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L-AP5 - ≥99%(HPLC), high purity , CAS No.79055-67-7

≥99%(HPLC)

CAS#: 79055-67-7
Formula: C₅H₁₂NO₅P
Molecular Weight: 197.13
PubChem CID: 1617110

Item Number

L286955

Grouped product items
SKU	Size	Availability	Price
L286955-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$138.90
L286955-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$219.90
L286955-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$488.90
L286955-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$899.90

Potent and selective NMDA antagonist; less active form ofDL-AP5

Basic Description

Synonyms	L-AP5\|(S)-2-amino-5-phosphonopentanoic acid\|79055-67-7\|5-phosphono-L-norvaline\|(2S)-2-amino-5-phosphonopentanoic acid\|CHEMBL71898\|(S)-2-amino-5-phosphonopentanoicacid\|2-Amino-5-phosphono-pentanoic acid\|L-2-Amino-5-phosphopentanoic acid\|Tocris-0107\|SCHEMBL
Specifications & Purity	≥99%(HPLC)
Biochemical and Physiological Mechanisms	NMDA antagonist. Also agonist at quisqualate-sensitized AP6 site, where it is more potent than the isomerD-AP5.DL MixtureandD-isomeralso available.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

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CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

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CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

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CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

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CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

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USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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GRM1 Tchem Metabotropic glutamate receptor 1 0 Activities

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GRM2 Tchem Metabotropic glutamate receptor 2 0 Activities

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GRM4 Tchem Metabotropic glutamate receptor 4 0 Activities

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GRM5 Tchem Metabotropic glutamate receptor 5 0 Activities

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GRIN3A Tclin Glutamate receptor ionotropic, NMDA 3A 0 Activities

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GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A 0 Activities

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KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

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Names and Identifiers

IUPAC Name	(2S)-2-amino-5-phosphonopentanoic acid
INCHI	InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/t4-/m0/s1
InChi Key	VOROEQBFPPIACJ-BYPYZUCNSA-N
Canonical SMILES	C(CC(C(=O)O)N)CP(=O)(O)O
Isomeric SMILES	C(C[C@@H](C(=O)O)N)CP(=O)(O)O
PubChem CID	1617110
Molecular Weight	197.13

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

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