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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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K650940-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $286.90 | |
K650940-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $857.90 |
Flavonoids Flavonones Phenols Polyphenols
Synonyms | (S)-2-[5-[(E)-3,7-Dimethyl-2,6-octadienyl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one | HY-N3514 | (2S)-2-[5-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one | BDBM50291290 | (2S)-2-[ |
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Specifications & Purity | ≥96% |
Biochemical and Physiological Mechanisms | Kuwanon E is a flavonoid isolated from Morus alba , cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β. |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Kuwanon E is a flavonoid isolated from Morus alba , cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β Form:Solid IC50& Target:Kuwanon E shows cytotoxic activity against THP-1 human monocytic leukemic cell line, with an IC 50 of 4.0±0.08 μM |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (2S)-2-[5-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one |
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INCHI | InChI=1S/C25H28O6/c1-14(2)5-4-6-15(3)7-8-16-9-18(20(28)12-19(16)27)23-13-22(30)25-21(29)10-17(26)11-24(25)31-23/h5,7,9-12,23,26-29H,4,6,8,13H2,1-3H3/b15-7+/t23-/m0/s1 |
InChi Key | GJFHZVPRFLHEBR-KETROQBRSA-N |
Canonical SMILES | CC(=CCCC(=CCC1=CC(=C(C=C1O)O)C2CC(=O)C3=C(C=C(C=C3O2)O)O)C)C |
Isomeric SMILES | CC(=CCC/C(=C/CC1=CC(=C(C=C1O)O)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)/C)C |
Alternate CAS | 68401-05-8 |
PubChem CID | 6440408 |
Molecular Weight | 424.5 |
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