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L-701252 - 96%, high purity , CAS No.151057-13-5
NMDA antagonist; acts at glycine site
Basic Description
| Synonyms | 151057-13-5|L-701,252|7-chloro-3-(cyclopropanecarbonyl)-4-hydroxyquinolin-2(1H)-one|L-701252|7-Chloro-3-(cyclopropyl-carbonyl)-4-hydroxy-2(1H)-quinolinone|7-chloro-3-(cyclopropanecarbonyl)-4-hydroxy-1H-quinolin-2-one|NCGC00024741-01|Tocris-0705|Biomol-NT_ |
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| Specifications & Purity | ≥96% |
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| Biochemical and Physiological Mechanisms | An antagonist at the glycine-NMDA site (IC50= 420 nM). Also a potent systemic anticonvulsant. |
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| Storage Temp | Store at -20°C,Desiccated |
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| Shipped In | Ice chest + Ice pads |
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Names and Identifiers
| IUPAC Name | 7-chloro-3-(cyclopropanecarbonyl)-4-hydroxy-1H-quinolin-2-one |
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| INCHI | InChI=1S/C13H10ClNO3/c14-7-3-4-8-9(5-7)15-13(18)10(12(8)17)11(16)6-1-2-6/h3-6H,1-2H2,(H2,15,17,18) |
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| InChi Key | MXEFWCFPCLDOOG-UHFFFAOYSA-N |
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| Canonical SMILES | C1CC1C(=O)C2=C(C3=C(C=C(C=C3)Cl)NC2=O)O |
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| Isomeric SMILES | C1CC1C(=O)C2=C(C3=C(C=C(C=C3)Cl)NC2=O)O |
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| PubChem CID | 54687453 |
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| Molecular Weight | 263.68 |
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Chemical and Physical Properties
| Solubility | Solvent:DMSO, Max Conc. mg/mL: None, Max Conc. mM: 50 |
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