Click Here for 5% Off Your First Aladdin Purchase!

L(+)-Glutamic acid - ≥99%, high purity , CAS No.56-86-0

  • ≥99%
Item Number
G103978
Grouped product items
SKUSizeAvailabilityPrice Qty
G103978-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
G103978-100g
100g
In stock
$12.90
G103978-250g
250g
In stock
$21.90
G103978-500g
500g
In stock
$33.90

Excitatory neurotransmitter

Basic Description

SynonymsL-glutamic acid|GLUTAMIC ACID|56-86-0|L-glutamate|(2S)-2-Aminopentanedioic acid|(S)-2-Aminopentanedioic acid|Glutamidex|Glutaminol|H-Glu-OH|glutacid|Aciglut|Glutamicol|Glutaton|L-Glutaminic acid|(S)-Glutamic acid|glutaminic acid|Glusate|L-glu|Acidum gluta
Specifications & Purity≥99%
Shipped InNormal

Associated Targets

SLC1A1 Tchem Excitatory amino acid transporter 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIA4 Tclin Glutamate receptor 4 5 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIK5 Tclin Glutamate receptor ionotropic, kainate 5 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIK1 Tclin Glutamate receptor ionotropic, kainate 1 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIA2 Tclin Glutamate receptor 2 5 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIA3 Tclin Glutamate receptor 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIK2 Tclin Glutamate receptor ionotropic, kainate 2 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIK3 Tclin Glutamate receptor ionotropic, kainate 3 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM2 Tchem Metabotropic glutamate receptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM5 Tchem Metabotropic glutamate receptor 5 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM7 Tchem Metabotropic glutamate receptor 7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM8 Tchem Metabotropic glutamate receptor 8 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIA1 Tclin Glutamate receptor 1 4 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM3 Tchem Metabotropic glutamate receptor 3 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRM6 Tchem Metabotropic glutamate receptor 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488183207
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488183207
IUPAC Name (2S)-2-aminopentanedioic acid
INCHI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChi Key WHUUTDBJXJRKMK-VKHMYHEASA-N
Canonical SMILES C(CC(=O)O)C(C(=O)O)N
Isomeric SMILES C(CC(=O)O)[C@@H](C(=O)O)N
WGK Germany 1
PubChem CID 33032
Molecular Weight 147.13
Beilstein 1723801

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

49 results found

Lot NumberCertificate TypeDateItem
F2405359Certificate of AnalysisJun 17, 2024 G103978
F2405358Certificate of AnalysisJun 17, 2024 G103978
F2405360Certificate of AnalysisJun 17, 2024 G103978
F2405361Certificate of AnalysisJun 17, 2024 G103978
F2405362Certificate of AnalysisJun 17, 2024 G103978
F2405363Certificate of AnalysisJun 17, 2024 G103978
C2413026Certificate of AnalysisMar 19, 2024 G103978
C2412033Certificate of AnalysisMar 14, 2024 G103978
C2414609Certificate of AnalysisMar 01, 2024 G103978
C2421400Certificate of AnalysisMar 01, 2024 G103978
C2422205Certificate of AnalysisMar 01, 2024 G103978
C2422193Certificate of AnalysisMar 01, 2024 G103978
C2421393Certificate of AnalysisMar 01, 2024 G103978
B2401111Certificate of AnalysisFeb 18, 2024 G103978
B2401110Certificate of AnalysisFeb 18, 2024 G103978
B2401108Certificate of AnalysisFeb 18, 2024 G103978
B2401107Certificate of AnalysisFeb 18, 2024 G103978
B2401109Certificate of AnalysisFeb 02, 2024 G103978
J2320396Certificate of AnalysisOct 24, 2023 G103978
J2320397Certificate of AnalysisOct 24, 2023 G103978
J2320419Certificate of AnalysisOct 24, 2023 G103978
J2307093Certificate of AnalysisOct 13, 2023 G103978
J2307092Certificate of AnalysisOct 13, 2023 G103978
J2307091Certificate of AnalysisOct 13, 2023 G103978
J2307090Certificate of AnalysisOct 13, 2023 G103978
J2307088Certificate of AnalysisOct 13, 2023 G103978
L2325075Certificate of AnalysisOct 13, 2023 G103978
F2329154Certificate of AnalysisJul 11, 2023 G103978
F2329157Certificate of AnalysisJul 11, 2023 G103978
F2329156Certificate of AnalysisJul 11, 2023 G103978
F2329155Certificate of AnalysisJul 11, 2023 G103978
F2329182Certificate of AnalysisJul 11, 2023 G103978
D2319517Certificate of AnalysisApr 25, 2023 G103978
D2319478Certificate of AnalysisApr 25, 2023 G103978
D23191145Certificate of AnalysisApr 25, 2023 G103978
D23191231Certificate of AnalysisApr 25, 2023 G103978
D2319463Certificate of AnalysisApr 25, 2023 G103978
D2319472Certificate of AnalysisApr 25, 2023 G103978
I2224395Certificate of AnalysisSep 30, 2022 G103978
D2301005Certificate of AnalysisSep 30, 2022 G103978
I2224396Certificate of AnalysisSep 30, 2022 G103978
I2224393Certificate of AnalysisSep 30, 2022 G103978
I2224383Certificate of AnalysisSep 30, 2022 G103978
I2224382Certificate of AnalysisSep 30, 2022 G103978
B2216308Certificate of AnalysisFeb 18, 2022 G103978
B2216328Certificate of AnalysisFeb 18, 2022 G103978
B2216322Certificate of AnalysisFeb 18, 2022 G103978
B2216312Certificate of AnalysisFeb 18, 2022 G103978
B2216329Certificate of AnalysisFeb 18, 2022 G103978

