Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

L-Arginine hydrochloride - EP,JP,USP grade,≥98.5%,for cell culture, high purity , CAS No.1119-34-2

1 Citations
Item Number
A103485
Grouped product items
SKUSizeAvailabilityPrice Qty
A103485-100g
100g
In stock
$71.90
A103485-500g
500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$323.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Nitrogen donor for the synthesis of nitric oxide

Basic Description

Synonyms(S)-2-Amino-5-guanidinopentanoic acid hydrochloride | L-ARGININE HCL | L-Arginine monohydrochloride, BioUltra, >=99.5% (AT) | NSC-203450 | ARGININE HYDROCHLORIDE [ORANGE BOOK] | ARGININE HYDROCHLORIDE [USAN] | L-ARGININE HYDROCHLORIDE [JAN] | H-Arg-OH.HCl
Specifications & PurityPharmPure™, USP, JP, Ph.Eur., for cell culture, ≥98.5%
Biochemical and Physiological MechanismsSubstrate of nitric oxide synthase (NOS), which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.
Storage TempArgon charged,Desiccated
Shipped InNormal
Gradefor cell culture, JP, Ph.Eur., PharmPure™, USP
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

DRD1 Tclin D(1A) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ESR1 Tclin Estrogen receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH3 Tclin Histamine H3 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A2 Tclin Sodium-dependent noradrenaline transporter (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A3 Tclin Sodium-dependent dopamine transporter (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A4 Tclin Sodium-dependent serotonin transporter (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PGR Tclin Progesterone receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE4A Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD3 Tclin D(3) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDR Tclin Vascular endothelial growth factor receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ACHE Tclin Acetylcholinesterase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2A Tclin Alpha-2A adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1A Tclin Alpha-1A adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AR Tclin Androgen receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAOA Tclin Amine oxidase [flavin-containing] A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA3 Tchem Adenosine receptor A3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TBXA2R Tclin Thromboxane A2 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
F2 Tclin Prothrombin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
OPRM1 Tclin Mu-type opioid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 (1034 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride
INCHI InChI=1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
InChi Key KWTQSFXGGICVPE-WCCKRBBISA-N
Canonical SMILES Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
Isomeric SMILES C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl
WGK Germany 1
Alternate CAS 15595-35-4
PubChem CID 66250
Molecular Weight 210.66
Beilstein 6099937

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
H2415076Certificate of AnalysisJul 27, 2024 A103485
E2428029Certificate of AnalysisMay 11, 2024 A103485
E2428030Certificate of AnalysisMay 11, 2024 A103485
E2428031Certificate of AnalysisMay 11, 2024 A103485
L2311150Certificate of AnalysisDec 12, 2023 A103485
D23061236Certificate of AnalysisApr 08, 2023 A103485
B2301186Certificate of AnalysisOct 12, 2022 A103485
K2204216Certificate of AnalysisOct 12, 2022 A103485
K2204217Certificate of AnalysisOct 12, 2022 A103485

Chemical and Physical Properties

SolubilitySoluble in water. Slightly soluble in hot alcohol.
SensitivityLight & Moisture Sensitive.
Specific Rotation[α]23 ° (C=8, HCl(1+1))
Melt Point(°C)226-230°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 1
Merck Index 780

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Nα-Fmoc-Nω,ω-dimethyl-L-arginine hydrochloride
    Nα-Fmoc-Nω,ω-dimethyl-L-arginine hydrochloride

    Starting at $171.90

  2. L-Arginine-15N4 hydrochloride
    L-Arginine-15N4 hydrochloride

    Starting at $152.90

  3. L-Arginine hydrochloride - 10mM in Water, used for , CAS No. 1119-34-2, by Aladdin Scientific
    L-Arginine hydrochloride
    • 10mM in Water

    Starting at $69.90

  4. N2-[[5-(Dimethylamino)-1-Naphthalenyl]Sulfonyl]-L-Arginine
    N2-[[5-(Dimethylamino)-1-Naphthalenyl]Sulfonyl]-L-Arginine
    • ≥98%

    Starting at $133.90

  5. Nomega-Allyl-L-arginine hydrochloride - ≥99%, used for , CAS No. 139461-37-3, by Aladdin Scientific
    Nomega-Allyl-L-arginine hydrochloride
    • ≥99%

