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L-Isoleucine - 10mM in Water, high purity , CAS No.73-32-5

59 Citations
  • CAS#:  73-32-5
  • Formula:   C6H13NO2
  • Molecular Weight:  131.18
  • Beilstein Registry Number:   4454
  • PubChem CID:   6306
Item Number
L425728
Grouped product items
SKUSizeAvailabilityPrice Qty
L425728-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$36.90
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Basic Description

Synonymsl-isoleucine | Isoleucine | 73-32-5 | (2S,3S)-2-Amino-3-methylpentanoic acid | 2S,3S-Isoleucine | (S)-Isoleucine | H-Ile-OH | (S,S)-Isoleucine | 2-Amino-3-methylvaleric acid | L-(+)-Isoleucine | erythro-L-Isoleucine | L-Ile | ISOLEUCINE, L- | alpha-Amino-beta-methylvaleric acid | Is
Specifications & PurityMoligand™, 10mM in Water
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™

Associated Targets(Human)

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PKM Tchem Pyruvate kinase PKM (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC16A10 Tbio Monocarboxylate transporter 10 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC7A5 Tchem Large neutral amino acids transporter small subunit 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S,3S)-2-amino-3-methylpentanoic acid
INCHI InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
InChi Key AGPKZVBTJJNPAG-WHFBIAKZSA-N
Canonical SMILES CCC(C)C(C(=O)O)N
Isomeric SMILES CC[C@H](C)[C@@H](C(=O)O)N
RTECS NR4705000
PubChem CID 6306
Molecular Weight 131.18
Beilstein 4454
Reaxy-Rn 1721792

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]40.5 ° (C=4, 6mol/L HCl)
Melt Point(°C)288 °C

Safety and Hazards(GHS)