more

Chemical and Physical Properties

SensitivityMoisture sensitive.
Specific Rotation[α]32 ° (C=5, HCl)
Melt Point(°C)205°C

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H314:Causes severe skin burns and eye damage

H318:Causes serious eye damage

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

WGK Germany 1
Merck Index 4469

Related Documents

References

1. Pergner J & Kozmik Z.  (2017)  Amphioxus photoreceptors - insights into the evolution of vertebrate opsins, vision and circadian rhythmicity..  Int J Dev Biol,  61  (10-11-12): (665-681).  [PMID:29319115]
2. Cheng K et al..  (2019)  Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome..  Front Neurosci,  13  (1098).  [PMID:31680833]
3. Hu C et al..  (2022)  Different Aberrant Changes of mGluR5 and Its Downstream Signaling Pathways in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents..  Front Cell Dev Biol,  10  (844378).  [PMID:35646890]
4. Francescone R et al..  (2021)  Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression..  Cancer Discov,  11  (2): (446-479).  [PMID:33127842]
5. Mukherjee C et al..  (2020)  Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain..  Cell Metab,  32  (2): (259-272.e10).  [PMID:32531201]
6. Guo C et al..  (2021)  Purkinje cell outputs selectively inhibit a subset of unipolar brush cells in the input layer of the cerebellar cortex..  Elife,  10    [PMID:34369877]
7. Wang C et al..  (2022)  The neuroprotective effect of melatonin in glutamate excitotoxicity of R28 cells and mouse retinal ganglion cells..  Front Endocrinol (Lausanne),  13  (986131).  [PMID:36313740]
8. Boudker O, Ryan RM, Yernool D, Shimamoto K, Gouaux E.  (2007)  Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter..  Nature,  445  (7126): (387-93).  [PMID:17230192]
9. Meyerson JR, Kumar J, Chittori S, Rao P, Pierson J, Bartesaghi A, Mayer ML, Subramaniam S.  (2014)  Structural mechanism of glutamate receptor activation and desensitization..  Nature,  514  (7522): (328-34).  [PMID:25119039]
10. He S et al..  (2014)  Cholinergic modulation of large-conductance calcium-activated potassium channels regulates synaptic strength and spine calcium in cartwheel cells of the dorsal cochlear nucleus..  J Neurosci,  34  (15): (5261-72).  [PMID:24719104]
11. Perez-Rosello T et al..  (2013)  Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis..  J Neurosci,  33  (22): (9259-72).  [PMID:23719795]
12. H Kazemi,B Hoop.  (1991-01-01)  Glutamic acid and gamma-aminobutyric acid neurotransmitters in central control of breathing..  Journal of applied physiology (Bethesda, Md. : 1985),  70  ((1)): (1-7).  [PMID:1672687]
13. N M van Gelder.  (1990-01-01)  Neuronal discharge hypersynchrony and the intracranial water balance in relation to glutamic acid and taurine redistribution: migraine and epilepsy..  Progress in clinical and biological research,  351  (1-20).  [PMID:1978346]
14. .  (1985-04-01)  Intestinal ornithine synthesis from glutamic acid..  Nutrition reviews,  43  ((4)): (119-121).  [PMID:2860626]
15. D Rating,H Siemes,W Löscher.  (1983-01-01)  Low CSF GABA concentration in children with febrile convulsions, untreated epilepsy, and meningitis..  Journal of neurology,  230  ((4)): (217-225).  [PMID:6198481]
16. S Ishiwata,K Itoh,T Yamaguchi,N Ishida,M Mizugaki.  (1995-05-01)  Comparison of serum and urinary levels of modified nucleoside, 1-methyladenosine, in cancer patients using a monoclonal antibody-based inhibition ELISA..  The Tohoku journal of experimental medicine,  176  ((1)): (61-68).  [PMID:7482520]
