Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | L-glutamic acid | GLUTAMIC ACID | 56-86-0 | L-glutamate | (2S)-2-Aminopentanedioic acid | (S)-2-Aminopentanedioic acid | Glutamidex | Glutaminol | H-Glu-OH | glutacid | Aciglut | Glutamicol | Glutaton | L-Glutaminic acid | (S)-Glutamic acid | glutaminic acid | Glusate | L-glu | Acidum gluta |
|---|---|
| Specifications & Purity | 10mM in Water |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
Associated Targets(Human)
SLC1A1 Tchem Excitatory amino acid transporter 3 1 Activities
GRIA4 Tclin Glutamate receptor 4 5 Activities
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GRIK5 Tclin Glutamate receptor ionotropic, kainate 5 3 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GRIK1 Tclin Glutamate receptor ionotropic, kainate 1 2 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GRIA2 Tclin Glutamate receptor 2 5 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GRIA3 Tclin Glutamate receptor 3 1 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRIK2 Tclin Glutamate receptor ionotropic, kainate 2 2 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRIK3 Tclin Glutamate receptor ionotropic, kainate 3 2 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GRM2 Tchem Metabotropic glutamate receptor 2 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRM5 Tchem Metabotropic glutamate receptor 5 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRM7 Tchem Metabotropic glutamate receptor 7 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRM8 Tchem Metabotropic glutamate receptor 8 1 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRIA1 Tclin Glutamate receptor 1 4 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRM3 Tchem Metabotropic glutamate receptor 3 2 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GRM6 Tchem Metabotropic glutamate receptor 6 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Thrombin 11687 Activities
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|---|
Carbonic anhydrase II 17698 Activities
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|---|
Estrogen receptor alpha 17718 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Progesterone receptor 8562 Activities
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|---|
Beta-2 adrenergic receptor 11824 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Muscarinic acetylcholine receptor M2 10671 Activities
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|---|
Serotonin 1a (5-HT1a) receptor 14969 Activities
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|---|
Alpha-2a adrenergic receptor 9450 Activities
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Androgen Receptor 11781 Activities
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Muscarinic acetylcholine receptor M1 12690 Activities
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Monoamine oxidase A 11911 Activities
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|---|
Dopamine D1 receptor 9720 Activities
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|---|
Acetylcholinesterase 18204 Activities
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|---|
Cyclooxygenase-1 9233 Activities
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|---|
Norepinephrine transporter 10102 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Serotonin 2c (5-HT2c) receptor 11471 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Serotonin transporter 12625 Activities
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Alpha-1a adrenergic receptor 8359 Activities
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Mu opioid receptor 19785 Activities
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Dopamine D3 receptor 14368 Activities
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Dopamine transporter 10535 Activities
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HERG 29587 Activities
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Phosphodiesterase 3A 3309 Activities
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Glutamate carboxypeptidase II 711 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Serotonin 2b (5-HT2b) receptor 10323 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Thromboxane A2 receptor 5717 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Phosphodiesterase 4A 1943 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Adenosine A3 receptor 15931 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Metabotropic glutamate receptor 3 732 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Carbonic anhydrase I 13240 Activities