RTECS NR4705000
Reaxy-Rn 1721792
Merck Index 5179

Related Documents

 SDS

 Specification Sheet

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Zhiyang Xu, Yinzhou Yan, Xingyuan Wang, Xiaolei Wang, Zhixiang Zhou, Xi Yang, Tianrui Zhai.  (2023)  Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point.  Advanced Science,    (2308362).  [PMID:38072636] [10.1002/advs.202308362]
2. Zhen Lin, Chuangui Cai, Wei Chen, Qian Deng, Jialin Yang, Kaiyuan Huang, Haohua Deng, Xinhua Lin, Wei Chen, Wensong Yao.  (2024)  Micelle-mediated chemiluminescence of 6-aza-2-thiothymine-protected gold nanoclusters for carbazochrome sodium sulfonate detection.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  308  (123738).  [PMID:38086230] [10.1016/j.saa.2023.123738]
3. Wei Jia, Jiying Zhu.  (2023)  Molecular Mechanism of ε-Polylysine Treatment of Animal-Derived Foods: Glycine Amidinotransferase Activity Implicates Upregulation of l-Arginine and Creatine.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  71  (41): (15106–15120).  [PMID:37793042] [10.1021/acs.jafc.3c04033]
4. Jierui Yang, Benqi Chen, Huiting Qiu, Shuang Meng, Yunhui Yang.  (2023)  Ni3V2O8 nanoflower mimetic enzyme constructs a dual-signal system for ascorbic acid detection.  RSC Advances,  13  (37): (26102-26110).  [PMID:37664210] [10.1039/D3RA04202B]
5. Wenjing Wang, Yumin He, Lei Deng, Hui Wang, Xiaoying Liu, Qing-wen Gui, Zhong Cao, Zemeng Feng, Benhai Xiong, Yulong Yin.  (2023)  Peptide aptamer-based polyaniline-modified amperometric biosensor for L-lysine detection in real serum samples.  MEASUREMENT,  221  (113468).  [PMID:] [10.1016/j.measurement.2023.113468]
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7. Yichen Wang, Renjin Zheng, Pingping Wu, Youjia Wu, Lingyi Huang, Liying Huang.  (2023)  Determination of Multiple Neurotransmitters through LC-MS/MS to Confirm the Therapeutic Effects of Althaea rosea Flower on TTX-Intoxicated Rats.  MOLECULES,  28  (10): (4158).  [PMID:37241898] [10.3390/molecules28104158]
8. Chonghui Wei, Xuan Xie, Yue Mou, Shiqi Cheng, Jin Yang, Kaixin Xue, Kewei Yu, Xinru Lin, Chunfen Zhang, Yujie Zhao, Xingyu Luo, Yilin Wang.  (2023)  Controllable synthesis of MoS2@TiO2 nanocomposites for visual detection of dopamine secretion with highly-efficient enzymatic activity.  ANALYST,  148  (8): (1732-1742).  [PMID:36938870] [10.1039/D3AN00089C]
9. Yankui Xing, Zhengda Zhou, Fangfang Li, Shuangping Tian, Yuxi Liang, Sixian Li, Yanan Zhou, Yun Gao.  (2023)  Solid-liquid equilibrium and dissolution thermodynamic properties of L-isoleucine in binary solvent mixtures.  JOURNAL OF CHEMICAL THERMODYNAMICS,  182  (107035).  [PMID:] [10.1016/j.jct.2023.107035]
10. Chengxiang Chu, Xianfeng Wang, Yuanyi Deng, Yi Ma, Chengyue Zou, Mei Yang, Huibo Luo, Danqun Huo, Changjun Hou.  (2023)  Discrimination of Chinese green tea according to tea polyphenols using fluorescence sensor array based on Tb (III) and Eu (III) doped Zr (IV) metal–organic frameworks.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  292  (122380).  [PMID:36736046] [10.1016/j.saa.2023.122380]
11. Zhang Jing, Yang Junqing, Luo Ying, Li Jiansha, Gong Tao, Huang Suqiong, Xiong Yan, Jiang Xinhui.  (2022)  Determination of 23 Amino Acids and Amines in Plasma and Cortex of C57BL/6 Mice with HPLC–FLD.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,      [PMID:36572394] [10.1093/chromsci/bmac103]
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15. Lin Yuan, Lei Jiang, Ze Liu, Yingying Xiang, Fei Song, Yujiao Tu.  (2023)  Selective and sensitive simultaneous detection of tartrazine and Hg2+ based on N-doped yellow-green fluorescent carbon dots.  DYES AND PIGMENTS,  209  (110893).  [PMID:] [10.1016/j.dyepig.2022.110893]