17. G Grasselli,L Viganò,G Capri,A Locatelli,E Tarenzi,C Spreafico,A Bertuzzi,A Giani,C Materazzo,S Cresta,A Perotti,P Valagussa,L Gianni.  (2001-04-17)  Clinical and pharmacologic study of the epirubicin and paclitaxel combination in women with metastatic breast cancer..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology,  19  ((8)): (2222-2231).  [PMID:11304775]
18. C J L Silwood,E Lynch,A W D Claxson,M C Grootveld.  (2002-07-05)  1H and (13)C NMR spectroscopic analysis of human saliva..  Journal of dental research,  81  ((6)): (422-427).  [PMID:12097436]
19. C W Noorlander,P N E de Graan,P G J Nikkels,L H Schrama,G H A Visser.  (2004-05-12)  Distribution of glutamate transporters in the human placenta..  Placenta,  25  ((6)): (489-495).  [PMID:15135231]
20. Anders A Jensen,Thomas Christesen,Ulrik Bølcho,Jeremy R Greenwood,Giovanna Postorino,Stine B Vogensen,Tommy N Johansen,Jan Egebjerg,Hans Bräuner-Osborne,Rasmus P Clausen.  (2007-08-04)  Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA..  Journal of medicinal chemistry,  50  ((17)): (4177-4185).  [PMID:17672447]
21. Shinsaku Nakagawa.  (2008-11-05)  [Efficacy and safety of poly (gamma-glutamic acid) based nanoparticles (gamma-PGA NPs) as vaccine carrier]..  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,  128  ((11)): (1559-1565).  [PMID:18981690]
22. Kevin Guo,Liang Li.  (2009-03-25)  Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome..  Analytical chemistry,  81  ((10)): (3919-3932).  [PMID:19309105]
23. James J Fleming,Pamela M England.  (2010-01-26)  Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands..  Bioorganic & medicinal chemistry,  18  ((4)): (1381-1387).  [PMID:20096591]
24. Seok-Min Kang,Jong-Chul Park,Min-Jeong Shin,Hyeran Lee,Jaewon Oh,Do Hyun Ryu,Geum-Sook Hwang,Ji Hyung Chung.  (2010-12-21)  ¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure..  Clinical biochemistry,  44  ((4)): (293-299).  [PMID:21167146]
25. Reşit Çakmak,Serdar Durdagi,Deniz Ekinci,Murat Sentürk,Giray Topal.  (2011-07-29)  Design, synthesis and biological evaluation of novel nitroaromatic compounds as potent glutathione reductase inhibitors..  Bioorganic & medicinal chemistry letters,  21  ((18)): (5398-5402).  [PMID:21795044]
26. Sascha Dietrich,Jennifer Hüllein,Michael Hundemer,Nicola Lehners,Alexander Jethwa,David Capper,Till Acker,Boyan K Garvalov,Mindaugas Andrulis,Carolin Blume,Christoph Schulte,Thomas Mandel,Julia Meissner,Stefan Fröhling,Christof von Kalle,Hanno Glimm,Anthony D Ho,Thorsten Zenz.  (2013-05-22)  Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology,  31  ((19)): (e300-e303).  [PMID:23690412]
27. Sabine Ruehle,Floor Remmers,Hector Romo-Parra,Federico Massa,Melanie Wickert,Simone Wörtge,Martin Häring,Nadine Kaiser,Giovanni Marsicano,Hans-Christian Pape,Beat Lutz.  (2013-06-21)  Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((25)): (10264-10277).  [PMID:23785142]
28. P M Viral,C Nagarathna,B S Shakuntala.  (2013-07-17)  Chemomechanical caries removal in primary molars : evaluation of marginal leakage and shear bond strength in bonded restorations--an in vitro study..  The Journal of clinical pediatric dentistry,  37  ((3)): (269-274).  [PMID:23855171]
29. Lu Qi,Qibin Qi,Sabrina Prudente,Christine Mendonca,Francesco Andreozzi,Natalia di Pietro,Mariella Sturma,Valeria Novelli,Gaia Chiara Mannino,Gloria Formoso,Ernest V Gervino,Thomas H Hauser,Jochen D Muehlschlegel,Monika A Niewczas,Andrzej S Krolewski,Gianni Biolo,Assunta Pandolfi,Eric Rimm,Giorgio Sesti,Vincenzo Trischitta,Frank Hu,Alessandro Doria.  (2013-08-29)  Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes..  JAMA,  310  ((8)): (821-828).  [PMID:23982368]
