Ketoprofen - ≥98%(HPLC), high purity , Cyclooxygenase inhibitor, CAS No.22071-15-4, Cyclooxygenase inhibitor

Item Number
K129331
Grouped product items
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K129331-5g
5g
In stock
$103.90
K129331-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$187.90
K129331-25g
25g
In stock
$421.90
K129331-100g
100g
In stock
$1,516.90
K129331-250g
250g
In stock
$3,411.90
K129331-500g
500g
In stock
$6,141.90

Non-selective COX inhibitor

Basic Description

SynonymsDTXSID6020771 | Iso-K | Ketoprofenum [INN-Latin] | Acide (benzoyl-3-phenyl)-2-propionique | KetoMed | KETOPROFEN [JAN] | L'Acide (benzoyl-3-phenyl)-2-propionique | R.P. 19583 | NSC 758144 | Toprek | Alrheumat | Propionic acid, 2-(3-benzoylphenyl)- | rac K
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsKetoprofen is a non-selective NSAID which inhibits both human recombinant Cox-1 (IC50 of 0.5 μM) and Cox-2 (IC50 of 2.33 μM). Ketoprofen is used for its antipyretic, analgesic, and anti-inflammatory properties by inhibiting Cox-1 and Cox-2 (cyclooxygenase
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionCyclooxygenase inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Ketoprofen is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.
An inhibitor of Cox-1 and Cox-2.

Product Properties

ALogP3.1

Associated Targets(Human)

SLC5A8 Tchem Sodium-coupled monocarboxylate transporter 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Prostaglandin G/H synthase 2 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glo1 Glyoxalase I (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGES Prostaglandin E synthase (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pneumocystis carinii (749 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania infantum (5912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei (78846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptosporidium parvum (1150 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania amazonensis (3813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania mexicana (936 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Toxoplasma gondii (4585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 2 (4932 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human respirovirus 3 (1674 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vaccinia virus (4609 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 1 (11089 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sindbis virus (1599 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vesicular stomatitis virus (4460 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Influenza A virus (11224 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Punta Toro virus (1491 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Coxsackievirus B4 (2249 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Respiratory syncytial virus (3434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei rhodesiense (7991 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDCK (10148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LOX1.1 Seed lipoxygenase-1 (463 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488179798
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179798
IUPAC Name 2-(3-benzoylphenyl)propanoic acid
INCHI InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
InChi Key DKYWVDODHFEZIM-UHFFFAOYSA-N
Canonical SMILES CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O
Isomeric SMILES CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O
WGK Germany 3
RTECS UE7570000
PubChem CID 3825
Molecular Weight 254.28
Reaxy-Rn 2216071

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

19 results found

Lot NumberCertificate TypeDateItem
B2317899Certificate of AnalysisDec 05, 2024 K129331
B2317927Certificate of AnalysisDec 05, 2024 K129331
B2318172Certificate of AnalysisDec 05, 2024 K129331
B2317898Certificate of AnalysisDec 05, 2024 K129331
F23131113Certificate of AnalysisMay 29, 2023 K129331
F23131231Certificate of AnalysisMay 29, 2023 K129331
F23131230Certificate of AnalysisMay 29, 2023 K129331
F23131229Certificate of AnalysisMay 29, 2023 K129331
F23131119Certificate of AnalysisMay 29, 2023 K129331
F23131118Certificate of AnalysisMay 29, 2023 K129331
F23131071Certificate of AnalysisMay 29, 2023 K129331
F23131070Certificate of AnalysisMay 29, 2023 K129331
G2123241Certificate of AnalysisMay 10, 2023 K129331
B2317903Certificate of AnalysisDec 20, 2022 K129331
B2317902Certificate of AnalysisDec 20, 2022 K129331
B2317901Certificate of AnalysisDec 20, 2022 K129331
K2210239Certificate of AnalysisNov 11, 2022 K129331
L2009182Certificate of AnalysisOct 17, 2022 K129331
K1826111Certificate of AnalysisJul 13, 2022 K129331

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Chemical and Physical Properties