16. Hui Yuan, Yu Chen, Ruikang Lin, Dan Tan, Jiaojiao Zhang, Yongmei Wang, Ehud Gazit, Wei Ji, Rusen Yang.  (2022)  Modified Stranski–Krastanov Growth of Amino Acid Arrays toward Piezoelectric Energy Harvesting.  ACS Applied Materials & Interfaces,  14  (41): (46304–46312).  [PMID:36196653] [10.1021/acsami.2c13399]
17. Hang Zhang, Jun Jiang Luo, Zhe Sun, Hao Lin Zou, Hong Qun Luo, Nian Bing Li, Bang Lin Li.  (2022)  Hydrogels allow the precise growth tracking of plasmonic gold nanoparticles for mercury analysis.  Journal of Materials Chemistry C,  10  (39): (14508-14516).  [PMID:] [10.1039/D2TC02483G]
18. Hai-Bin Qin, Jun-Ping Zhou, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng.  (2022)  Combing with redox regulation via quorum-sensing system and fermentation strategies for improving D-pantothenic acid production.  PROCESS BIOCHEMISTRY,  121  (681).  [PMID:] [10.1016/j.procbio.2022.08.012]
19. Yingying Xiang, Yujiao Tu, Lei Jiang, Lin Yuan, Ze Liu, Qiang Xie, Xuequan Xiong, Fei Song.  (2022)  Orange fluorescent dual-mode nanoprobe for selective and sensitive detection of amaranth based on S,N-Doped carbon dots.  DYES AND PIGMENTS,  205  (110533).  [PMID:] [10.1016/j.dyepig.2022.110533]
20. Wenjing Wang, Yumin He, Yunling Gao, Hongrui Gao, Lei Deng, Qingwen Gui, Zhong Cao, Yulong Yin, Zemeng Feng.  (2022)  A peptide aptamer based electrochemical amperometric sensor for sensitive L-glutamate detection.  BIOELECTROCHEMISTRY,  146  (108165).  [PMID:35623273] [10.1016/j.bioelechem.2022.108165]
21. Ling Li, Miaomiao Zhang, Ran Li, Huan Jiang, Zhongde Liu.  (2021)  Facile synthesis of highly luminescent rod-like terbium-based metal–organic frameworks for sensitive detection of olaquindox.  Analytical Methods,  13  (34): (3785-3791).  [PMID:34350907] [10.1039/D1AY00824B]
22. Bo Zhang, Li Chen, Jie-Yi Jin, Na Zhong, Xue Cai, Shu-Ping Zou, Hai-Yan Zhou, Zhi-Qiang Liu, Yu-Guo Zheng.  (2021)  Strengthening the (R)-pantoate pathway to produce D-pantothenic acid based on systematic metabolic analysis.  Food Bioscience,  43  (101283).  [PMID:] [10.1016/j.fbio.2021.101283]
23. Jing Zhang, Xinxin Wen, Yuting Li, Jing Zhang, Xian Li, Cheng Qian, Yonghui Tian, Rui Ling, Yixiang Duan.  (2021)  Diagnostic approach to thyroid cancer based on amino acid metabolomics in saliva by ultra-performance liquid chromatography with high resolution mass spectrometry.  TALANTA,  235  (122729).  [PMID:34517597] [10.1016/j.talanta.2021.122729]
24. Lili Zhu, Jun Dong, Qunfeng Zeng, Mianran Chao, Kuiliang Gong, Weimin Li, Xiaobo Wang.  (2021)  A comprehensive study of amino acids based ionic liquids as green lubricants for various contacts.  TRIBOLOGY INTERNATIONAL,  162  (107137).  [PMID:] [10.1016/j.triboint.2021.107137]
25. Pengpeng Zhang, Shuai Liu, Shuang Yang, Yuanhong Wang, Tingfu Jiang, Mingming Yu, Zhihua Lv.  (2021)  Simultaneous determination of chito-oligosaccharides in rat plasma by the LC-MS/MS method: application to a pharmacokinetic study.  Analytical Methods,  13  (29): (3242-3248).  [PMID:34184005] [10.1039/D1AY00772F]
26. Bochuan Yuan, Ziwei Wu, Wei Ji, Dong Liu, Xiang Guo, Donghui Yang, Aili Fan, Hongli Jia, Ming Ma, Wenhan Lin.  (2021)  Discovery of cyclohexadepsipeptides with anti-Zika virus activities and biosynthesis of the nonproteinogenic building block (3S)-methyl-l-proline.  JOURNAL OF BIOLOGICAL CHEMISTRY,  297  (1):   [PMID:34029593] [10.1016/j.jbc.2021.100822]
27. Lamei Yang, Feng Luo, Weili Wei.  (2021)  Simultaneous determination of the concentration and enantiomeric excess of amino acids with a coumarin-derived achiral probe.  Analytical Methods,  13  (16): (1905-1910).  [PMID:33913945] [10.1039/D1AY00271F]