30. E Yildiz,E Sirinkaraarslan,Z Yegin,M A Cebe,G Tosun.  (2013-12-04)  Effect of caries removal techniques on the bond strength of adhesives to caries-affected primary dentin in vitro..  European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry,  14  ((3)): (209-214).  [PMID:24295006]
31. Ryan E Tooker,Mikhail Y Lipin,Valerie Leuranguer,Eva Rozsa,Jayne R Bramley,Jacqueline L Harding,Melissa M Reynolds,Jozsef Vigh.  (2013-12-07)  Nitric oxide mediates activity-dependent plasticity of retinal bipolar cell output via S-nitrosylation..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((49)): (19176-19193).  [PMID:24305814]
32. Kohichi Tanaka.  (2013-12-18)  [Role of glutamate transporters in the pathophysiology of major mental illnesses]..  Nihon yakurigaku zasshi. Folia pharmacologica Japonica,  142  ((6)): (291-296).  [PMID:24334928]
33. Kjell Heuser,Karolina Szokol,Erik Taubøll.  (2014-01-17)  The role of glial cells in epilepsy..  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,  134  ((1)): (37-41).  [PMID:24429754]
34. Nils Muhlert,Matteo Atzori,Enrico De Vita,David L Thomas,Rebecca S Samson,Claudia A M Wheeler-Kingshott,Jeroen J G Geurts,David H Miller,Alan J Thompson,Olga Ciccarelli.  (2014-01-17)  Memory in multiple sclerosis is linked to glutamate concentration in grey matter regions..  Journal of neurology, neurosurgery, and psychiatry,  85  ((8)): (833-839).  [PMID:24431465]
35. Yumi Hayashi,Ryoji Tsurumizu,Jun Tsukahara,Kazuki Takeda,Shin-ichiro Narita,Makiko Mori,Kunio Miki,Hajime Tokuda.  (2014-02-27)  Roles of the protruding loop of factor B essential for the localization of lipoproteins (LolB) in the anchoring of bacterial triacylated proteins to the outer membrane..  The Journal of biological chemistry,  289  ((15)): (10530-10539).  [PMID:24569999]
36. Zoltán Ivics,Wiebke Garrels,Lajos Mátés,Tien Yin Yau,Sanum Bashir,Vaclav Zidek,Vladimír Landa,Aron Geurts,Michal Pravenec,Thomas Rülicke,Wilfried A Kues,Zsuzsanna Izsvák.  (2014-03-15)  Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons..  Nature protocols,  ((4)): (810-827).  [PMID:24625780]
37. Minhajuddin Sirajuddin,Luke M Rice,Ronald D Vale.  (2014-03-19)  Regulation of microtubule motors by tubulin isotypes and post-translational modifications..  Nature cell biology,  16  ((4)): (335-344).  [PMID:24633327]
38. Elie Dolgin.  (2014-04-04)  Therapeutics: Negative feedback..  Nature,  508  ((7494)): (S10-S11).  [PMID:24695327]
39. Mayumi Yamada,Yusuke Seto,Shinichiro Taya,Tomoo Owa,Yukiko U Inoue,Takayoshi Inoue,Yoshiya Kawaguchi,Yo-Ichi Nabeshima,Mikio Hoshino.  (2014-04-04)  Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  34  ((14)): (4786-4800).  [PMID:24695699]
40. Joshua D Bell,Theresa Currier Thomas,Elliot Lass,Jinglu Ai,Hoyee Wan,Jonathan Lifshitz,Andrew J Baker,R Loch Macdonald.  (2014-04-22)  Platelet-mediated changes to neuronal glutamate receptor expression at sites of microthrombosis following experimental subarachnoid hemorrhage..  Journal of neurosurgery,  121  ((6)): (1424-1431).  [PMID:24745710]
41. Anna Grygoruk,Audrey Chen,Ciara A Martin,Hakeem O Lawal,Hao Fei,Gabriel Gutierrez,Traci Biedermann,Rod Najibi,Richard Hadi,Amit K Chouhan,Niall P Murphy,Felix E Schweizer,Gregory T Macleod,Nigel T Maidment,David E Krantz.  (2014-05-16)  The redistribution of Drosophila vesicular monoamine transporter mutants from synaptic vesicles to large dense-core vesicles impairs amine-dependent behaviors..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  34  ((20)): (6924-6937).  [PMID:24828646]