SolubilitySoluble in ethanol (51 mg/ml at 25 °C), DMSO (51 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), DMF (≥20 mg/ml), and PBS (pH 7.2) (≥0.5 mg/ml).
SensitivityLight sensitive
Melt Point(°C)92-97°

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H301:Toxic if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS UE7570000
Reaxy-Rn 2216071
Merck Index 5305

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5. Hao-Ze Li, Cheng Yang, Hai-Long Qian, Xiu-Ping Yan.  (2023)  Room-temperature synthesis of ionic covalent organic frameworks for efficient removal of diclofenac sodium from aqueous solution.  SEPARATION AND PURIFICATION TECHNOLOGY,  306  (122704).  [PMID:] [10.1016/j.seppur.2022.122704]
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8. Lixiao Wang, Yajie Zheng, Yiran Zhou, Junhe Lu, Jean-Marc Chovelon, Yuefei Ji.  (2022)  Aquatic photolysis of ketoprofen generates products with photosensitizing activity and toxicity.  WATER RESEARCH,  210  (117982).  [PMID:34954366] [10.1016/j.watres.2021.117982]
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14. Qian Han, Cun Wang, Pingkun Liu, Gui Zhang, Li Song, Yingzi Fu.  (2021)  Achieving synergistically enhanced dual-mode electrochemiluminescent and electrochemical drug sensors via a multi-effect porphyrin-based metal-organic framework.  SENSORS AND ACTUATORS B-CHEMICAL,  330  (129388).  [PMID:] [10.1016/j.snb.2020.129388]
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16. Tiemei Li, Yuefei Song, Zhaoqi Dong, Yueyue Shi, Jing Fan.  (2020)  Hydrophobic deep eutectic solvents as extractants for the determination of bisphenols from food-contacted plastics by high performance liquid chromatography with fluorescence detection.  JOURNAL OF CHROMATOGRAPHY A,  1621  (461087).  [PMID:32327226] [10.1016/j.chroma.2020.461087]
17. Guanqiong Na, Xiaofei Hu, Yaning Sun, Guangxu Xing, Yunrui Xing, Gaiping Zhang.  (2020)  A novel gold particle-based paper sensor for sensitively detecting carprofen in bovine muscle.  FOOD AND AGRICULTURAL IMMUNOLOGY,  31  (1): (463-474).  [PMID:] [10.1080/09540105.2020.1740178]
18. Yixian Zhou, Sulan Luo, Boyi Niu, Biyuan Wu, Jintao Fu, Yiting Zhao, Vikramjeet Singh, Chao Lu, Guilan Quan, Xin Pan, Jiwen Zhang, Chuanbin Wu.  (2019)  Ultramild One-Step Encapsulating Method as a Modular Strategy for Protecting Humidity-Susceptible Metal–Organic Frameworks Achieving Tunable Drug Release Profiles.  ACS Biomaterials Science & Engineering,  (10): (5180–5188).  [PMID:33455224] [10.1021/acsbiomaterials.9b01233]
19. Tong Wang, Hai-Long Wu, Yong-Jie Yu, Wan-Jun Long, Li Cheng, An-Qi Chen, Ru-Qin Yu.  (2019)  A simple method for direct modeling of second-order liquid chromatographic data with retention time shifts and holding the second-order advantage.  JOURNAL OF CHROMATOGRAPHY A,  1605  (360360).  [PMID:31326090] [10.1016/j.chroma.2019.07.014]
