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KT182 - ≥99.0%, high purity , CAS No.1402612-62-7
Basic Description
| Synonyms | KT182|1402612-62-7|(4-(3'-(hydroxymethyl)-[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-phenylpiperidin-1-yl)methanone|CHEMBL3263577|[4-[4-[3-(hydroxymethyl)phenyl]phenyl]triazol-1-yl]-(2-phenylpiperidin-1-yl)methanone|[4-[3'-(hydroxymethyl)[1,1'-bipheny |
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| Specifications & Purity | ≥99% |
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| Biochemical and Physiological Mechanisms | KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6) , with an IC 50 of 0.24 nM in Neuro2A cells. |
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| Storage Temp | Store at -20°C |
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| Shipped In | Ice chest + Ice pads |
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| Product Description | KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6) , with an IC 50 of 0.24 nM in Neuro2A cells Form:Solid IC50& Target:IC50: 0.24 nM (ABHD6 in Neuro2A cells) |
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Names and Identifiers
| IUPAC Name | [4-[4-[3-(hydroxymethyl)phenyl]phenyl]triazol-1-yl]-(2-phenylpiperidin-1-yl)methanone |
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| INCHI | InChI=1S/C27H26N4O2/c32-19-20-7-6-10-24(17-20)21-12-14-22(15-13-21)25-18-31(29-28-25)27(33)30-16-5-4-11-26(30)23-8-2-1-3-9-23/h1-3,6-10,12-15,17-18,26,32H,4-5,11,16,19H2 |
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| InChi Key | GICNKPZHUCVFNM-UHFFFAOYSA-N |
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| Canonical SMILES | C1CCN(C(C1)C2=CC=CC=C2)C(=O)N3C=C(N=N3)C4=CC=C(C=C4)C5=CC=CC(=C5)CO |
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| Isomeric SMILES | C1CCN(C(C1)C2=CC=CC=C2)C(=O)N3C=C(N=N3)C4=CC=C(C=C4)C5=CC=CC(=C5)CO |
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| PubChem CID | 53364491 |
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| Molecular Weight | 438.52 |
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Chemical and Physical Properties
| Solubility | DMSO : 100 mg/mL (228.04 mM; Need ultrasonic) Ethanol : 11 mg/mL (25.08 mM; Need ultrasonic and warming) |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
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| Hazard Statements | H413:May cause long lasting harmful effects to aquatic life H302:Harmful if swallowed |
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| Precautionary Statements | P273:Avoid release to the environment. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
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| RIDADR | NONHforallmodesoftransport |
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