42. Yang-Kai Wang,Du Shen,Qiang Hao,Qiang Yu,Zhao-Tang Wu,Yu Deng,Yan-Fang Chen,Wen-Jun Yuan,Qi-Kuan Hu,Ding-Feng Su,Wei-Zhong Wang.  (2014-05-20)  Overexpression of angiotensin-converting enzyme 2 attenuates tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive rats..  American journal of physiology. Heart and circulatory physiology,  307  ((2)): (H182-H190).  [PMID:24838502]
43. Hiromi Yoshida,Akihide Yoshihara,Misa Teraoka,Yuji Terami,Goro Takata,Ken Izumori,Shigehiro Kamitori.  (2014-05-23)  X-ray structure of a novel L-ribose isomerase acting on a non-natural sugar L-ribose as its ideal substrate..  The FEBS journal,  281  ((14)): (3150-3164).  [PMID:24846739]
44. Mette H Poulsen,Jacob Andersen,Rune Christensen,Kasper B Hansen,Stephen F Traynelis,Kristian Strømgaard,Anders Skov Kristensen.  (2014-05-28)  Binding of ArgTX-636 in the NMDA receptor ion channel..  Journal of molecular biology,  427  ((1)): (176-189).  [PMID:24862283]
45. Ali Alhoshani,Rosemarie Vithayathil,Jonathan Bandong,Katherine M Chrunyk,Gabriel O Moreno,Gregory A Weiss,Melanie J Cocco.  (2014-05-28)  Glutamate provides a key structural contact between reticulon-4 (Nogo-66) and phosphocholine..  Biochimica et biophysica acta,  1838  ((9)): (2350-2356).  [PMID:24863057]
46. Flávio Afonso Gonçalves Mourão,Hércules Ribeiro Leite,Luciana Estefani Drumond de Carvalho,Talita Hélen Ferreira E Vieira,Mauro Cunha Xavier Pinto,Daniel de Castro Medeiros,Ian Lara Lamounier Andrade,Daniela Fontes Gonçalves,Grace Schenatto Pereira,Márcio Flávio Dutra Moraes,André Ricardo Massensini.  (2014-06-07)  Neuroprotective effect of exercise in rat hippocampal slices submitted to in vitro ischemia is promoted by decrease of glutamate release and pro-apoptotic markers..  Journal of neurochemistry,  131  ((1)): (65-73).  [PMID:24903976]
47. Yuanyuan Chen,Hong Tang,William Seibel,Ruben Papoian,Ki Oh,Xiaoyu Li,Jianye Zhang,Marcin Golczak,Krzysztof Palczewski,Philip D Kiser.  (2014-06-11)  Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase..  Molecular pharmacology,  86  ((2)): (231-242).  [PMID:24913940]
48. Wilson I Gonsalves,Michelle R Mahoney,Daniel J Sargent,Garth D Nelson,Steven R Alberts,Frank A Sinicrope,Richard M Goldberg,Paul J Limburg,Stephen N Thibodeau,Axel Grothey,Joleen M Hubbard,Emily Chan,Suresh Nair,Jeffrey L Berenberg,Robert R McWilliams.  (2014-06-14)  Patient and tumor characteristics and BRAF and KRAS mutations in colon cancer, NCCTG/Alliance N0147..  Journal of the National Cancer Institute,  106  ((7)): (doi:10-doi:10).  [PMID:24925349]
49. Hongying Wei,Furong Deng,Yiyong Chen,Yu Qin,Yu Hao,Xinbiao Guo.  (2014-06-17)  Ultrafine carbon black induces glutamate and ATP release by activating connexin and pannexin hemichannels in cultured astrocytes..  Toxicology,  323  (32-41).  [PMID:24932759]
50. Helen N Saada,Ussama Z Said,Elsayed M E Mahdy,Hattem E Elmezayen,Shereen M Shedid.  (2014-06-18)  Fish oil omega-3 fatty acids reduce the severity of radiation-induced oxidative stress in the rat brain..  International journal of radiation biology,  90  ((12)): (1179-1183).  [PMID:24937371]
51. Hirotoshi Morishita,Daisuke Kurita,Kunishige Kataoka,Takeshi Sakurai.  (2014-06-22)  Study on dioxygen reduction by mutational modifications of the hydrogen bond network leading from bulk water to the trinuclear copper center in bilirubin oxidase..  Biochemical and biophysical research communications,  450  ((1)): (767-772).  [PMID:24952160]
52. Isaac Marin-Valencia,M Ali Hooshyar,Kumar Pichumani,A Dean Sherry,Craig R Malloy.  (2014-09-19)  The ratio of acetate-to-glucose oxidation in astrocytes from a single 13C NMR spectrum of cerebral cortex..  Journal of neurochemistry,  132  ((1)): (99-109).  [PMID:25231025]
