Kuwanon E - ≥96.0%, high purity , CAS No.68401-05-8

  • ≥96%
Item Number
K650940
Grouped product items
SKUSizeAvailabilityPrice Qty
K650940-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$286.90
K650940-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$857.90

Flavonoids Flavonones Phenols Polyphenols

Basic Description

Synonyms(S)-2-[5-[(E)-3,7-Dimethyl-2,6-octadienyl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one | HY-N3514 | (2S)-2-[5-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one | BDBM50291290 | (2S)-2-[
Specifications & Purity≥96%
Biochemical and Physiological MechanismsKuwanon E is a flavonoid isolated from Morus alba , cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

Kuwanon E is a flavonoid isolated from Morus alba , cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β

Form:Solid

IC50& Target:Kuwanon E shows cytotoxic activity against THP-1 human monocytic leukemic cell line, with an IC 50 of 4.0±0.08 μM

Associated Targets(Human)

ATP2A1 Tchem Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (55 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S)-2-[5-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one
INCHI InChI=1S/C25H28O6/c1-14(2)5-4-6-15(3)7-8-16-9-18(20(28)12-19(16)27)23-13-22(30)25-21(29)10-17(26)11-24(25)31-23/h5,7,9-12,23,26-29H,4,6,8,13H2,1-3H3/b15-7+/t23-/m0/s1
InChi Key GJFHZVPRFLHEBR-KETROQBRSA-N
Canonical SMILES CC(=CCCC(=CCC1=CC(=C(C=C1O)O)C2CC(=O)C3=C(C=C(C=C3O2)O)O)C)C
Isomeric SMILES CC(=CCC/C(=C/CC1=CC(=C(C=C1O)O)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)/C)C
Alternate CAS 68401-05-8
PubChem CID 6440408
Molecular Weight 424.5

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