Very potent and selective, non-competitive antagonist of the human Glukagon receptor (hGR). Binds with high affinity to human GR (IC50= 3.7 nM), and moderate affinity to murine and canine GRs (IC50values are 63 and 60 nM respectively). In contrast, displa
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Action Type
ANTAGONIST
Mechanism of action
Antagonist of glucagon receptor
Product Description
Product Describtion:
L-168049 is a potent, selective, orally active and non-competitive Glukagon receptor antagonist with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine Glukagon receptors, respectively.
D2311573