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Kuwanon E - ≥96.0%, high purity , CAS No.68401-05-8

  • ≥96%
Item Number
K650940
Grouped product items
SKUSizeAvailabilityPrice Qty
K650940-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$286.90
K650940-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$857.90

Flavonoids Flavonones Phenols Polyphenols

Basic Description

SynonymsKuwanon E|68401-05-8|CHEMBL4173326|4H-1-Benzopyran-4-one, 2-(5-((2E)-3,7-dimethyl-2,6-octadienyl)-2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2S)-|(2S)-2-[5-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-o
Specifications & Purity≥96%
Biochemical and Physiological MechanismsKuwanon E is a flavonoid isolated from Morus alba , cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

Kuwanon E is a flavonoid isolated from Morus alba , cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β

Form:Solid

IC50& Target:Kuwanon E shows cytotoxic activity against THP-1 human monocytic leukemic cell line, with an IC 50 of 4.0±0.08 μM

Associated Targets

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATP2A1 Tchem Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S)-2-[5-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one
INCHI InChI=1S/C25H28O6/c1-14(2)5-4-6-15(3)7-8-16-9-18(20(28)12-19(16)27)23-13-22(30)25-21(29)10-17(26)11-24(25)31-23/h5,7,9-12,23,26-29H,4,6,8,13H2,1-3H3/b15-7+/t23-/m0/s1
InChi Key GJFHZVPRFLHEBR-KETROQBRSA-N
Canonical SMILES CC(=CCCC(=CCC1=CC(=C(C=C1O)O)C2CC(=O)C3=C(C=C(C=C3O2)O)O)C)C
Isomeric SMILES CC(=CCC/C(=C/CC1=CC(=C(C=C1O)O)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)/C)C
Alternate CAS 68401-05-8
PubChem CID 6440408
Molecular Weight 424.5

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