Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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K129331-5g | 5g | In stock | $103.90 | |
K129331-10g | 10g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $187.90 | |
K129331-25g | 25g | In stock | $421.90 | |
K129331-100g | 100g | In stock | $1,516.90 | |
K129331-250g | 250g | In stock | $3,411.90 | |
K129331-500g | 500g | In stock | $6,141.90 |
Non-selective COX inhibitor
Synonyms | ketoprofen|22071-15-4|2-(3-Benzoylphenyl)propanoic acid|2-(3-Benzoylphenyl)propionic acid|Orudis|Actron|Capisten|Oruvail|m-Benzoylhydratropic acid|Ketoprofene|Aneol|3-Benzoylhydratropic acid|Alrheumat|Alrheumun|Profenid|Epatec|Iso-K|Orudis KT|Ketoprophene |
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Specifications & Purity | Moligand™, ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Ketoprofen is a non-selective NSAID which inhibits both human recombinant Cox-1 (IC50 of 0.5 μM) and Cox-2 (IC50 of 2.33 μM). Ketoprofen is used for its antipyretic, analgesic, and anti-inflammatory properties by inhibiting Cox-1 and Cox-2 (cyclooxygenase |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Cyclooxygenase inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Ketoprofen is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively. |
ALogP | 3.1 |
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Pubchem Sid | 488179798 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179798 |
IUPAC Name | 2-(3-benzoylphenyl)propanoic acid |
INCHI | InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) |
InChi Key | DKYWVDODHFEZIM-UHFFFAOYSA-N |
Canonical SMILES | CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O |
Isomeric SMILES | CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O |
WGK Germany | 3 |
RTECS | UE7570000 |
PubChem CID | 3825 |
Molecular Weight | 254.28 |
Reaxy-Rn | 2216071 |
DrugBank Ligand | DB01009 |
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Wikipedia | Ketoprofen |
ChEBI | CHEBI:6128 |
CAS Registry No. | 22071-15-4 |
ChEMBL Ligand | CHEMBL571 |
PubChem CID | 3825 |
PEP | ketoprofen |
DrugCentral Ligand | 1528 |
PubChem SID | 488179798 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F23131231 | Certificate of Analysis | May 29, 2023 | K129331 |
F23131230 | Certificate of Analysis | May 29, 2023 | K129331 |
F23131229 | Certificate of Analysis | May 29, 2023 | K129331 |
F23131119 | Certificate of Analysis | May 29, 2023 | K129331 |
F23131118 | Certificate of Analysis | May 29, 2023 | K129331 |
F23131070 | Certificate of Analysis | May 29, 2023 | K129331 |
F23131071 | Certificate of Analysis | May 29, 2023 | K129331 |
F23131113 | Certificate of Analysis | May 29, 2023 | K129331 |
G2123241 | Certificate of Analysis | May 10, 2023 | K129331 |
B2317899 | Certificate of Analysis | Dec 20, 2022 | K129331 |
B2318172 | Certificate of Analysis | Dec 20, 2022 | K129331 |
B2317927 | Certificate of Analysis | Dec 20, 2022 | K129331 |
B2317903 | Certificate of Analysis | Dec 20, 2022 | K129331 |
B2317902 | Certificate of Analysis | Dec 20, 2022 | K129331 |
B2317901 | Certificate of Analysis | Dec 20, 2022 | K129331 |
B2317898 | Certificate of Analysis | Dec 20, 2022 | K129331 |
K2210239 | Certificate of Analysis | Nov 11, 2022 | K129331 |
L2009182 | Certificate of Analysis | Oct 17, 2022 | K129331 |
K1826111 | Certificate of Analysis | Jul 13, 2022 | K129331 |
Solubility | Soluble in ethanol (51 mg/ml at 25 °C), DMSO (51 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), DMF (≥20 mg/ml), and PBS (pH 7.2) (≥0.5 mg/ml). |
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Sensitivity | Light sensitive |
Melt Point(°C) | 92-97° |
Pictogram(s) | GHS06, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | UE7570000 |
Reaxy-Rn | 2216071 |
Merck Index | 5305 |