20. Nadeem Muhammad, Dandan Guo, Yun Zhang, Azeem Intisar, Qamar Subhani, Muhammad Abdul Qadir, Hairong Cui.  (2019)  Online clean-up setup for the determination of non-fluorescent acidic pharmaceutical drugs in complex biological samples.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  1126-1127  (121708).  [PMID:31437773] [10.1016/j.jchromb.2019.06.035]
21. Wang Xiaobing, Zhu Huijuan, Shi Xiuyi, Qiu Xiuzhen, Lu Wenguan, Guo Huishi.  (2019)  Synthesis of MOF-199/CNTs Nanocomposite for Selective Adsorption and Determination of Nonsteroidal Anti-Inflammatory Drugs in Human Urine.  JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,  19  (2): (627-633).  [PMID:30360133] [10.1166/jnn.2019.15733]
22. Na Li, Juan Chen, Yan-Ping Shi.  (2019)  Magnetic polyethyleneimine functionalized reduced graphene oxide as a novel magnetic sorbent for the separation of polar non-steroidal anti-inflammatory drugs in waters.  TALANTA,  191  (526).  [PMID:30262094] [10.1016/j.talanta.2018.09.006]
23. Yue Zhai, Xue Bai, Jinyang Zhu, Xueke Sun, Gencai Pan, Biao Dong, Lin Xu, Wen Xu, Shuang Zhang, Hongwei Song.  (2018)  Luminescence carbon dot-based nanofibers for a water-insoluble drug release system and their monitoring of drug release.  Journal of Materials Chemistry B,  (21): (3579-3585).  [PMID:32254453] [10.1039/C8TB00117K]
24. Xuemei Wang, Wei Zhou, Chenlu Wang, Zilin Chen.  (2018)  Cotton fiber-supported layered double hydroxides for the highly efficient adsorption of anionic organic pollutants in water.  NEW JOURNAL OF CHEMISTRY,  42  (12): (9463-9471).  [PMID:] [10.1039/C8NJ00678D]
25. Wang Tong, Wu Hai-Long, Xie Li-Xia, Liu Zhi, Long Wan-Jun, Cheng Li, Ding Yu-Jie, Yu Ru-Qin.  (2018)  Simultaneous and interference-free determination of eleven non-steroidal anti-inflammatory drugs illegally added into Chinese patent drugs using chemometrics-assisted HPLC-DAD strategy.  Science China-Chemistry,  61  (6): (739-749).  [PMID:] [10.1007/s11426-017-9210-8]
26. Xue Shu-Wen, Li Jing, Xu Li.  (2017)  Preparation of magnetic melamine-formaldehyde resin and its application to extract nonsteroidal anti-inflammatory drugs.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  409  (12): (3103-3113).  [PMID:28224244] [10.1007/s00216-017-0251-8]
27. Ning Zhuo, Yaqian Lan, Weiben Yang, Zhen Yang, Xiaomin Li, Xia Zhou, Yang Liu, Jiachun Shen, Xuntong Zhang.  (2017)  Adsorption of three selected pharmaceuticals and personal care products (PPCPs) onto MIL-101(Cr)/natural polymer composite beads.  SEPARATION AND PURIFICATION TECHNOLOGY,  177  (272).  [PMID:] [10.1016/j.seppur.2016.12.041]
28. Luo Zhi-yuan, Li Zhi-yong, Liu Hai-yan, Tang Min-qiong, Shi Zhi-guo.  (2015)  Click chemistry-based synthesis of water-dispersible hydrophobic magnetic nanoparticles for use in solid phase extraction of non-steroidal anti-inflammatory drugs.  MICROCHIMICA ACTA,  182  (15): (2585-2591).  [PMID:] [10.1007/s00604-015-1638-x]