53. Heidi Turkia,Heli Sirén,Merja Penttilä,Juha-Pekka Pitkänen.  (2014-10-05)  Capillary electrophoresis with laser-induced fluorescence detection for studying amino acid uptake by yeast during beer fermentation..  Talanta,  131  (366-371).  [PMID:25281116]
54. Margarita V Glazova,Liubov S Nikitina,Kirill A Hudik,Olga D Kirillova,Nadezhda A Dorofeeva,Anatoly A Korotkov,Elena V Chernigovskaya.  (2014-10-30)  Inhibition of ERK1/2 signaling prevents epileptiform behavior in rats prone to audiogenic seizures..  Journal of neurochemistry,  132  ((2)): (218-229).  [PMID:25351927]
55. Daniel R Dempsey,Kristen A Jeffries,Jason D Bond,Anne-Marie Carpenter,Santiago Rodriguez-Ospina,Leonid Breydo,K Kenneth Caswell,David J Merkler.  (2014-11-19)  Mechanistic and structural analysis of Drosophila melanogaster arylalkylamine N-acetyltransferases..  Biochemistry,  53  ((49)): (7777-7793).  [PMID:25406072]
56. Frederic J Kaye,Alison M Ivey,Walter E Drane,William M Mendenhall,Robert W Allan.  (2014-12-06)  Clinical and radiographic response with combined BRAF-targeted therapy in stage 4 ameloblastoma..  Journal of the National Cancer Institute,  107  ((1)): (378-378).  [PMID:25475564]
57. Wangfa Zhao,Shih-Chieh Chuang,Steven R Young,Riccardo Bianchi,Robert K S Wong.  (2015-01-09)  Extracellular glutamate exposure facilitates group I mGluR-mediated epileptogenesis in the hippocampus..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  35  ((1)): (308-315).  [PMID:25568123]
58. Luiz G B Michelini,Tiago R Figueira,Edilene S Siqueira-Santos,Roger F Castilho.  (2015-01-18)  Rotenone exerts similar stimulatory effects on H2O2 production by isolated brain mitochondria from young-adult and old rats..  Neuroscience letters,  589  (25-30).  [PMID:25596437]
59. Adam E Locke,Bratati Kahali,Sonja I Berndt,Anne E Justice,Tune H Pers,Felix R Day,Corey Powell,Sailaja Vedantam,Martin L Buchkovich,Jian Yang,Damien C Croteau-Chonka,Tonu Esko,Tove Fall,Teresa Ferreira,Stefan Gustafsson,Zoltán Kutalik', "Jian'an Luan", 'Reedik Mägi,Joshua C Randall,Thomas W Winkler,Andrew R Wood,Tsegaselassie Workalemahu,Jessica D Faul,Jennifer A Smith,Jing Hua Zhao,Wei Zhao,Jin Chen,Rudolf Fehrmann,Åsa K Hedman,Juha Karjalainen,Ellen M Schmidt,Devin Absher,Najaf Amin,Denise Anderson,Marian Beekman,Jennifer L Bolton,Jennifer L Bragg-Gresham,Steven Buyske,Ayse Demirkan,Guohong Deng,Georg B Ehret,Bjarke Feenstra,Mary F Feitosa,Krista Fischer,Anuj Goel,Jian Gong,Anne U Jackson,Stavroula Kanoni,Marcus E Kleber,Kati Kristiansson,Unhee Lim,Vaneet Lotay,Massimo Mangino,Irene Mateo Leach,Carolina Medina-Gomez,Sarah E Medland,Michael A Nalls,Cameron D Palmer,Dorota Pasko,Sonali Pechlivanis,Marjolein J Peters,Inga Prokopenko,Dmitry Shungin,Alena Stančáková,Rona J Strawbridge,Yun Ju Sung,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sander W van der Laan,Jessica van Setten,Jana V Van Vliet-Ostaptchouk,Zhaoming Wang,Loïc Yengo,Weihua Zhang,Aaron Is.  (2015-02-13)  Genetic studies of body mass index yield new insights for obesity biology..  Nature,  518  ((7538)): (197-206).  [PMID:25673413]
60. Hao Bin Wu,Bao Yu Xia,Le Yu,Xin-Yao Yu,Xiong Wen David Lou.  (2015-03-12)  Porous molybdenum carbide nano-octahedrons synthesized via confined carburization in metal-organic frameworks for efficient hydrogen production..  Nature communications,  (6512-6512).  [PMID:25758159]
61. Nuno R Ferreira,C F Lourenço,Rui M Barbosa,João Laranjinha.  (2015-03-19)  Coupling of ascorbate and nitric oxide dynamics in vivo in the rat hippocampus upon glutamatergic neuronal stimulation: a novel functional interplay..  Brain research bulletin,  114  (13-19).  [PMID:25783673]