28. Yuanyuan Zhang, Hedan Xu, Yuling Yang, Fengmei Zhu, Yunxun Pu, Xiaoshuang You, Xiaoling Liao.  (2021)  Efficient fluorescence resonance energy transfer-based ratiometric fluorescent probe for detection of dopamine using a dual-emission carbon dot-gold nanocluster nanohybrid.  JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,  411  (113195).  [PMID:] [10.1016/j.jphotochem.2021.113195]
29. Xinying Wang, Ming Gao, Zihan Wang, Weiqi Cui, Jingxian Zhang, Weijie Zhang, Yu Xia, Bo Wei, Youcai Tang, Xia Xu.  (2021)  Hepatoprotective effects of oridonin against bisphenol A induced liver injury in rats via inhibiting the activity of xanthione oxidase.  SCIENCE OF THE TOTAL ENVIRONMENT,  770  (145301).  [PMID:33515877] [10.1016/j.scitotenv.2021.145301]
30. Chengxiang Chu, Rui Huang, Xianfeng Wang, Yuanyi Deng, Tao Gu, Danqun Huo, Liang Zhang, Daidi Zhong, Changjun Hou.  (2021)  A Turn-on Fluorescent Sensor Based on Copper-Based Metal-Organic Frameworks for Sensitive Detection of L-Histidine.  NANO,      [PMID:] [10.1142/S1793292021500156]
31. Yumin He, Li Zhou, Lei Deng, Zemeng Feng, Zhong Cao, Yulong Yin.  (2021)  An electrochemical impedimetric sensing platform based on a peptide aptamer identified by high-throughput molecular docking for sensitive l-arginine detection.  BIOELECTROCHEMISTRY,  137  (107634).  [PMID:32882443] [10.1016/j.bioelechem.2020.107634]
32. Yuanyuan Zhang, Mei Yang, Zeyu Shao, Hedan Xu, Yan Chen, Yuling Yang, Wenfeng Xu, Xiaoling Liao.  (2020)  A paper-based fluorescent test for determination and visualization of cysteine and glutathione by using gold-silver nanoclusters.  MICROCHEMICAL JOURNAL,  158  (105327).  [PMID:] [10.1016/j.microc.2020.105327]
33. Yujiao Tu, Xuemei Chen, Yingying Xiang, Xiaotian Yuan, Kunhao Qin, Yunlin Wei, Zhiwei Xu, Qi Zhang, Xiuling Ji.  (2020)  Hydrothermal Synthesis of a Novel Mesoporous Silica Fluorescence Carbon Dots and Application in Cr(VI) and Folic Acid Detection.  NANO,      [PMID:] [10.1142/S1793292020500903]
34. Lijuan Huang, Liyun Wang, Zhiyong Nie, Yongan Wang.  (2020)  Simultaneous quantitative measurements of Tl+ and Pb2+ in drinking water based on nanoplasmonic probe.  FOOD CHEMISTRY,  319  (126543).  [PMID:32146290] [10.1016/j.foodchem.2020.126543]
35. Zhixiong Hu, Xin-Yue Jiao, Li Xu.  (2020)  The N,S co-doped carbon dots with excellent luminescent properties from green tea leaf residue and its sensing of gefitinib.  MICROCHEMICAL JOURNAL,  154  (104588).  [PMID:] [10.1016/j.microc.2019.104588]
36. Li Te, Xie Lianwu, Long Ruiqing, Tong Chaoying, Guo Ying, Tong Xia, Shi Shuyun, Lin Qinlu.  (2019)  Cetyltrimethyl ammonium mediated enhancement of the red emission of carbon dots and an advanced method for fluorometric determination of iron(III).  MICROCHIMICA ACTA,  186  (12): (1-8).  [PMID:31734753] [10.1007/s00604-019-3933-4]
37. Fei Qu, Qianqian Yang, Bingjie Wang, Jinmao You.  (2020)  Aggregation-induced emission of copper nanoclusters triggered by synergistic effect of dual metal ions and the application in the detection of H2O2 and related biomolecules.  TALANTA,  207  (120289).  [PMID:31594584] [10.1016/j.talanta.2019.120289]
38. Xue-Mei Han, Yan-Jie Qin, Ying Zhu, Xin-Lin Zhang, Nan-Xi Wang, Ying Rang, Xue-Jia Zhai, Yong-Ning Lu.  (2019)  Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  174  (683).  [PMID:31288191] [10.1016/j.jpba.2019.06.043]
39. Renjie Hui, Yueying Gao, Jingyi Liu, Haili Liu, Chunlei Tang, Bainian Feng.  (2019)  Determination of an isonicotinylhydrazide derivative, a novel positive inotropic compound, in mouse plasma by LC–MS/MS and its application to a pharmacokinetics study.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  165  (12).  [PMID:30496986] [10.1016/j.jpba.2018.10.034]
40. Jie Yang, Zhongming Huang, Yalei Hu, Jia Ge, Jianjun Li, Zhaohui Li.  (2018)  A facile fluorescence assay for rapid and sensitive detection of uric acid based on carbon dots and MnO2 nanosheets.  NEW JOURNAL OF CHEMISTRY,  42  (18): (15121-15126).  [PMID:] [10.1039/C8NJ02607F]
