L - (+) - ergothione (ET) has the highest concentration in oxidative stress tissues, and the highest concentration in blood, lens, bone marrow, semen, and liver. It is an antioxidant that prevents cell apoptosis by clearing reactive oxygen species and nit
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Note
10mg卖完停产，不再备货
Product Description
Ergothioneine is a stable antioxidant that can be found under conditions of excessive oxidative stress in plant and animal tissue. Ergothioneine can scavenge free radicals and protect cells from UV-induced ROS with higher efficiency than antioxidants coenzyme Q(10) or idebenone. The compound could be a non-toxic thiol buffering antioxidant, enhance cell viability induced by hydrogen peroxide (H2O2), and inhibit DNA oxidation by peroxynitrite (ONOO-) in the human neuronal hybridoma cell line (N-18-RE-105). An antioxidant and free radical scavenger
Application：
L - (+) - ergot sulfur is suitable for studying its reactivity with 2,2 '- and 4,4' - bipyridine disulfides (2-Py-S-S-2-Py and 4-Py-S-S-4-Py).
It can also be used for the incubation of experimental cells and for in vitro kinase activity measurement of ATM (Ataxia telangiectasia mutation) or ATR (ATM - and RAD3- related).
L - (+) - ergot has been used to:
1. As a component of the cumulus oocyte complex (COC) maturation medium, its protective effect on lipid peroxidation formation was tested;
2. As an antioxidant compound, it is used to detect type 2 diabetes patients;
3. As a positive control for soluble carrier protein 22A4 (SLC22A4) transport detection.
K2428536