62. Ming Li,Fenghe Niu,Xilin Zhu,Xiaopan Wu,Ning Shen,Xiaozhong Peng,Ying Liu.  (2015-04-29)  PRRT2 Mutant Leads to Dysfunction of Glutamate Signaling..  International journal of molecular sciences,  16  ((5)): (9134-9151).  [PMID:25915028]
63. Yasuo Watanabe,Kohki Kawata,Seiya Watanabe.  (2015-04-29)  Monitoring Technology for Gamma-Aminobutyric acid Production in Polished Mochi Barley Grains using a Carbon Dioxide Sensor..  Journal of food science,  80  ((6)): (H1418-H1424).  [PMID:25916326]
64. Soner Donmez,Fatma Arslan,Halit Arslan.  (2015-05-08)  A Nucleic Acid Biosensor for Detection of Hepatitis C Virus Genotype 1a Using Poly(L-Glutamic Acid)-Modified Electrode..  Applied biochemistry and biotechnology,  176  ((5)): (1431-1444).  [PMID:25947619]
65. Hayato Hikita,Takahiro Kodama,Satoshi Tanaka,Yoshinobu Saito,Yasutoshi Nozaki,Tasuku Nakabori,Satoshi Shimizu,Yoshito Hayashi,Wei Li,Minoru Shigekawa,Ryotaro Sakamori,Takuya Miyagi,Naoki Hiramatsu,Tomohide Tatsumi,Tetsuo Takehara.  (2015-06-04)  Activation of the Mitochondrial Apoptotic Pathway Produces Reactive Oxygen Species and Oxidative Damage in Hepatocytes That Contribute to Liver Tumorigenesis..  Cancer prevention research (Philadelphia, Pa.),  ((8)): (693-701).  [PMID:26038117]
66. C Plesa,N van Loo,C Dekker.  (2015-07-25)  DNA nanopore translocation in glutamate solutions..  Nanoscale,  ((32)): (13605-13609).  [PMID:26206066]
67. Melissa Malvaez,Venuz Y Greenfield,Alice S Wang,Allison M Yorita,Lili Feng,Kay E Linker,Harold G Monbouquette,Kate M Wassum.  (2015-07-28)  Basolateral amygdala rapid glutamate release encodes an outcome-specific representation vital for reward-predictive cues to selectively invigorate reward-seeking actions..  Scientific reports,  (12511-12511).  [PMID:26212790]
68. Shu-ichi Nakano,Yuichi Kitagawa,Daisuke Miyoshi,Naoki Sugimoto.  (2015-07-30)  Effects of background anionic compounds on the activity of the hammerhead ribozyme in Mg(2+)-unsaturated solutions..  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry,  20  ((6)): (1049-1058).  [PMID:26220274]
69. Hanna Österman,Isa Lindgren,Tom Lindström,Jordi Altimiras.  (2015-10-02)  Chronic hypoxia during development does not trigger pathologic remodeling of the chicken embryonic heart but reduces cardiomyocyte number..  American journal of physiology. Regulatory, integrative and comparative physiology,  309  ((10)): (R1204-R1214).  [PMID:26423711]
70. Fabian Istel,Tobias Schwarzmüller,Michael Tscherner,Karl Kuchler.  (2015-07-20)  Large-scale Phenotypic Profiling of Gene Deletion Mutants in Candida glabrata..  Bio-protocol,  ((14)):   [PMID:27774498]
71. Juliane C Campos,Bruno B Queliconi,Luiz H M Bozi,Luiz R G Bechara,Paulo M M Dourado,Allen M Andres,Paulo R Jannig,Kátia M S Gomes,Vanessa O Zambelli,Cibele Rocha-Resende,Silvia Guatimosim,Patricia C Brum,Daria Mochly-Rosen,Roberta A Gottlieb,Alicia J Kowaltowski,Julio C B Ferreira.  (2017-06-10)  Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure..  Autophagy,  13  ((8)): (1304-1317).  [PMID:28598232]
72. Christoph B Messner,Paul C Driscoll,Gabriel Piedrafita,Michael F L De Volder,Markus Ralser.  (2017-06-28)  Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice..  Proceedings of the National Academy of Sciences of the United States of America,  114  ((28)): (7403-7407).  [PMID:28652321]
73. Rachael M Giersch,Gregory C Finnigan.  (2017-10-31)  Method for Multiplexing CRISPR/Cas9 in Saccharomyces cerevisiae Using Artificial Target DNA Sequences..  Bio-protocol,  ((18)):   [PMID:29082289]
74. Aleksandra Agapova,Agnese Serafini,Michael Petridis,Debbie M Hunt,Acely Garza-Garcia,Charles D Sohaskey,Luiz Pedro Sório de Carvalho.  (2019-02-01)  Flexible nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis..  eLife,    [PMID:30702426]