41. Dan Huang, Qing-Song Jiang, Jun-Qing Yang, Ting Cui, Nian-Ru Wang, Ting-Ting Du, Xin-Hui Jiang.  (2018)  Simultaneous determination of nine analytes related to the pathogenesis of diabetic encephalopathy in diabetic rat cortex and hippocampus by HPLC-FLD.  BIOMEDICAL CHROMATOGRAPHY,  32  (11): (e4338).  [PMID:30003560] [10.1002/bmc.4338]
42. Xinru Wang, Dezhen Wang, Zhiqiang Zhou, Wentao Zhu.  (2018)  Subacute oral toxicity assessment of benalaxyl in mice based on metabolomics methods.  CHEMOSPHERE,  191  (373).  [PMID:29054078] [10.1016/j.chemosphere.2017.10.085]
43. Xu Hui-Huang, Deng Hao-Hua, Lin Xiao-Qing, Wu Yan-Yu, Lin Xiu-Ling, Peng Hua-Ping, Liu Ai-Lin, Xia Xing-Hua, Chen Wei.  (2017)  Colorimetric glutathione assay based on the peroxidase-like activity of a nanocomposite consisting of platinum nanoparticles and graphene oxide.  MICROCHIMICA ACTA,  184  (10): (3945-3951).  [PMID:] [10.1007/s00604-017-2429-3]
44. Fuchen Zhang, Qiuxia Wang, Lipeng Wang, Yongping Bai.  (2017)  Implementing plant-derived isosorbide and isomannide as comonomers for polyester synthesis: Effects of crystallization properties on optical properties.  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (43): (45444).  [PMID:] [10.1002/app.45444]
45. Zhijiao Tang, Zhenhua Lin, Gongke Li, Yuling Hu.  (2017)  Amino Nitrogen Quantum Dots-Based Nanoprobe for Fluorescence Detection and Imaging of Cysteine in Biological Samples.  ANALYTICAL CHEMISTRY,  89  (7): (4238–4245).  [PMID:28266840] [10.1021/acs.analchem.7b00284]
46. Jing Liu, Lingjie Meng, Zhaofu Fei, Paul J. Dyson, Xunan Jing, Xing Liu.  (2017)  MnO2 nanosheets as an artificial enzyme to mimic oxidase for rapid and sensitive detection of glutathione.  BIOSENSORS & BIOELECTRONICS,  90  (69).  [PMID:27886603] [10.1016/j.bios.2016.11.046]
47. Zuguang Shen, Guocheng Han, Chuanfu Liu, Xiaoying Wang, Runcang Sun.  (2016)  Green synthesis of silver nanoparticles with bagasse for colorimetric detection of cysteine in serum samples.  JOURNAL OF ALLOYS AND COMPOUNDS,  686  (82).  [PMID:] [10.1016/j.jallcom.2016.05.348]
48. Xiangyu Jiang, Fenghua Geng, Yongxiang Wang, Jinhua Liu, Peng Qu, Maotian Xu.  (2016)  Fluorescence turn-on and colorimetric dual readout assay of glutathione over cysteine based on the fluorescence inner-filter effect of oxidized TMB on TMPyP.  BIOSENSORS & BIOELECTRONICS,  81  (268).  [PMID:26971272] [10.1016/j.bios.2016.02.068]
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55. Qiuxiang Wu, Zhizhou Yang, Jinshui Yao, Donghong Yu.  (2015)  Synthesis and biodegradation studies of optically active poly(amide–imide)s based on N,N′-(pyromellitoyl)-bis-l-amino acid.  HIGH PERFORMANCE POLYMERS,      [PMID:] [10.1177/0954008315569251]
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57. Juan Lv, Li Zhang, Musammir Khan, Xiangkui Ren, Jintang Guo, Yakai Feng.  (2014)  Biodegradable depsipeptide–PDO–PEG-based block copolymer micelles as nanocarriers for controlled release of doxorubicin.  REACTIVE & FUNCTIONAL POLYMERS,  82  (89).  [PMID:] [10.1016/j.reactfunctpolym.2014.06.005]
58. Bixia Huang,Xuewen Hu,Jiancheng Wang,Ping Li,Jun Chen.  (2019-04-29)  Study on chemical constituents of herbal formula Er Miao Wan and GC-MS based metabolomics approach to evaluate its therapeutic effects on hyperuricemic rats..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  1118-1119  (101-108).  [PMID:31030102]
59. Zhang E, Bai PY, Cui DY, Chu WC, Hua YG, Liu Q, Yin HY, Zhang YJ, Qin S, Liu HM..  (2018)  Synthesis and bioactivities study of new antibacterial peptide mimics: The dialkyl cationic amphiphiles..  Eur J Med Chem,  143  (1489-1509).  [PMID:29126736] [10.1016/j.ejmech.2017.10.044]

References

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