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Choline acetylase 63 Activities
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Histamine H3 receptor 10389 Activities
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Glutamate receptor ionotropic, AMPA 3 127 Activities
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Vascular endothelial growth factor receptor 2 20924 Activities
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Metabotropic glutamate receptor 4 2320 Activities
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Metabotropic glutamate receptor 6 361 Activities
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Glutamate receptor ionotropic, AMPA 1 277 Activities
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Glutamate receptor ionotropic, AMPA 2 847 Activities
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Glutamate receptor ionotropic kainate 3 50 Activities
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Metabotropic glutamate receptor 1 2309 Activities
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Metabotropic glutamate receptor 5 5733 Activities
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Cytochrome P450 2D6 33882 Activities
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Excitatory amino acid transporter 3 527 Activities
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Excitatory amino acid transporter 1 586 Activities
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Glutamate receptor ionotropic kainate 5 45 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ATP-citrate synthase 168 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Glutamate receptor ionotropic kainate 1 340 Activities
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Cytochrome P450 1A2 26471 Activities
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Glutathione reductase 335 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 36611 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Tetanus toxin 50 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Renal sodium-dependent phosphate transport protein 1 33 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Metabotropic glutamate receptor 2 1326 Activities
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Metabotropic glutamate receptor 8 169 Activities
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Histone deacetylase 6 222 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Glutamate receptor ionotropic, AMPA 4 112 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Glutamate receptor ionotropic kainate 2 298 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Excitatory amino acid transporter 2 39 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Metabotropic glutamate receptor 7 580 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Glutamate racemase 2 Activities
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Dihydrodipicolinate synthase 65 Activities
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|---|
Canis familiaris 36305 Activities
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Rattus norvegicus 775804 Activities
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CHO 4503 Activities
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|---|
Excitatory amino acid transporter 4 71 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Replicase polyprotein 1ab 378 Activities
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Thioredoxin reductase 1, cytoplasmic 45279 Activities
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Plasma 328 Activities
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|---|
4'-phosphopantetheinyl transferase ffp 24982 Activities
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Glutamate NMDA receptor 6467 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Monocarboxylate transporter 10 73 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Glutamate receptor ionotropic, AMPA 2103 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Glutamate receptor ionotropic, kainate 722 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Glutamate NMDA receptor; Grin1/Grin2b 1028 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Glutamate receptors; NMDA/AMPA 104 Activities
