L-Glutathione oxidized - 10mM in DMSO, high purity , CAS No.27025-41-8

6 Citations
  • 10mM in DMSO
Item Number
L422952
Grouped product items
SKUSizeAvailabilityPrice Qty
L422952-1ml
1ml
Available within 8-12 weeks(?)
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$36.90

Hydrogen acceptor in determination of NADP and NADPH

Basic Description

Synonymsoxiglutatione | glutathione disulfide | 27025-41-8 | GSSG | Glutathione disulphide | Oxigluthione | Glutathione-ssg | Glutathone disulfide | Bi(glutathion-S-yl) | L(-)-Glutathione | Oxiglutatione [INN] | S,S'-Ethylenebis(glutathione) | Oxiglutationum [INN-Latin] | Oxiglutationa [I
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsHydrogen acceptor in determination of NADP and NADPH. Marker of oxidative stress. Oxidized form of GSH. Ratio of GSSG:GSH determines redox state of cysteines in some proteins. Active in vivo and in vitro .
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Amino Acid Sequence Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]
The oxidised dimeric form of glutathione that takes part in the body’s detoxification mechanisms

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcc1 Multidrug resistance-associated protein 1 (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Helicobacter pylori (3113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glra2 Glycine receptor (1745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S)-2-amino-5-[[(2R)-3-[[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
INCHI InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1
InChi Key YPZRWBKMTBYPTK-BJDJZHNGSA-N
Canonical SMILES N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O
Isomeric SMILES C(CC(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N)C(=O)NCC(=O)O)[C@@H](C(=O)O)N
WGK Germany 2
RTECS MC0556500
PubChem CID 65359
Molecular Weight 612.63
Beilstein 1718700
Reaxy-Rn 8603291

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]-105 ° (C=2, H2O)
Melt Point(°C)178°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS MC0556500
Reaxy-Rn 8603291

Related Documents

Citations of This Product

1. Jia Lin, Guoqing Yue, Kang Xiao, Deqing Yang, Xuxing Hao, Minlin Zheng, Pumo Cai, Qing'e Ji.  (2023)  Effects of low-concentration spinetoram wax-based bait stations on Bactrocera dorsalis (Diptera: Tephritidae).  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,  197  (21): (105705).  [PMID:38072558]
2. Xiaofang Wang, Huiming Wang, Meining Zhang.  (2023)  A multi-stimuli-responsive nanochannel inspired by biological disulfide bond.  TALANTA,  265  (124785).  [PMID:37348351]
3. Luo Gu, Qiuyu Zhu, Xiaoyu Zou, Ru Song.  (2023)  Antibacterial Effect of Shrimp By-Products Hydrolysate on Specific Spoilage Organisms of Squid.  MOLECULES,  28  (10): (4105).  [PMID:37241846]
4. Jia Kong, Jinyao Hu, Jia Li, Jiaxing Zhang, Yuhe Shen, Tianli Yue, Xihui Shen, Yuefei Wang, Zhonghong Li, Yinqiang Xia.  (2023)  Rethreading Design of Ratiometric roGFP2 Mimetic Peptide for Hydrogen Peroxide Sensing.  ANALYTICAL CHEMISTRY,  95  (21): (8284–8290).  [PMID:37161261]
5. Mengfei Liu, Hong Mo, Qingyu Gao, Ling Yuan.  (2022)  The pH dependence of emulsifying properties for glutathione disulfide at oil-water interfaces.  BIOPHYSICAL CHEMISTRY,  282  (106748).  [PMID:34959125]
6. Xiang-Rong Cheng, Piao-Han Tu, Wen-Le Dong, Bu-Tao Yu, Shu-Fang Xia, Mitchell N. Muskat, Bin Guan.  (2022)  Electrophilic thymol isobutyrate from Inula nervosa Wall. (Xiaoheiyao) ameliorates steatosis in HepG2 cells via Nrf2 activation.  Journal of Functional Foods,  88  (104895).  [PMID:]

References

1. Jia Lin, Guoqing Yue, Kang Xiao, Deqing Yang, Xuxing Hao, Minlin Zheng, Pumo Cai, Qing'e Ji.  (2023)  Effects of low-concentration spinetoram wax-based bait stations on Bactrocera dorsalis (Diptera: Tephritidae).  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,  197  (21): (105705).  [PMID:38072558]
2. Xiaofang Wang, Huiming Wang, Meining Zhang.  (2023)  A multi-stimuli-responsive nanochannel inspired by biological disulfide bond.  TALANTA,  265  (124785).  [PMID:37348351]
3. Luo Gu, Qiuyu Zhu, Xiaoyu Zou, Ru Song.  (2023)  Antibacterial Effect of Shrimp By-Products Hydrolysate on Specific Spoilage Organisms of Squid.  MOLECULES,  28  (10): (4105).  [PMID:37241846]
4. Jia Kong, Jinyao Hu, Jia Li, Jiaxing Zhang, Yuhe Shen, Tianli Yue, Xihui Shen, Yuefei Wang, Zhonghong Li, Yinqiang Xia.  (2023)  Rethreading Design of Ratiometric roGFP2 Mimetic Peptide for Hydrogen Peroxide Sensing.  ANALYTICAL CHEMISTRY,  95  (21): (8284–8290).  [PMID:37161261]
5. Mengfei Liu, Hong Mo, Qingyu Gao, Ling Yuan.  (2022)  The pH dependence of emulsifying properties for glutathione disulfide at oil-water interfaces.  BIOPHYSICAL CHEMISTRY,  282  (106748).  [PMID:34959125]
6. Xiang-Rong Cheng, Piao-Han Tu, Wen-Le Dong, Bu-Tao Yu, Shu-Fang Xia, Mitchell N. Muskat, Bin Guan.  (2022)  Electrophilic thymol isobutyrate from Inula nervosa Wall. (Xiaoheiyao) ameliorates steatosis in HepG2 cells via Nrf2 activation.  Journal of Functional Foods,  88  (104895).  [PMID:]

Solution Calculators