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L-365,260 - ≥99%(HPLC), high purity , CAS No.118101-09-0, Antagonist of CCK 1 receptor;Antagonist of CCK 2 receptor

Moligand™
≥99%(HPLC)

CAS#: 118101-09-0
Formula: C₂₄H₂₂N₄O₂
Molecular Weight: 398.46
PubChem CID: 5311201

Item Number

L287661

Grouped product items
SKU	Size	Availability	Price	Qty
L287661-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$157.90
L287661-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$256.90

Selective CCK2antagonist

View related series

CCK1 receptor Antagonist CCK2 receptor Antagonist

Basic Description

Synonyms	118101-09-0\|L-365260\|L-365,260\|N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea\|CHEBI:79548\|370JHF4586\|L 365260\|N-((3R)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-methylphenyl)urea\|Ur
Specifications & Purity	≥99%(HPLC)
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of CCK 1 receptor;Antagonist of CCK 2 receptor

Associated Targets

CCKAR Tclin Cholecystokinin receptor type A 1 Activities

Discover Target: CCKAR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCKBR Tclin Gastrin/cholecystokinin type B receptor 35 Activities

Discover Target: CCKBR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 2 Activities

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	1-[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea
INCHI	InChI=1S/C24H22N4O2/c1-16-9-8-12-18(15-16)25-24(30)27-22-23(29)28(2)20-14-7-6-13-19(20)21(26-22)17-10-4-3-5-11-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1
InChi Key	KDFQABSFVYLGPM-QFIPXVFZSA-N
Canonical SMILES	CC1=CC(=CC=C1)NC(=O)NC2C(=O)N(C3=CC=CC=C3C(=N2)C4=CC=CC=C4)C
Isomeric SMILES	CC1=CC(=CC=C1)NC(=O)N[C@H]2C(=O)N(C3=CC=CC=C3C(=N2)C4=CC=CC=C4)C
PubChem CID	5311201
Molecular Weight	398.46

PubChem CID

ChEMBL Ligand

CAS Registry No.

GPCRdb Ligand

Certificates

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2 results found

Lot Number	Certificate Type	Date	Item
J2225624	Certificate of Analysis	Oct 10, 2022	L287661
J2225625	Certificate of Analysis	Oct 10, 2022	L287661

Solubility

Solvent:DMSO, Max Conc. mg/mL: 39.85, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 39.85, Max Conc. mM: 100

Sensitivity

light sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS09
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H400:Very toxic to aquatic life
Precautionary Statements	P273:Avoid release to the environment. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.
RIDADR	UN2811-class6.1-PG3-EHS-Toxicsolids，organic，n.o.s.，HI:all

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