KY02111 - ≥98%, high purity , CAS No.1118807-13-8

Item Number

K129803

Grouped product items
SKU	Size	Availability	Price	Qty
K129803-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$70.90
K129803-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$284.90

Promotes differentiation of hPSCs to cardiomyoctes. Wnt pathway inhibitor.

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Basic Description

Synonyms	EN300-1266069 \| UNII-6AXH36YF6M \| AS-16445 \| DTXSID80429194 \| MFCD08483062 \| KY02111 \| KY-02111 \| UNII-A4125MQ8RX \| 2-(3-(3,4-Dimethoxyphenyl)propanamido)-6-chlorobenzothiazole \| S7096 \| AM81229 \| C18H17ClN2O3S \| N-(6-Chloro-benzothiazol-2-yl)-3-(3,4-dime
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	KY02111 promotes differentiation of human pluripotent stem cells (hPSCs) to cardiomyocytes by inhibiting WNT signaling in hPSCs in a manner that is distinct from that of previously studied WNT inhibitors. The substantial (98%) differentiation of hPSCs to
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β. A Wnt inhibitor.

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-(6-chloro-1,3-benzothiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide
INCHI	InChI=1S/C18H17ClN2O3S/c1-23-14-7-3-11(9-15(14)24-2)4-8-17(22)21-18-20-13-6-5-12(19)10-16(13)25-18/h3,5-7,9-10H,4,8H2,1-2H3,(H,20,21,22)
InChi Key	LXFKEVQQSKQXPR-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C=C(C=C1)CCC(=O)NC2=NC3=C(S2)C=C(C=C3)Cl)OC
Isomeric SMILES	COC1=C(C=C(C=C1)CCC(=O)NC2=NC3=C(S2)C=C(C=C3)Cl)OC
WGK Germany	3
PubChem CID	8582409
Molecular Weight	376.86

Certificates

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2 results found

Lot Number	Certificate Type	Date	Item
J1515146	Certificate of Analysis	May 10, 2023	K129803
K1821169	Certificate of Analysis	Jul 18, 2022	K129803

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3

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Basic Description