Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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L422952-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $36.90 |
Hydrogen acceptor in determination of NADP and NADPH
Synonyms | oxiglutatione | glutathione disulfide | 27025-41-8 | GSSG | Glutathione disulphide | Oxigluthione | Glutathione-ssg | Glutathone disulfide | Bi(glutathion-S-yl) | L(-)-Glutathione | Oxiglutatione [INN] | S,S'-Ethylenebis(glutathione) | Oxiglutationum [INN-Latin] | Oxiglutationa [I |
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Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | Hydrogen acceptor in determination of NADP and NADPH. Marker of oxidative stress. Oxidized form of GSH. Ratio of GSSG:GSH determines redox state of cysteines in some proteins. Active in vivo and in vitro . |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | Amino Acid Sequence Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b] |
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IUPAC Name | (2S)-2-amino-5-[[(2R)-3-[[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid |
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INCHI | InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1 |
InChi Key | YPZRWBKMTBYPTK-BJDJZHNGSA-N |
Canonical SMILES | N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O |
Isomeric SMILES | C(CC(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N)C(=O)NCC(=O)O)[C@@H](C(=O)O)N |
WGK Germany | 2 |
RTECS | MC0556500 |
PubChem CID | 65359 |
Molecular Weight | 612.63 |
Beilstein | 1718700 |
Reaxy-Rn | 8603291 |
Enter Lot Number to search for COA:
Specific Rotation[α] | -105 ° (C=2, H2O) |
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Melt Point(°C) | 178°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | MC0556500 |
Reaxy-Rn | 8603291 |
1. Jia Lin, Guoqing Yue, Kang Xiao, Deqing Yang, Xuxing Hao, Minlin Zheng, Pumo Cai, Qing'e Ji. (2023) Effects of low-concentration spinetoram wax-based bait stations on Bactrocera dorsalis (Diptera: Tephritidae). PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 197 (21): (105705). [PMID:38072558] |
2. Xiaofang Wang, Huiming Wang, Meining Zhang. (2023) A multi-stimuli-responsive nanochannel inspired by biological disulfide bond. TALANTA, 265 (124785). [PMID:37348351] |
3. Luo Gu, Qiuyu Zhu, Xiaoyu Zou, Ru Song. (2023) Antibacterial Effect of Shrimp By-Products Hydrolysate on Specific Spoilage Organisms of Squid. MOLECULES, 28 (10): (4105). [PMID:37241846] |
4. Jia Kong, Jinyao Hu, Jia Li, Jiaxing Zhang, Yuhe Shen, Tianli Yue, Xihui Shen, Yuefei Wang, Zhonghong Li, Yinqiang Xia. (2023) Rethreading Design of Ratiometric roGFP2 Mimetic Peptide for Hydrogen Peroxide Sensing. ANALYTICAL CHEMISTRY, 95 (21): (8284–8290). [PMID:37161261] |
5. Mengfei Liu, Hong Mo, Qingyu Gao, Ling Yuan. (2022) The pH dependence of emulsifying properties for glutathione disulfide at oil-water interfaces. BIOPHYSICAL CHEMISTRY, 282 (106748). [PMID:34959125] |
6. Xiang-Rong Cheng, Piao-Han Tu, Wen-Le Dong, Bu-Tao Yu, Shu-Fang Xia, Mitchell N. Muskat, Bin Guan. (2022) Electrophilic thymol isobutyrate from Inula nervosa Wall. (Xiaoheiyao) ameliorates steatosis in HepG2 cells via Nrf2 activation. Journal of Functional Foods, 88 (104895). [PMID:] |
1. Jia Lin, Guoqing Yue, Kang Xiao, Deqing Yang, Xuxing Hao, Minlin Zheng, Pumo Cai, Qing'e Ji. (2023) Effects of low-concentration spinetoram wax-based bait stations on Bactrocera dorsalis (Diptera: Tephritidae). PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 197 (21): (105705). [PMID:38072558] |
2. Xiaofang Wang, Huiming Wang, Meining Zhang. (2023) A multi-stimuli-responsive nanochannel inspired by biological disulfide bond. TALANTA, 265 (124785). [PMID:37348351] |
3. Luo Gu, Qiuyu Zhu, Xiaoyu Zou, Ru Song. (2023) Antibacterial Effect of Shrimp By-Products Hydrolysate on Specific Spoilage Organisms of Squid. MOLECULES, 28 (10): (4105). [PMID:37241846] |
4. Jia Kong, Jinyao Hu, Jia Li, Jiaxing Zhang, Yuhe Shen, Tianli Yue, Xihui Shen, Yuefei Wang, Zhonghong Li, Yinqiang Xia. (2023) Rethreading Design of Ratiometric roGFP2 Mimetic Peptide for Hydrogen Peroxide Sensing. ANALYTICAL CHEMISTRY, 95 (21): (8284–8290). [PMID:37161261] |
5. Mengfei Liu, Hong Mo, Qingyu Gao, Ling Yuan. (2022) The pH dependence of emulsifying properties for glutathione disulfide at oil-water interfaces. BIOPHYSICAL CHEMISTRY, 282 (106748). [PMID:34959125] |
6. Xiang-Rong Cheng, Piao-Han Tu, Wen-Le Dong, Bu-Tao Yu, Shu-Fang Xia, Mitchell N. Muskat, Bin Guan. (2022) Electrophilic thymol isobutyrate from Inula nervosa Wall. (Xiaoheiyao) ameliorates steatosis in HepG2 cells via Nrf2 activation. Journal of Functional Foods, 88 (104895). [PMID:] |