    Starting at $128.90

  6. MTH-DL-Arginine hydrochloride
    MTH-DL-Arginine hydrochloride

    Starting at $108.90

  7. L-Arginine hydrochloride - 99%, used for , CAS No. 1119-34-2, by Aladdin Scientific
    L-Arginine hydrochloride
    • ≥99%

    Starting at $11.90

  8. Nω-Propyl-L-arginine hydrochloride
    Nω-Propyl-L-arginine hydrochloride
    • ≥98%(HPLC)

    Starting at $39.90

  9. L(+)-Arginine hydrochloride - USP, used for , CAS No. 1119-34-2, by Aladdin Scientific
    L(+)-Arginine hydrochloride

    Starting at $85.90

  10. Nomega-Methyl-L-arginine hydrochloride - ≥98%, used for , CAS No. 156706-47-7, by Aladdin Scientific
    Nomega-Methyl-L-arginine hydrochloride
    • ≥98%

    Starting at $332.90

  11. Poly(L-arginine hydrochloride) Thiol
    Poly(L-arginine hydrochloride) Thiol
    As low as $1,260.90
  12. Cbz-L-Arginine hydrochloride
    Cbz-L-Arginine hydrochloride
    • ≥98%

    Starting at $23.90

  13. Nω-Hydroxy-nor-L-Arginine Dihydrochloride - ≥97%, used for , CAS No. 291758-32-2, by Aladdin Scientific
    Nω-Hydroxy-nor-L-Arginine Dihydrochloride

    Starting at $266.90

  14. Nomega-Propyl-L-arginine hydrochloride - ≥98%, used for , CAS No. 137361-05-8, by Aladdin Scientific
    Nomega-Propyl-L-arginine hydrochloride

    Starting at $128.90

  15. Poly(L-arginine hydrochloride) Azide
    Poly(L-arginine hydrochloride) Azide
    As low as $1,260.90
  16. Boc-Arg-OH hydrochloride
    Boc-Arg-OH hydrochloride
    • ≥98%

    Starting at $21.90

  17. DL-Arginine Hydrochloride - 98%, used for , CAS No. 32042-43-6, by Aladdin Scientific
    DL-Arginine Hydrochloride
    • ≥98%

    Starting at $28.90

  18. L-Arginine-15N4 hydrochloride
    L-Arginine-15N4 hydrochloride

    Starting at $481.90

  19. NG-Amino-L-arginine hydrochloride
    NG-Amino-L-arginine hydrochloride

    Starting at $47.90

  20. L-Arginine hydrochloride - 98%, used for , CAS No. 1119-34-2, by Aladdin Scientific
    L-Arginine hydrochloride
    • ≥98%

    Starting at $17.90

Citations of This Product

1. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge.  (2024)  Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats.  SAUDI PHARMACEUTICAL JOURNAL,  32  (101934).  [PMID:38223203]