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17. Guanqiong Na, Xiaofei Hu, Yaning Sun, Guangxu Xing, Yunrui Xing, Gaiping Zhang.  (2020)  A novel gold particle-based paper sensor for sensitively detecting carprofen in bovine muscle.  FOOD AND AGRICULTURAL IMMUNOLOGY,  31  (1): (463-474).  [PMID:] [10.1080/09540105.2020.1740178]
18. Yixian Zhou, Sulan Luo, Boyi Niu, Biyuan Wu, Jintao Fu, Yiting Zhao, Vikramjeet Singh, Chao Lu, Guilan Quan, Xin Pan, Jiwen Zhang, Chuanbin Wu.  (2019)  Ultramild One-Step Encapsulating Method as a Modular Strategy for Protecting Humidity-Susceptible Metal–Organic Frameworks Achieving Tunable Drug Release Profiles.  ACS Biomaterials Science & Engineering,  (10): (5180–5188).  [PMID:33455224] [10.1021/acsbiomaterials.9b01233]
19. Tong Wang, Hai-Long Wu, Yong-Jie Yu, Wan-Jun Long, Li Cheng, An-Qi Chen, Ru-Qin Yu.  (2019)  A simple method for direct modeling of second-order liquid chromatographic data with retention time shifts and holding the second-order advantage.  JOURNAL OF CHROMATOGRAPHY A,  1605  (360360).  [PMID:31326090] [10.1016/j.chroma.2019.07.014]
20. Nadeem Muhammad, Dandan Guo, Yun Zhang, Azeem Intisar, Qamar Subhani, Muhammad Abdul Qadir, Hairong Cui.  (2019)  Online clean-up setup for the determination of non-fluorescent acidic pharmaceutical drugs in complex biological samples.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  1126-1127  (121708).  [PMID:31437773] [10.1016/j.jchromb.2019.06.035]
21. Wang Xiaobing, Zhu Huijuan, Shi Xiuyi, Qiu Xiuzhen, Lu Wenguan, Guo Huishi.  (2019)  Synthesis of MOF-199/CNTs Nanocomposite for Selective Adsorption and Determination of Nonsteroidal Anti-Inflammatory Drugs in Human Urine.  JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,  19  (2): (627-633).  [PMID:30360133] [10.1166/jnn.2019.15733]
22. Na Li, Juan Chen, Yan-Ping Shi.  (2019)  Magnetic polyethyleneimine functionalized reduced graphene oxide as a novel magnetic sorbent for the separation of polar non-steroidal anti-inflammatory drugs in waters.  TALANTA,  191  (526).  [PMID:30262094] [10.1016/j.talanta.2018.09.006]
23. Yue Zhai, Xue Bai, Jinyang Zhu, Xueke Sun, Gencai Pan, Biao Dong, Lin Xu, Wen Xu, Shuang Zhang, Hongwei Song.  (2018)  Luminescence carbon dot-based nanofibers for a water-insoluble drug release system and their monitoring of drug release.  Journal of Materials Chemistry B,  (21): (3579-3585).  [PMID:32254453] [10.1039/C8TB00117K]
24. Xuemei Wang, Wei Zhou, Chenlu Wang, Zilin Chen.  (2018)  Cotton fiber-supported layered double hydroxides for the highly efficient adsorption of anionic organic pollutants in water.  NEW JOURNAL OF CHEMISTRY,  42  (12): (9463-9471).  [PMID:] [10.1039/C8NJ00678D]
25. Wang Tong, Wu Hai-Long, Xie Li-Xia, Liu Zhi, Long Wan-Jun, Cheng Li, Ding Yu-Jie, Yu Ru-Qin.  (2018)  Simultaneous and interference-free determination of eleven non-steroidal anti-inflammatory drugs illegally added into Chinese patent drugs using chemometrics-assisted HPLC-DAD strategy.  Science China-Chemistry,  61  (6): (739-749).  [PMID:] [10.1007/s11426-017-9210-8]
26. Xue Shu-Wen, Li Jing, Xu Li.  (2017)  Preparation of magnetic melamine-formaldehyde resin and its application to extract nonsteroidal anti-inflammatory drugs.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  409  (12): (3103-3113).  [PMID:28224244] [10.1007/s00216-017-0251-8]
27. Ning Zhuo, Yaqian Lan, Weiben Yang, Zhen Yang, Xiaomin Li, Xia Zhou, Yang Liu, Jiachun Shen, Xuntong Zhang.  (2017)  Adsorption of three selected pharmaceuticals and personal care products (PPCPs) onto MIL-101(Cr)/natural polymer composite beads.  SEPARATION AND PURIFICATION TECHNOLOGY,  177  (272).  [PMID:] [10.1016/j.seppur.2016.12.041]
28. Luo Zhi-yuan, Li Zhi-yong, Liu Hai-yan, Tang Min-qiong, Shi Zhi-guo.  (2015)  Click chemistry-based synthesis of water-dispersible hydrophobic magnetic nanoparticles for use in solid phase extraction of non-steroidal anti-inflammatory drugs.  MICROCHIMICA ACTA,  182  (15): (2585-2591).  [PMID:] [10.1007/s00604-015-1638-x]

Solution Calculators