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L-759633 - A solution of Methyl Acetate, high purity , CAS No.174627-50-0, Agonist of CB 2 receptor
a high affinity and selective CB2 receptor agonist
Basic Description Specifications & Purity Moligand™, A solution of Methyl Acetate Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of CB 2 receptor Product Description L-759633 is a high affinity, selective CB2 receptor agonist (K|i|values are 6.4 and 1043 nM for CB2 and CB1 receptors respectively). This compound potently inhibits forskolin-stimulated cAMP production via CB2 receptors expressed in CHO cells (EC|50|= 8.1 nM).
Names and Identifiers IUPAC Name (6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene INCHI InChI=1S/C26H40O2/c1-8-9-10-11-14-25(3,4)19-16-22(27-7)24-20-15-18(2)12-13-21(20)26(5,6)28-23(24)17-19/h12,16-17,20-21H,8-11,13-15H2,1-7H3/t20-,21-/m1/s1 InChi Key SUFMHSFGODDLKI-NHCUHLMSSA-N Canonical SMILES CCCCCCC(C)(C)C1=CC2=C(C3CC(=CCC3C(O2)(C)C)C)C(=C1)OC Isomeric SMILES CCCCCCC(C)(C)C1=CC2=C([C@@H]3CC(=CC[C@H]3C(O2)(C)C)C)C(=C1)OC PubChem CID 5311215 MeSH Entry Terms L 759633;L-759633;L759633 Molecular Weight 384.59
Chemical and Physical Properties Solubility Soluble to 25 mM in DMSO and to 50 mM in Ethanol
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