References

1. Wu X et al..  (2020)  Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase..  Cell Chem Biol,  27  (5): (571-585.e6).  [PMID:32243810]
2. Nina C Hubner,Matthias Mann.  (2010-12-28)  Extracting gene function from protein-protein interactions using Quantitative BAC InteraCtomics (QUBIC)..  Methods (San Diego, Calif.),  53  ((4)): (453-459).  [PMID:21184827]
3. Rahul D Sheth,Mi Jin,Bharat V Bhut,Zhengjian Li,Wilfred Chen,Steven M Cramer.  (2014-03-07)  Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP-Z stimuli responsive biopolymer..  Biotechnology and bioengineering,  111  ((8)): (1595-1603).  [PMID:24595842]
4. Lucie Holubova,Lucie Korecka,Stepan Podzimek,Veronika Moravcova,Jana Rotkova,Tereza Ehlova,Vladimir Velebny,Zuzana Bilkova.  (2014-08-19)  Enhanced multiparametric hyaluronan degradation for production of molar-mass-defined fragments..  Carbohydrate polymers,  112  (271-276).  [PMID:25129744]
5. Nivaldo Ribeiro Villela,Ana Olimpia Maia Teixeira dos Santos,Marcos Lopes de Miranda,Eliete Bouskela.  (2014-08-26)  Fluid resuscitation therapy in endotoxemic hamsters improves survival and attenuates capillary perfusion deficits and inflammatory responses by a mechanism related to nitric oxide..  Journal of translational medicine,  12  (232-232).  [PMID:25151363]
6. Carolina Di Somma,Alessandro Ciresi,Marco C Amato,Silvia Savastano,Maria Cristina Savanelli,Elisabetta Scarano,Annamaria Colao,Carla Giordano.  (2014-11-10)  Alteration of the growth hormone axis, visceral fat dysfunction, and early cardiometabolic risk in adults: the role of the visceral adiposity index..  Endocrine,  49  ((2)): (492-502).  [PMID:25381601]
7. X Zheng,X Cheng,L Wang,W Qiu,S Wang,Y Zhou,M Li,Y Li,L Cheng,J Li,X Zhou,X Xu.  (2014-12-06)  Combinatorial effects of arginine and fluoride on oral bacteria..  Journal of dental research,  94  ((2)): (344-353).  [PMID:25477312]
8. Hao Zheng, Cui Tang, Chunhua Yin,.  (2014-12-24)  Exploring advantages/disadvantages and improvements in overcoming gene delivery barriers of amino acid modified trimethylated chitosan..  Pharmaceutical research,  32  ((6)): ( 2038-2050 ).  [PMID:25534683]
9. C B Christiansen,B Svendsen,J J Holst.  (2015-01-21)  The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas..  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,  47  ((7)): (537-543).  [PMID:25602348]
10. Renata V Tiradentes,Cintia H Santuzzi,Erick Rg Claudio,Vinicius Mengal,Nyam F Silva,Henrique A F Neto,Nazaré S Bissoli,Glaucia R Abreu,Sonia A Gouvea.  (2015-03-06)  Combined Aliskiren and L-arginine treatment reverses renovascular hypertension in an animal model..  Hypertension research : official journal of the Japanese Society of Hypertension,  38  ((7)): (471-477).  [PMID:25740291]
11. Yumiko Mizukoshi,Koh Takeuchi,Misa Arutaki,Takeshi Takizawa,Hiroyuki Hanzawa,Hideo Takahashi,Ichio Shimada.  (2015-03-12)  Suppression of problematic compound oligomerization by cosolubilization of nondetergent sulfobetaines..  ChemMedChem,  10  ((4)): (736-741).  [PMID:25760302]
12. Jenna Gallie,Eric Libby,Frederic Bertels,Philippe Remigi,Christian B Jendresen,Gayle C Ferguson,Nicolas Desprat,Marieke F Buffing,Uwe Sauer,Hubertus J E Beaumont,Jan Martinussen,Mogens Kilstrup,Paul B Rainey.  (2015-03-13)  Bistability in a metabolic network underpins the de novo evolution of colony switching in Pseudomonas fluorescens..  PLoS biology,  13  ((3)): (e1002109-e1002109).  [PMID:25763575]
