22)5-6-18-13/h5-6,9,17H,4,7-8,10-11H2,1-3H3,(H2,16,22)
InChi Key PNFMVADNCOGWME-UHFFFAOYSA-N
Canonical SMILES CCN(C(=O)CNCc1nccc(c1)C(=O)N)CCN(C)C
Isomeric SMILES CCN(CCN(C)C)C(=O)CNCC1=NC=CC(=C1)C(=O)N
PubChem CID 91810435

Certificates

Certificate of Analysis(COA)

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Related Documents

 SDS

 Specification Sheet

References

1. Adegbola A, Gao H, Sommer S, Browning M.  (2008)  A novel mutation in JARID1C/SMCX in a patient with autism spectrum disorder (ASD)..  Am J Med Genet A,  146A  (4): (505-11).  [PMID:18203167]
2. Blair LP, Cao J, Zou MR, Sayegh J, Yan Q.  (2011)  Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer..  Cancers (Basel),  3  (1): (1383-404).  [PMID:21544224]
3. Teng YC, Lee CF, Li YS, Chen YR, Hsiao PW, Chan MY, Lin FM, Huang HD, Chen YT, Jeng YM et al..  (2013)  Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis..  Cancer Res,  73  (15): (4711-21).  [PMID:23722541]
4. Gonçalves TF, Gonçalves AP, Fintelman Rodrigues N, dos Santos JM, Pimentel MM, Santos-Rebouças CB.  (2014)  KDM5C mutational screening among males with intellectual disability suggestive of X-Linked inheritance and review of the literature..  Eur J Med Genet,  57  (4): (138-44).  [PMID:24583395]

Solution Calculators

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