Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | L-glutamine | glutamine | 56-85-9 | Levoglutamide | L-(+)-Glutamine | Glutamic acid amide | Cebrogen | Stimulina | (S)-2,5-Diamino-5-oxopentanoic acid | glumin | H-Gln-OH | Levoglutamid | glutamic acid 5-amide | L-Glutamide | 2-aminoglutaramic acid | Glavamin | Miglu-P | Nutrestore | Safori |
|---|---|
| Specifications & Purity | Moligand™, 10mM in Water |
| Biochemical and Physiological Mechanisms | Amino acid. Major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells. Inhibits the generation of L-Arginine by cultured endothelial cells. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Product Description | L-Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. |
Associated Targets(Human)
GPRC6A Tchem G-protein coupled receptor family C group 6 member A (1 Activities)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CA1 Tclin Carbonic anhydrase I (13240 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ARSA Tbio Cerebroside-sulfatase (655 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC1A4 Tbio Neutral amino acid transporter A (18 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Homo sapiens (32628 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
BLM Tchem Bloom syndrome protein (4248 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC1A5 Tchem Neutral amino acid transporter B(0) (65 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Plasmodium falciparum (966862 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Canis familiaris (36305 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
pfk 6-phospho-1-fructokinase (7870 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Grin1 Glutamate NMDA receptor (6467 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Slc1a5 Amino acid transporter (271 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Slc7a10 Asc-type amino acid transporter 1 (14 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Carbonic anhydrase-like protein, putative (25 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | (2S)-2,5-diamino-5-oxopentanoic acid |
|---|---|
| INCHI | InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1 |
| InChi Key | ZDXPYRJPNDTMRX-VKHMYHEASA-N |
| Canonical SMILES | C(CC(=O)N)C(C(=O)O)N |
| Isomeric SMILES | C(CC(=O)N)[C@@H](C(=O)O)N |
| WGK Germany | 1 |
| RTECS | MA2275100 |
| PubChem CID | 5961 |
| Molecular Weight | 146.15 |
| Beilstein | 4491 |
| Reaxy-Rn | 1723797 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Specific Rotation[α] | 6.8 ° (C=4, H2O) |
|---|---|
| Melt Point(°C) | 185-186°C |
Safety and Hazards(GHS)
| WGK Germany | 1 |
|---|---|
| RTECS | MA2275100 |
| Reaxy-Rn | 1723797 |
| Merck Index | 4471 |
Related Documents
FAQs and Articles
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| 2. Qiankun Quan, Xinxin Ma, Ming Li, Xi Li, Haifeng Yuan. (2024) Ginsenoside Rg1 promotes β‑amyloid peptide degradation through inhibition of the ERK/PPARγ phosphorylation pathway in an Alzheimer's disease neuronal model. Experimental and Therapeutic Medicine, 27 (1): (1-13). [PMID:38125359] [10.3892/etm.2023.12319] |
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| 4. Ting Liu, Ling Wang, Yang Yu, Zhuo Zhang, Zelong Duan, Yawen Li, Chencan Li. (2024) Adenosine Triphosphatase-Stabilized ZIF-67 as Peroxidase Mimic for Rapid Detection of Glutathione. INORGANIC CHEMISTRY COMMUNICATIONS, 159 (1): (111705). [PMID:14612514] [10.1016/j.inoche.2023.111705] |
| 5. Lvyuan Fan, Zhiyu Pan, Yilin Zhong, Juan Guo, Xu Liao, Rui Pang, Qingqiang Xu, Guozhu Ye, Yubin Su. (2023) L-glutamine sensitizes Gram-positive-resistant bacteria to gentamicin killing. Microbiology Spectrum, 11 (6): [PMID:37882580] [10.1128/spectrum.01619-23] |
| 6. Pan Jun, Cai Youzhi, Zhang Chi, Xu Sanzhong. (2023) Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation. JOURNAL OF MOLECULAR HISTOLOGY, (1-13). [PMID:37848748] [10.1007/s10735-023-10163-4] |
| 7. Yanan Li, Pingping Dong, Long Dai, Shaoping Wang. (2023) Untargeted and Targeted Metabolomics Reveal the Active Peptide of Eupolyphaga sinensis Walker against Hyperlipidemia by Modulating Imbalance in Amino Acid Metabolism. MOLECULES, 28 (20): (7049). [PMID:37894528] [10.3390/molecules28207049] |
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