Ki67 Mouse mAb

    Application:
  • IHC
Features and benefits
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG
  • Clone Number: YN00996m
  • Conjugation: Unconjugated
Item Number
Ab112020
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab112020-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab112020-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab112020-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab112020-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,799.90

mAb (YN00996m); Mouse anti Human Ki67 Antibody; IHC; Unconjugated

Basic Description

Product NameKi67 Mouse mAb
SynonymsAntigen identified by monoclonal antibody Ki 67 antibody | Antigen identified by monoclonal antibody Ki-67 antibody | Antigen KI-67 antibody | Antigen KI67 antibody | KI67_HUMAN antibody | KIA antibody | Marker of proliferation Ki-67 antibody | MIB 1 anti
Specifications & PurityCarrier Free, ExactAb™, Azide Free, Validated, 1.0 mg/mL
Host speciesMouse
SpecificityKi67
ImmunogenPeptide
Positive ControlIHC: Human tonsil tissue.
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human Ki67 Antibody, Monoclonal (YN00996m), could be used for IHC and so on.
Application
IHC: 1/200
Protein Function
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed.

Product Properties

IsotypeMouse IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein G purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Ki67 Mouse mAb (Ab112020) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Ki67 with Ki67 Mouse mAb (Ab112020) at 1/400 dilution. The section was incubated with Ki67 Mouse mAb (Ab112020) ​for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Associated Targets(Human)

MKI67 Tbio Proliferation marker protein Ki-67 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

1/200

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0707880Certificate of AnalysisJul 05, 2024 Ab112020
ZJ24F0707879Certificate of AnalysisJul 05, 2024 Ab112020

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