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Glutamate NMDA receptor; Grin1/Grin2a 798 Activities
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Glutamate NMDA receptor; Grin1/Grin2c 1127 Activities
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|---|
Vicia faba 57 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
General amino-acid permease GAP1 481 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Glutamate receptor AMPA 1/2 4 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Carbonic anhydrase-like protein, putative 25 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SARS-CoV-2 38078 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Prolyl 4-hydroxylase 72 Activities
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Names and Identifiers
| IUPAC Name | (2S)-2-aminopentanedioic acid |
|---|---|
| INCHI | InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1 |
| InChi Key | WHUUTDBJXJRKMK-VKHMYHEASA-N |
| Canonical SMILES | C(CC(=O)O)C(C(=O)O)N |
| Isomeric SMILES | C(CC(=O)O)[C@@H](C(=O)O)N |
| WGK Germany | 1 |
| PubChem CID | 33032 |
| Molecular Weight | 147.13 |
| Beilstein | 1723801 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | Moisture sensitive. |
|---|---|
| Specific Rotation[α] | 32 ° (C=5, HCl) |
| Melt Point(°C) | 205°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS05 |
|---|---|
| Signal | Danger |
| Hazard Statements | H314:Causes severe skin burns and eye damage H318:Causes serious eye damage |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
| WGK Germany | 1 |
| Merck Index | 4469 |
Related Documents
FAQs and Articles
Citations of This Product
| 1. Ting Gong, Qi Mu, Yongjian Xu, Weiyong Wang, Lijie Meng, Xianzhou Feng, Wenjiao Liu, Zheng Ao, Yiyu Zhang, Xiang Chen, Houqiang Xu. (2023) Expression of the umami taste receptor T1R1/T1R3 in porcine testis of: function in regulating testosterone synthesis and autophagy in Leydig cells. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, (11): (106429). [PMID:38035949] |
| 2. Jierui Yang, Huiting Qiu, Shuang Meng, Yunhui Yang. (2024) A sensing platform for ascorbic acid based on the spatial confinement of covalent organic frameworks. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 308 (19): (123687). [PMID:38042123] |
| 3. Xin Huang, Qiufen Wang, Shouxiang Jiang, Bin Wang, Wenjun Xie, Chengfei Wang, Haoran Li, Guan Wang, Gengxiu Zheng. (2023) Solubility Measurement and Model Correlation of N,N′-Oxalyldiglycine in Eleven Pure Solvents and a Binary Solvent from 293.15 to 333.15 K. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 68 (12): (3423–3434). [PMID:7644499] |
| 4. Zhihui Wang, Yilin Liang, Chenxi Gao, Weiwei Wu, Jiumei Kong, Zhe Zhou, Zhihua Wang, Yan Huang, Weijiang Sun. (2024) The flavor characteristics and antioxidant capability of aged Jinhua white tea and the mechanisms of its dynamic evolution during long-term aging. FOOD CHEMISTRY, 436 (137705). [PMID:37839126] |
| 5. Wenjing Wang, Yumin He, Lei Deng, Hui Wang, Xiaoying Liu, Qing-wen Gui, Zhong Cao, Zemeng Feng, Benhai Xiong, Yulong Yin. (2023) Peptide aptamer-based polyaniline-modified amperometric biosensor for L-lysine detection in real serum samples. MEASUREMENT, 221 (113468). [PMID:] |
| 6. Linjie Guan, Meiyu Liu, Honghai Liu, Li Zhang, Yiming Zhang, Yucai Qin, Binbin He, Yi Mei, Yun Zu. (2023) Regionally spatial framework Al distribution in MFI channels and its impact on the n-butane cracking reaction pathways. FUEL, 353 (129230). [PMID:] |
| 7. Wenting Li, Xinai Zhang, Yongqiang Shi, Xuetao Hu, Xin Wang, Nini Liang, Tingting Shen, Xiaobo Zou, Jiyong Shi. (2023) A dual-modal biosensor coupling cooperative catalysis strategy for sensitive detection of AFB1 in agri-products. FOOD CHEMISTRY, 426 (136553). [PMID:37354581] |
| 8. Xiaoyao Wei, Tao Lin, Le Wang, Jiacheng Lin, Xuefeng Yin. (2023) Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 235 (123805). [PMID:36863669] |
| 9. Guo-Ying Chen, Shi-Jun Yin, Li Chen, Xi Zhou, Feng-Qing Yang. (2022) Nanoporous ZIF-8 Microparticles as Acetylcholinesterase and Alkaline Phosphatase Mimics for the Selective and Sensitive Detection of Ascorbic Acid Oxidase and Copper Ions. Biosensors-Basel, 12 (11): (1049). [PMID:36421167] |
| 10. Qing Hu, Chaofeng Zhu, Wen Yan, Yang Wang, Songlin Cui, Xihai Chen, Bo Liu. (2022) Coordination-Assistant Chiral Agent Anchoring on Amphiphilic Graphitic Phase Carbon Nitride Membrane for Multiple Molecular Separation. ACS Applied Materials & Interfaces, 14 (44): (50235–50245). [PMID:36315245] |