13. L Rascón-Valenzuela,C Velázquez,A Garibay-Escobar,L A Medina-Juárez,W Vilegas,R E Robles-Zepeda.  (2015-06-13)  Antiproliferative activity of cardenolide glycosides from Asclepias subulata..  Journal of ethnopharmacology,  171  (280-286).  [PMID:26068432]
14. Jun Yeul Lim,Nam Ah Kim,Dae Gon Lim,Ki Hyun Kim,Shavron Hada,Seong Hoon Jeong.  (2015-07-19)  Evaluation of etanercept degradation under oxidative stress and potential protective effects of various amino acids..  International journal of pharmaceutics,  492  ((1-2)): (127-136).  [PMID:26187168]
15. Caroline Nava,Johanna Rupp,Jean-Paul Boissel,Cyril Mignot,Agnès Rastetter,Claire Amiet,Aurélia Jacquette,Céline Dupuits,Delphine Bouteiller,Boris Keren,Merle Ruberg,Anne Faudet,Diane Doummar,Anne Philippe,Didier Périsse,Claudine Laurent,Nicolas Lebrun,Vincent Guillemot,Jamel Chelly,David Cohen,Delphine Héron,Alexis Brice,Ellen I Closs,Christel Depienne.  (2015-07-29)  Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders..  Amino acids,  47  ((12)): (2647-2658).  [PMID:26215737]
16. N E Paul,R Lösel,K Hemmrich,D Goy,N Pallua,D Klee.  (2015-09-26)  L-arginine and arginine ethyl ester enhance proliferation of endothelial cells and preadipocytes - how an arginine ethyl ester-releasing biomaterial could support endothelial cell growth in tissue engineering..  Bio-medical materials and engineering,  25  ((3)): (289-297).  [PMID:26407115]
17. Xiaofei Zhang,Arne H Smits,Gabrielle B A van Tilburg,Pascal W T C Jansen,Matthew M Makowski,Huib Ovaa,Michiel Vermeulen.  (2017-02-14)  An Interaction Landscape of Ubiquitin Signaling..  Molecular cell,  65  ((5)): (941-955).  [PMID:28190767]
18. Tzu-Yu Liu,Hector H Huang,Diamond Wheeler,Yichen Xu,James A Wells,Yun S Song,Arun P Wiita.  (2017-06-06)  Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics..  Cell systems,  4  ((6)): (636-644).  [PMID:28578850]
19. Raghu R Edupuganti,Simon Geiger,Rik G H Lindeboom,Hailing Shi,Phillip J Hsu,Zhike Lu,Shuang-Yin Wang,Marijke P A Baltissen,Pascal W T C Jansen,Martin Rossa,Markus Müller,Hendrik G Stunnenberg,Chuan He,Thomas Carell,Michiel Vermeulen.  (2017-09-05)  N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis..  Nature structural & molecular biology,  24  ((10)): (870-878).  [PMID:28869609]
20. Katharina Overlack,Tanja Bange,Florian Weissmann,Alex C Faesen,Stefano Maffini,Ivana Primorac,Franziska Müller,Jan-Michael Peters,Andrea Musacchio.  (2017-09-26)  BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling..  Current biology : CB,  27  ((19)): (2915-2927).  [PMID:28943088]
21. Sebastian Markmiller,Sahar Soltanieh,Kari L Server,Raymond Mak,Wenhao Jin,Mark Y Fang,En-Ching Luo,Florian Krach,Dejun Yang,Anindya Sen,Amit Fulzele,Jacob M Wozniak,David J Gonzalez,Mark W Kankel,Fen-Biao Gao,Eric J Bennett,Eric Lécuyer,Gene W Yeo.  (2018-01-27)  Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules..  Cell,  172  ((3)): (590-604).  [PMID:29373831]
22. Chloe R McDonald,Lindsay S Cahill,Joel L Gamble,Robyn Elphinstone,Lisa M Gazdzinski,Kathleen J Y Zhong,Adrienne C Philson,Mwayiwawo Madanitsa,Linda Kalilani-Phiri,Victor Mwapasa,Feiko O Ter Kuile,John G Sled,Andrea L Conroy,Kevin C Kain.  (2018-03-09)  Malaria in pregnancy alters l-arginine bioavailability and placental vascular development..  Science translational medicine,  10  ((431)):   [PMID:29514999]
23. Charlotte B Christiansen,Sara J Lind,Berit Svendsen,Emilie Balk-Møller,Tina Dahlby,Rune E Kuhre,Bolette Hartmann,Thomas Mandrup-Poulsen,Carolyn F Deacon,Nicolai J Wewer Albrechtsen,Jens J Holst.  (2018-07-08)  Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice..  Physiological reports,  6  ((13)): (e13788-e13788).  [PMID:29981198]
