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KT-109 , CAS No.1402612-55-8, Inhibitor of αβ-Hydrolase 6;Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β

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KT-109 , CAS No.1402612-55-8, Inhibitor of αβ-Hydrolase 6;Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β

Moligand™

CAS#: 1402612-55-8
Formula: C₂₇H₂₆N₄O
Molecular Weight: 422.52
PubChem CID: 53364540

Item Number

K611360

Grouped product items
SKU	Size	Availability	Price	Qty
K611360-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
K611360-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

View related series

Diacylglycerol lipase α Inhibitor Diacylglycerol lipase β Inhibitor αβ-Hydrolase 6 Inhibitor

Basic Description

Synonyms	KT109
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of αβ-Hydrolase 6;Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β

Associated Targets

DAGLB Tchem Sn1-specific diacylglycerol lipase beta 2 Activities

Discover Target: DAGLB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DAGLA Tchem Sn1-specific diacylglycerol lipase alpha 4 Activities

Discover Target: DAGLA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABHD6 Tchem Monoacylglycerol lipase ABHD6 2 Activities

Discover Target: ABHD6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2-benzylpiperidin-1-yl)-[4-(4-phenylphenyl)triazol-1-yl]methanone
INCHI	InChI=1S/C27H26N4O/c32-27(30-18-8-7-13-25(30)19-21-9-3-1-4-10-21)31-20-26(28-29-31)24-16-14-23(15-17-24)22-11-5-2-6-12-22/h1-6,9-12,14-17,20,25H,7-8,13,18-19H2
InChi Key	JKJMWHULJIOKPJ-UHFFFAOYSA-N
Canonical SMILES	C1CCN(C(C1)CC2=CC=CC=C2)C(=O)N3C=C(N=N3)C4=CC=C(C=C4)C5=CC=CC=C5
Isomeric SMILES	C1CCN(C(C1)CC2=CC=CC=C2)C(=O)N3C=C(N=N3)C4=CC=C(C=C4)C5=CC=CC=C5
PubChem CID	53364540
Molecular Weight	422.52

Database links

PubChem CID	53364540
ChEMBL Ligand	CHEMBL2144065
CAS Registry No.	1402612-55-8
BindingDB Ligand	50211236

Certificates

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References

1. Hsu KL, Tsuboi K, Adibekian A, Pugh H, Masuda K, Cravatt BF. (2012) DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses.. Nat Chem Biol, 8 (12): (999-1007). [PMID:23103940]

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