Grouped product items

SKU

Size

Availability

Price

Qty

L274353-100g

100g

In stock

$85.90

L274353-500g

500g

In stock

$304.90

L274353-12×100g

12×100g

Available within 8-12 weeks(?)

$927.90

L274353-12×500g

12×500g

Available within 8-12 weeks(?)

$3,292.90

Basic Description

Synonyms	L-(+)-Arginine monohydrochloride \| (S)-(+)-Arginine hydrochloride \| (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride \| L-Arginine monohydrochloride
Specifications & Purity	PharmPure™, USP
Biochemical and Physiological Mechanisms	Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.
Storage Temp	Room temperature
Shipped In	Normal
Grade	PharmPure™, USP

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)

Discover Target: F2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

Discover Target: CHRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

Discover Target: HTR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD3 Tclin Dopamine D3 receptor (14368 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

Discover Target: SLC6A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

Discover Target: PDE3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

Discover Target: HTR2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)

Discover Target: TBXA2R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

Discover Target: PDE4A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

Discover Target: ADORA3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH3 Tclin Histamine H3 receptor (10389 Activities)

Discover Target: HRH3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

Discover Target: KDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride
INCHI	InChI=1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
InChi Key	KWTQSFXGGICVPE-WCCKRBBISA-N
Canonical SMILES	Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
Isomeric SMILES	C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl
WGK Germany	1
Alternate CAS	15595-35-4
PubChem CID	66250
Molecular Weight	210.66
Beilstein	6099937

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
C2416131	Certificate of Analysis	Feb 26, 2024	L274353
C2416136	Certificate of Analysis	Feb 26, 2024	L274353
L2403052	Certificate of Analysis	Feb 26, 2024	L274353
F23251568	Certificate of Analysis	Jun 02, 2023	L274353
F23251576	Certificate of Analysis	Jun 02, 2023	L274353
F23251579	Certificate of Analysis	Jun 02, 2023	L274353
F23251597	Certificate of Analysis	Jun 02, 2023	L274353

Chemical and Physical Properties

Solubility	alcohol: slightly soluble；ether: insoluble；water: freely soluble
Sensitivity	Air sensitive；Moisture sensitive
Specific Rotation[α]	23 ° (C=8, HCl(1+1))
Melt Point(°C)	226-230°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	1
Merck Index	780

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge. (2024) Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. SAUDI PHARMACEUTICAL JOURNAL, 32 (101934). [PMID:38223203] [10.1016/j.jsps.2023.101934]
2. Yanbo Wang, Yongzheng Wang, Jian Chen, Shigenobu Koseki, Qing Yang, Hejun Yu, Linglin Fu. (2021) Screening and preservation application of quorum sensing inhibitors of Pseudomonas fluorescens and Shewanella baltica in seafood products. LWT-FOOD SCIENCE AND TECHNOLOGY, 149 (111749). [PMID:] [10.1016/j.lwt.2021.111749]
3. Yalin Ye, Xingli Huo, Zongning Yin. (2021) Protein-protein interactions at high concentrations: Effects of ArgHCl and NaCl on the stability, viscosity and aggregation mechanisms of protein solution. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 601 (120535). [PMID:33811966] [10.1016/j.ijpharm.2021.120535]
4. Jie Zhu, Hua Han, Faxue Li, Xueli Wang, Jianyong Yu, Chih-Chang Chu, Dequn Wu. (2019) Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 540 (634). [PMID:30690388] [10.1016/j.jcis.2018.12.091]

References

1. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge. (2024) Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. SAUDI PHARMACEUTICAL JOURNAL, 32 (101934). [PMID:38223203] [10.1016/j.jsps.2023.101934]
2. Yanbo Wang, Yongzheng Wang, Jian Chen, Shigenobu Koseki, Qing Yang, Hejun Yu, Linglin Fu. (2021) Screening and preservation application of quorum sensing inhibitors of Pseudomonas fluorescens and Shewanella baltica in seafood products. LWT-FOOD SCIENCE AND TECHNOLOGY, 149 (111749). [PMID:] [10.1016/j.lwt.2021.111749]
3. Yalin Ye, Xingli Huo, Zongning Yin. (2021) Protein-protein interactions at high concentrations: Effects of ArgHCl and NaCl on the stability, viscosity and aggregation mechanisms of protein solution. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 601 (120535). [PMID:33811966] [10.1016/j.ijpharm.2021.120535]
4. Jie Zhu, Hua Han, Faxue Li, Xueli Wang, Jianyong Yu, Chih-Chang Chu, Dequn Wu. (2019) Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 540 (634). [PMID:30690388] [10.1016/j.jcis.2018.12.091]

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L(+)-Arginine hydrochloride - USP, high purity , CAS No.1119-34-2