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L-AP5 - ≥99%(HPLC), high purity , CAS No.79055-67-7
Potent and selective NMDA antagonist; less active form ofDL-AP5
Basic Description
| Synonyms | CS-0020422 | SR-01000597696-1 | 5-phosphono-L-norvaline | (S)-2-amino-5-phosphonopentanoicacid | L-AP5 | (s)-2-amino-5-phosphonovaleric acid | D93187 | L-(+)-2-Amino-5-phosphonopentanoic acid | L(+)-2-Amino-5-phosphonopentanoic acid | 2-Amino-5-phosphono- |
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| Specifications & Purity | ≥99%(HPLC) |
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| Biochemical and Physiological Mechanisms | NMDA antagonist. Also agonist at quisqualate-sensitized AP6 site, where it is more potent than the isomerD-AP5.DL MixtureandD-isomeralso available. |
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| Storage Temp | Store at -20°C,Argon charged |
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| Shipped In | Ice chest + Ice pads |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (2S)-2-amino-5-phosphonopentanoic acid |
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| INCHI | InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/t4-/m0/s1 |
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| InChi Key | VOROEQBFPPIACJ-BYPYZUCNSA-N |
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| Canonical SMILES | C(CC(C(=O)O)N)CP(=O)(O)O |
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| Isomeric SMILES | C(C[C@@H](C(=O)O)N)CP(=O)(O)O |
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| PubChem CID | 1617110 |
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| Molecular Weight | 197.13 |
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Chemical and Physical Properties
| Solubility | Solvent:water, Max Conc. mg/mL: None, Max Conc. mM: 100 |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
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| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
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| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
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