24. Katie Nightingale,Kai-Min Lin,Benjamin J Ravenhill,Colin Davies,Luis Nobre,Ceri A Fielding,Eva Ruckova,Alice Fletcher-Etherington,Lior Soday,Hester Nichols,Daniel Sugrue,Eddie C Y Wang,Pablo Moreno,Yagnesh Umrania,Edward L Huttlin,Robin Antrobus,Andrew J Davison,Gavin W G Wilkinson,Richard J Stanton,Peter Tomasec,Michael P Weekes.  (2018-08-21)  High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms..  Cell host & microbe,  24  ((3)): (447-460).  [PMID:30122656]
25. Alexandra K Davies,Daniel N Itzhak,James R Edgar,Tara L Archuleta,Jennifer Hirst,Lauren P Jackson,Margaret S Robinson,Georg H H Borner.  (2018-09-29)  AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A..  Nature communications,  9  ((1)): (3958-3958).  [PMID:30262884]
26. John M E Nichols,Peggy Paschke,Sew Peak-Chew,Thomas D Williams,Luke Tweedy,Mark Skehel,Elaine Stephens,Jonathan R Chubb,Robert R Kay.  (2019-01-08)  The Atypical MAP Kinase ErkB Transmits Distinct Chemotactic Signals through a Core Signaling Module..  Developmental cell,  48  ((4)): (491-505).  [PMID:30612939]
27. Yahui Yan,Claudia Rato,Lukas Rohland,Steffen Preissler,David Ron.  (2019-02-03)  MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP..  Nature communications,  10  ((1)): (541-541).  [PMID:30710085]
28. Xazmin H Lowman,Eric A Hanse,Ying Yang,Mari B Ishak Gabra,Thai Q Tran,Haiqing Li,Mei Kong.  (2019-03-14)  p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake..  Cell reports,  26  ((11)): (3051-3060).  [PMID:30865893]
29. Daniele Musiani,Jabez Bok,Enrico Massignani,Liling Wu,Tommaso Tabaglio,Marica Rosaria Ippolito,Alessandro Cuomo,Umut Ozbek,Habiba Zorgati,Umesh Ghoshdastider,Robert C Robinson,Ernesto Guccione,Tiziana Bonaldi.  (2019-04-04)  Proteomics profiling of arginine methylation defines PRMT5 substrate specificity..  Science signaling,  12  ((575)):   [PMID:30940768]
30. Natalia A Cherepanova,Sergey V Venev,John D Leszyk,Scott A Shaffer,Reid Gilmore.  (2019-07-13)  Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites..  The Journal of cell biology,  218  ((8)): (2782-2796).  [PMID:31296534]
31. Anne Ørgaard,Sara Lind Jepsen,Jens Juul Holst.  (2019-08-31)  Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice..  Islets,  11  ((5)): (103-111).  [PMID:31469342]
32. Yu-Hsin Chang,Megumi C Katoh,Ahmed M Abdellatif,Guli Xiafukaiti,Abdelaziz Elzeftawy,Masami Ojima,Seiya Mizuno,Akihiro Kuno,Satoru Takahashi.  (2019-12-04)  Uncovering the role of MAFB in glucagon production and secretion in pancreatic α-cells using a new α-cell-specific Mafb conditional knockout mouse model..  Experimental animals,  69  ((2)): (178-188).  [PMID:31787710]
33. Zhong-Qiu Yu,Ling-Ling Sun,Zhao-Di Jiang,Xiao-Man Liu,Dan Zhao,Hai-Tao Wang,Wan-Zhong He,Meng-Qiu Dong,Li-Lin Du.  (2020-01-17)  Atg38-Atg8 interaction in fission yeast establishes a positive feedback loop to promote autophagy..  Autophagy,  16  ((11)): (2036-2051).  [PMID:31941401]
34. Daniele Musiani,Roberto Giambruno,Enrico Massignani,Marica Rosaria Ippolito,Marianna Maniaci,Sriganesh Jammula,Daria Manganaro,Alessandro Cuomo,Luciano Nicosia,Diego Pasini,Tiziana Bonaldi.  (2020-01-30)  PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin..  Cell reports,  30  ((4)): (1208-1222).  [PMID:31995759]
35. Mark Jelcic,Ke Wang,King Lam Hui,Xiao-Chuan Cai,Balázs Enyedi,Minkui Luo,Philipp Niethammer.  (2020-06-11)  A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome..  Cell chemical biology,  27  ((8)): (1073-1083).  [PMID:32521230]
