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Cannabinoid receptors
L-759633 - A solution of Methyl Acetate, high purity , CAS No.174627-50-0, Agonist of CB 2 receptor

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L-759633 - A solution of Methyl Acetate, high purity , CAS No.174627-50-0, Agonist of CB 2 receptor

Moligand™

A solution of Methyl Acetate

CAS#: 174627-50-0
Formula: C₂₆H₄₀O₂
Molecular Weight: 384.59
PubChem CID: 5311215

Item Number

L340921

Grouped product items
SKU	Size	Availability	Price	Qty
L340921-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$177.90

a high affinity and selective CB2 receptor agonist

View related series

CB2 receptor Agonist

Basic Description

Specifications & Purity	Moligand™, A solution of Methyl Acetate
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of CB 2 receptor
Product Description	L-759633 is a high affinity, selective CB2 receptor agonist (K\|i\|values are 6.4 and 1043 nM for CB2 and CB1 receptors respectively). This compound potently inhibits forskolin-stimulated cAMP production via CB2 receptors expressed in CHO cells (EC\|50\|= 8.1 nM).

Associated Targets(Human)

CNR2 Tchem Cannabinoid receptor 2 (3 Activities)

Discover Target: CNR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)

Discover Target: CNR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
INCHI	InChI=1S/C26H40O2/c1-8-9-10-11-14-25(3,4)19-16-22(27-7)24-20-15-18(2)12-13-21(20)26(5,6)28-23(24)17-19/h12,16-17,20-21H,8-11,13-15H2,1-7H3/t20-,21-/m1/s1
InChi Key	SUFMHSFGODDLKI-NHCUHLMSSA-N
Canonical SMILES	CCCCCCC(C)(C)C1=CC2=C(C3CC(=CCC3C(O2)(C)C)C)C(=C1)OC
Isomeric SMILES	CCCCCCC(C)(C)C1=CC2=C([C@@H]3CC(=CC[C@H]3C(O2)(C)C)C)C(=C1)OC
PubChem CID	5311215
MeSH Entry Terms	L 759633;L-759633;L759633
Molecular Weight	384.59

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	Soluble to 25 mM in DMSO and to 50 mM in Ethanol

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