Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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A103486-25g | 25g | In stock | $11.90 | |
A103486-100g | 100g | In stock | $32.90 | |
A103486-500g | 500g | In stock | $99.90 |
Synonyms | (S)-2-Amino-5-guanidinopentanoic acid hydrochloride | L-ARGININE HCL | L-Arginine monohydrochloride, BioUltra, >=99.5% (AT) | NSC-203450 | ARGININE HYDROCHLORIDE [ORANGE BOOK] | ARGININE HYDROCHLORIDE [USAN] | L-ARGININE HYDROCHLORIDE [JAN] | H-Arg-OH.HCl |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | 一氧化氮合成酶的底物,可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。 |
Storage Temp | Argon charged,Desiccated |
Shipped In | Normal |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|---|---|---|---|---|---|---|
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | FDA: [1] | |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] | |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | FDA: [1] | |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] | |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] | |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | PubMed: [1] | |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | Melagatran, the active molecule, binds to the arginine side pocket of thrombin. | |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | ||
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | Exosite I region | PubMed: [1] |
Thrombin inhibitor | INHIBITOR | ALA204 | Thrombin | SINGLE PROTEIN | Homo sapiens | PubMed: [1] |
IUPAC Name | (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride |
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INCHI | InChI=1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1 |
InChi Key | KWTQSFXGGICVPE-WCCKRBBISA-N |
Canonical SMILES | Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O |
Isomeric SMILES | C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl |
WGK Germany | 1 |
Alternate CAS | 15595-35-4 |
PubChem CID | 66250 |
Molecular Weight | 210.66 |
Beilstein | 6099937 |
Find and download the COA for your product by matching the lot number on the packaging.
23 results found
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
Certificate of Analysis | Jan 07, 2025 | A103486 | |
Certificate of Analysis | Jul 29, 2024 | A103486 | |
Certificate of Analysis | Jul 29, 2024 | A103486 | |
Certificate of Analysis | Jul 29, 2024 | A103486 | |
Certificate of Analysis | Apr 22, 2024 | A103486 | |
Certificate of Analysis | Apr 22, 2024 | A103486 | |
Certificate of Analysis | Apr 10, 2024 | A103486 | |
Certificate of Analysis | Nov 18, 2023 | A103486 | |
Certificate of Analysis | Nov 18, 2023 | A103486 | |
Certificate of Analysis | Nov 18, 2023 | A103486 |
Solubility | Easily soluble in water and formic acid, slightly soluble in ethanol, insoluble in ether. |
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Sensitivity | Moisture sensitive. |
Specific Rotation[α] | 23 ° (C=8, HCl(1+1)) |
Melt Point(°C) | 226-230°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 1 |
Merck Index | 780 |
Starting at $69.90
Starting at $71.90
Starting at $85.90
Starting at $17.90
Starting at $314.90
1. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge. (2024) Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. SAUDI PHARMACEUTICAL JOURNAL, 32 (101934). [PMID:38223203] [10.1016/j.jsps.2023.101934] |
2. Yanbo Wang, Yongzheng Wang, Jian Chen, Shigenobu Koseki, Qing Yang, Hejun Yu, Linglin Fu. (2021) Screening and preservation application of quorum sensing inhibitors of Pseudomonas fluorescens and Shewanella baltica in seafood products. LWT-FOOD SCIENCE AND TECHNOLOGY, 149 (111749). [PMID:] [10.1016/j.lwt.2021.111749] |
3. Yalin Ye, Xingli Huo, Zongning Yin. (2021) Protein-protein interactions at high concentrations: Effects of ArgHCl and NaCl on the stability, viscosity and aggregation mechanisms of protein solution. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 601 (120535). [PMID:33811966] [10.1016/j.ijpharm.2021.120535] |
4. Jie Zhu, Hua Han, Faxue Li, Xueli Wang, Jianyong Yu, Chih-Chang Chu, Dequn Wu. (2019) Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 540 (634). [PMID:30690388] [10.1016/j.jcis.2018.12.091] |
1. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge. (2024) Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. SAUDI PHARMACEUTICAL JOURNAL, 32 (101934). [PMID:38223203] [10.1016/j.jsps.2023.101934] |
2. Yanbo Wang, Yongzheng Wang, Jian Chen, Shigenobu Koseki, Qing Yang, Hejun Yu, Linglin Fu. (2021) Screening and preservation application of quorum sensing inhibitors of Pseudomonas fluorescens and Shewanella baltica in seafood products. LWT-FOOD SCIENCE AND TECHNOLOGY, 149 (111749). [PMID:] [10.1016/j.lwt.2021.111749] |
3. Yalin Ye, Xingli Huo, Zongning Yin. (2021) Protein-protein interactions at high concentrations: Effects of ArgHCl and NaCl on the stability, viscosity and aggregation mechanisms of protein solution. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 601 (120535). [PMID:33811966] [10.1016/j.ijpharm.2021.120535] |
4. Jie Zhu, Hua Han, Faxue Li, Xueli Wang, Jianyong Yu, Chih-Chang Chu, Dequn Wu. (2019) Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 540 (634). [PMID:30690388] [10.1016/j.jcis.2018.12.091] |