| 11. Li-Jing Peng, Chun-Yan Zhang, Wei-Yi Zhang, Hang-Yu Zhou, Feng-Qing Yang. (2022) The peroxidase-like catalytic activity of in situ prepared cobalt carbonate and its applications in colorimetric detection of hydrogen peroxide, glucose and ascorbic acid. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 651 (129744). [PMID:] |
| 12. Yi Xiao, Guofang Wang, Haomin Yi, Suhua Chen, Qinyu Wu, Siyi Zhang, Kexin Deng, Simeng Zhang, Zi-Qi Shi, Xiaoping Yang. (2022) Electrogenerated chemiluminescence of a Ru(bpy)32+/arginine system: a specific and sensitive detection of acetaminophen. RSC Advances, 12 (5): (3157-3164). [PMID:35425325] |
References
| 1. Ting Gong, Qi Mu, Yongjian Xu, Weiyong Wang, Lijie Meng, Xianzhou Feng, Wenjiao Liu, Zheng Ao, Yiyu Zhang, Xiang Chen, Houqiang Xu. (2023) Expression of the umami taste receptor T1R1/T1R3 in porcine testis of: function in regulating testosterone synthesis and autophagy in Leydig cells. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, (11): (106429). [PMID:38035949] |
| 2. Jierui Yang, Huiting Qiu, Shuang Meng, Yunhui Yang. (2024) A sensing platform for ascorbic acid based on the spatial confinement of covalent organic frameworks. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 308 (19): (123687). [PMID:38042123] |
| 3. Xin Huang, Qiufen Wang, Shouxiang Jiang, Bin Wang, Wenjun Xie, Chengfei Wang, Haoran Li, Guan Wang, Gengxiu Zheng. (2023) Solubility Measurement and Model Correlation of N,N′-Oxalyldiglycine in Eleven Pure Solvents and a Binary Solvent from 293.15 to 333.15 K. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 68 (12): (3423–3434). [PMID:7644499] |
| 4. Zhihui Wang, Yilin Liang, Chenxi Gao, Weiwei Wu, Jiumei Kong, Zhe Zhou, Zhihua Wang, Yan Huang, Weijiang Sun. (2024) The flavor characteristics and antioxidant capability of aged Jinhua white tea and the mechanisms of its dynamic evolution during long-term aging. FOOD CHEMISTRY, 436 (137705). [PMID:37839126] |
| 5. Wenjing Wang, Yumin He, Lei Deng, Hui Wang, Xiaoying Liu, Qing-wen Gui, Zhong Cao, Zemeng Feng, Benhai Xiong, Yulong Yin. (2023) Peptide aptamer-based polyaniline-modified amperometric biosensor for L-lysine detection in real serum samples. MEASUREMENT, 221 (113468). [PMID:] |
| 6. Linjie Guan, Meiyu Liu, Honghai Liu, Li Zhang, Yiming Zhang, Yucai Qin, Binbin He, Yi Mei, Yun Zu. (2023) Regionally spatial framework Al distribution in MFI channels and its impact on the n-butane cracking reaction pathways. FUEL, 353 (129230). [PMID:] |
| 7. Wenting Li, Xinai Zhang, Yongqiang Shi, Xuetao Hu, Xin Wang, Nini Liang, Tingting Shen, Xiaobo Zou, Jiyong Shi. (2023) A dual-modal biosensor coupling cooperative catalysis strategy for sensitive detection of AFB1 in agri-products. FOOD CHEMISTRY, 426 (136553). [PMID:37354581] |
| 8. Xiaoyao Wei, Tao Lin, Le Wang, Jiacheng Lin, Xuefeng Yin. (2023) Research on deep eutectic solvents for the construction of humidity-responsive cellulose nanocrystal composite films. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 235 (123805). [PMID:36863669] |
| 9. Guo-Ying Chen, Shi-Jun Yin, Li Chen, Xi Zhou, Feng-Qing Yang. (2022) Nanoporous ZIF-8 Microparticles as Acetylcholinesterase and Alkaline Phosphatase Mimics for the Selective and Sensitive Detection of Ascorbic Acid Oxidase and Copper Ions. Biosensors-Basel, 12 (11): (1049). [PMID:36421167] |
| 10. Qing Hu, Chaofeng Zhu, Wen Yan, Yang Wang, Songlin Cui, Xihai Chen, Bo Liu. (2022) Coordination-Assistant Chiral Agent Anchoring on Amphiphilic Graphitic Phase Carbon Nitride Membrane for Multiple Molecular Separation. ACS Applied Materials & Interfaces, 14 (44): (50235–50245). [PMID:36315245] |
| 11. Li-Jing Peng, Chun-Yan Zhang, Wei-Yi Zhang, Hang-Yu Zhou, Feng-Qing Yang. (2022) The peroxidase-like catalytic activity of in situ prepared cobalt carbonate and its applications in colorimetric detection of hydrogen peroxide, glucose and ascorbic acid. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 651 (129744). [PMID:] |
| 12. Yi Xiao, Guofang Wang, Haomin Yi, Suhua Chen, Qinyu Wu, Siyi Zhang, Kexin Deng, Simeng Zhang, Zi-Qi Shi, Xiaoping Yang. (2022) Electrogenerated chemiluminescence of a Ru(bpy)32+/arginine system: a specific and sensitive detection of acetaminophen. RSC Advances, 12 (5): (3157-3164). [PMID:35425325] |