75. Arif Yurdagul,Manikandan Subramanian,Xiaobo Wang,Scott B Crown,Olga R Ilkayeva,Lancia Darville,Gopi K Kolluru,Christina C Rymond,Brennan D Gerlach,Ze Zheng,George Kuriakose,Christopher G Kevil,John M Koomen,John L Cleveland,Deborah M Muoio,Ira Tabas.  (2020-02-01)  Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury..  Cell metabolism,  31  ((3)): (518-533).  [PMID:32004476]
76. Alyssa N Coyne,Benjamin L Zaepfel,Lindsey Hayes,Boris Fitchman,Yuval Salzberg,En-Ching Luo,Kelly Bowen,Hannah Trost,Stefan Aigner,Frank Rigo,Gene W Yeo,Amnon Harel,Clive N Svendsen,Dhruv Sareen,Jeffrey D Rothstein.  (2020-07-17)  G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD..  Neuron,  107  ((6)): (1124-1140).  [PMID:32673563]
77. Tetsuya Hori,JingHui Cao,Kohei Nishimura,Mariko Ariyoshi,Yasuhiro Arimura,Hitoshi Kurumizaka,Tatsuo Fukagawa.  (2020-11-19)  Essentiality of CENP-A Depends on Its Binding Mode to HJURP..  Cell reports,  33  ((7)): (108388-108388).  [PMID:33207191]
78. Ewelina Magdalena Bartoszek,Anna Maria Ostenrath,Suresh Kumar Jetti,Bram Serneels,Aytac Kadir Mutlu,Khac Thanh Phong Chau,Emre Yaksi.  (2021-08-21)  Ongoing habenular activity is driven by forebrain networks and modulated by olfactory stimuli..  Current biology : CB,  31  ((17)): (3861-3874).  [PMID:34416179]
79. Tomoyuki Mashimo,Kumar Pichumani,Vamsidhara Vemireddy,Kimmo J Hatanpaa,Dinesh Kumar Singh,Shyam Sirasanagandla,Suraj Nannepaga,Sara G Piccirillo,Zoltan Kovacs,Chan Foong,Zhiguang Huang,Samuel Barnett,Bruce E Mickey,Ralph J DeBerardinis,Benjamin P Tu,Elizabeth A Maher,Robert M Bachoo.  (2014-12-20)  Acetate is a bioenergetic substrate for human glioblastoma and brain metastases..  Cell,  159  ((7)): (1603-1614).  [PMID:25525878]
80. Fang Dong,Dan Deng,Heng Chen,Wei Cheng,Qifu Li,Rong Luo,Shijia Ding.  (2015-04-11)  Serum metabolomics study of polycystic ovary syndrome based on UPLC-QTOF-MS coupled with a pattern recognition approach..  Analytical and bioanalytical chemistry,  407  ((16)): (4683-4695).  [PMID:25860656]
81. Maarten E Witte,Adrian-Minh Schumacher,Christoph F Mahler,Jan P Bewersdorf,Jonas Lehmitz,Alexander Scheiter,Paula Sánchez,Philip R Williams,Oliver Griesbeck,Ronald Naumann,Thomas Misgeld,Martin Kerschensteiner.  (2019-01-29)  Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis..  Neuron,  101  ((4)): (615-624).  [PMID:30686733]
82. Junhua Yang,Maria Del Carmen Vitery,Jianan Chen,James Osei-Owusu,Jiachen Chu,Zhaozhu Qiu.  (2019-04-16)  Glutamate-Releasing SWELL1 Channel in Astrocytes Modulates Synaptic Transmission and Promotes Brain Damage in Stroke..  Neuron,  102  ((4)): (813-827).  [PMID:30982627]
83. Céline D Dürst,J Simon Wiegert,Nordine Helassa,Silke Kerruth,Catherine Coates,Christian Schulze,Michael A Geeves,Katalin Török,Thomas G Oertner.  (2019-04-17)  High-speed imaging of glutamate release with genetically encoded sensors..  Nature protocols,  14  ((5)): (1401-1424).  [PMID:30988508]
84. Alice E Adriaenssens,Emma K Biggs,Tamana Darwish,John Tadross,Tanmay Sukthankar,Milind Girish,Joseph Polex-Wolf,Brain Y Lam,Ilona Zvetkova,Warren Pan,Davide Chiarugi,Giles S H Yeo,Clemence Blouet,Fiona M Gribble,Frank Reimann.  (2019-08-27)  Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake..  Cell metabolism,  30  ((5)): (987-996).  [PMID:31447324]
85. Rekha Tripathi,Tanya Aggarwal,Robert Fredriksson.  (2021-05-25)  SLC38A10 Transporter Plays a Role in Cell Survival Under Oxidative Stress and Glutamate Toxicity..  Frontiers in molecular biosciences,  (671865-671865).  [PMID:34026845]

Solution Calculators