36. Patrycja Kozik,Marine Gros,Daniel N Itzhak,Leonel Joannas,Sandrine Heurtebise-Chrétien,Patrycja A Krawczyk,Pablo Rodríguez-Silvestre,Andrés Alloatti,Joao Gamelas Magalhaes,Elaine Del Nery,Georg H H Borner,Sebastian Amigorena.  (2020-07-16)  Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity..  Cell reports,  32  ((2)): (107905-107905).  [PMID:32668257]
37. Jenna K Rimel,Zachary C Poss,Benjamin Erickson,Zachary L Maas,Christopher C Ebmeier,Jared L Johnson,Tim-Michael Decker,Tomer M Yaron,Michael J Bradley,Kristin B Hamman,Shanhu Hu,Goran Malojcic,Jason J Marineau,Peter W White,Martine Brault,Limei Tao,Patrick DeRoy,Christian Clavette,Shraddha Nayak,Leah J Damon,Ines H Kaltheuner,Heeyoun Bunch,Lewis C Cantley,Matthias Geyer,Janet Iwasa,Robin D Dowell,David L Bentley,William M Old,Dylan J Taatjes.  (2020-10-17)  Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription..  Genes & development,  34  ((21-22)): (1452-1473).  [PMID:33060135]
38. David Tobys,Lisa Maria Kowalski,Eva Cziudaj,Stefan Müller,Peter Zentis,Elke Pach,Paola Zigrino,Tobias Blaeske,Stefan Höning.  (2020-11-24)  Inhibition of clathrin-mediated endocytosis by knockdown of AP-2 leads to alterations in the plasma membrane proteome..  Traffic (Copenhagen, Denmark),  22  ((1-2)): (6-22).  [PMID:33225555]
39. Chengjie Chen,Tao Peng.  (2020-12-31)  Protocol for Site-Specific Photo-Crosslinking Proteomics to Identify Protein-Protein Interactions in Mammalian Cells..  STAR protocols,  1  ((3)): (100109-100109).  [PMID:33377005]
40. Nan Wu,Xiao-Fan Xu,Jia-Qi Xin,Jian-Wei Fan,Yuan-Yuan Wei,Qing-Xia Peng,Li-Fang Duan,Wei Wang,Hong Zhang.  (2020-12-31)  The effects of nuclear factor-kappa B in pancreatic stellate cells on inflammation and fibrosis of chronic pancreatitis..  Journal of cellular and molecular medicine,  25  ((4)): (2213-2227).  [PMID:33377616]
41. Alissa D Guarnaccia,Kristie L Rose,Jing Wang,Bin Zhao,Tessa M Popay,Christina E Wang,Kiana Guerrazzi,Salisha Hill,Chase M Woodley,Tyler J Hansen,Shelly L Lorey,J Grace Shaw,William G Payne,April M Weissmiller,Edward T Olejniczak,Stephen W Fesik,Qi Liu,William P Tansey.  (2021-01-21)  Impact of WIN site inhibitor on the WDR5 interactome..  Cell reports,  34  ((3)): (108636-108636).  [PMID:33472061]
42. Franziska Mueller,Alexandra Friese,Claudio Pathe,Richard Cardoso da Silva,Kenny Bravo Rodriguez,Andrea Musacchio,Tanja Bange.  (2021-02-02)  Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization..  Science advances,  7  ((3)):   [PMID:33523899]
43. Shota Someya,Shugo Tohyama,Kotaro Kameda,Sho Tanosaki,Yuika Morita,Kazunori Sasaki,Moon-Il Kang,Yoshikazu Kishino,Marina Okada,Hidenori Tani,Yusuke Soma,Kazuaki Nakajima,Tomohiko Umei,Otoya Sekine,Taijun Moriwaki,Hideaki Kanazawa,Eiji Kobayashi,Jun Fujita,Keiichi Fukuda.  (2021-02-23)  Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells..  iScience,  24  ((2)): (102090-102090).  [PMID:33615198]
44. Sheng-Chieh Hsu,Chia-Lin Chen,Mei-Ling Cheng,Cheng-Ying Chu,Chun A Changou,Yen-Ling Yu,Shauh-Der Yeh,Tse-Chun Kuo,Cheng-Chin Kuo,Chih-Pin Chuu,Chien-Feng Li,Lu-Hai Wang,Hong-Wu Chen,Yun Yen,David K Ann,Hung-Jung Wang,Hsing-Jien Kung.  (2021-06-24)  Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes..  Theranostics,  11  ((15)): (7527-7545).  [PMID:34158865]
45. Jaehyek Choi,Cun Li,Thomas J McDonald,Anthony Comuzzie,Vicki Mattern,Peter W Nathanielsz.  (2011-06-10)  Emergence of insulin resistance in juvenile baboon offspring of mothers exposed to moderate maternal nutrient reduction..  American journal of physiology. Regulatory, integrative and comparative physiology,  301  ((3)): (R757-R762).  [PMID:21653880]
46. Monica Soldi,Tiziana Bonaldi.  (2013-01-16)  The proteomic investigation of chromatin functional domains reveals novel synergisms among distinct heterochromatin components..  Molecular & cellular proteomics : MCP,  12  ((3)): (764-780).  [PMID:23319141]
47. Li-Qi Xie,Ai-Ying Nie,Shu-Jun Yang,Chao Zhao,Lei Zhang,Peng-Yuan Yang,Hao-Jie Lu.  (2014-07-17)  Global in vivo terminal amino acid labeling for exploring differential expressed proteins induced by dialyzed serum cultivation..  The Analyst,  139  ((18)): (4497-4504).  [PMID:25028700]
48. David Goodwin,Barry Rosenzweig,Jun Zhang,Lin Xu,Sharron Stewart,Karol Thompson,Rodney Rouse.  (2014-07-26)  Evaluation of miR-216a and miR-217 as potential biomarkers of acute pancreatic injury in rats and mice..  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals,  19  ((6)): (517-529).  [PMID:25059555]
49. Daniel N Itzhak,Stefka Tyanova,Jürgen Cox,Georg Hh Borner.  (2016-06-10)  Global, quantitative and dynamic mapping of protein subcellular localization..  eLife,  5    [PMID:27278775]
50. Simon D Brown,Alexander Lorenz.  (2017-03-30)  Single-step Marker Switching in Schizosaccharomyces pombe Using a Lithium Acetate Transformation Protocol..  Bio-protocol,  6  ((24)):   [PMID:28352647]
51. Nicholas Johnson,Jana Březinová,Elaine Stephens,Emma Burbridge,Matthew Freeman,Colin Adrain,Kvido Strisovsky.  (2017-08-06)  Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis..  Scientific reports,  7  ((1)): (7283-7283).  [PMID:28779096]
52. N Pospiech,H Cibis,L Dietrich,F Müller,T Bange,S Hennig.  (2018-02-13)  Identification of novel PANDAR protein interaction partners involved in splicing regulation..  Scientific reports,  8  ((1)): (2798-2798).  [PMID:29434205]
53. Greta Caprara,Elena Prosperini,Viviana Piccolo,Gianluca Sigismondo,Alessia Melacarne,Alessandro Cuomo,Mark Boothby,Maria Rescigno,Tiziana Bonaldi,Gioacchino Natoli.  (2018-03-04)  PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN-Inducible Proteins..  Journal of immunology (Baltimore, Md. : 1950),  200  ((7)): (2439-2454).  [PMID:29500242]
54. Constance Alabert,Carolin Loos,Moritz Voelker-Albert,Simona Graziano,Ignasi Forné,Nazaret Reveron-Gomez,Lea Schuh,Jan Hasenauer,Carsten Marr,Axel Imhof,Anja Groth.  (2020-01-30)  Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes..  Cell reports,  30  ((4)): (1223-1234).  [PMID:31995760]
55. Maria Emilia Taskinen,Elisa Närvä,James R W Conway,Laura Soto Hinojosa,Sergio Lilla,Anja Mai,Nicola De Franceschi,Laura L Elo,Robert Grosse,Sara Zanivan,Jim C Norman,Johanna Ivaska.  (2020-04-21)  MASTL promotes cell contractility and motility through kinase-independent signaling..  The Journal of cell biology,  219  ((6)):   [PMID:32311005]
56. Colin M Hammond,Hongyu Bao,Ivo A Hendriks,Massimo Carraro,Alberto García-Nieto,Yanhong Liu,Nazaret Reverón-Gómez,Christos Spanos,Liu Chen,Juri Rappsilber,Michael L Nielsen,Dinshaw J Patel,Hongda Huang,Anja Groth.  (2021-04-16)  DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network..  Molecular cell,  81  ((12)): (2533-2548).  [PMID:33857403]
57. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge.  (2024)  Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats.  SAUDI PHARMACEUTICAL JOURNAL,  32  (101934).  [PMID:38223203]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.