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L-Methionine - 99%, high purity , CAS No.63-68-3

63 Citations
Item Number
M101130
Grouped product items
SKUSizeAvailabilityPrice Qty
M101130-25g
25g
In stock
$19.90
M101130-100g
100g
In stock
$45.90
M101130-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$142.90
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Chemical Biology Endogenous Metabolite Metabolic Enzyme/Protease Peptide chemistry

Basic Description

SynonymsH-Met-OH | (35S)Methionine | carbon-11 methionine | L-2-Amino-4methylthiobutyric acid | METHIONINE [II] | L-Methionin | L-Methionine-34S | L-Methioninum | 1pg2 | Methionine [USAN:USP:INN:BAN] | MFCD00063097 | (2S)-2-amino-4-(methylsulfanyl)butanoic acid |
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsMethionine is an essential amino acid which acts a precursor for transmethylation and transsulphuration. In proteins, L-methionine is the biologically active form.The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), w
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
GradeMoligand™
Product Description

L-Methionine is an essential amino acid for human development, hepatoprotectant, acetominophen poisoning antidote, and urinary acidifier.
An essential amino acid


Application:

L-Methionine is used as an essential amino acid for human development and therapeutically acts as an antidote for acetaminophen poisoning. It serves as a chelating agent for heavy metals, as a flavoring agent and nutritional supplement for foods. It acts as a feed additive, vegetable oil enrichment and as a single cell protein. In addition to this, it is used as a hepatoprotectant and also acts as a lipotropic agent and prevents excess fat buildup in the liver.

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FASN Tchem Fatty acid synthase (3390 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mat1a S-adenosylmethionine synthetase alpha and beta forms (31 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mat2a S-adenosylmethionine synthetase gamma form (83 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ggt1 Gamma-glutamyltranspeptidase 1 (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pyricularia grisea (1253 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryza sativa (2923 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
luxS S-ribosylhomocysteine lyase (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mat1a S-adenosylmethionine synthetase (MAT 1 and MAT 2) (155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc1a5 Amino acid transporter (271 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180013
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180013
IUPAC Name (2S)-2-amino-4-methylsulfanylbutanoic acid
INCHI InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChi Key FFEARJCKVFRZRR-BYPYZUCNSA-N
Canonical SMILES CSCC[C@H](N)C(O)=O
Isomeric SMILES CSCC[C@@H](C(=O)O)N
WGK Germany 1
RTECS PD0457000
Molecular Weight 149.21
Beilstein 1722294
Reaxy-Rn 1722294

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

32 results found

Lot NumberCertificate TypeDateItem
K2415556Certificate of AnalysisJul 09, 2024 M101130
E2420305Certificate of AnalysisApr 19, 2024 M101130
E2420306Certificate of AnalysisApr 19, 2024 M101130
E2420307Certificate of AnalysisApr 19, 2024 M101130
D2411296Certificate of AnalysisApr 17, 2024 M101130
D2411297Certificate of AnalysisApr 17, 2024 M101130
D2411298Certificate of AnalysisApr 17, 2024 M101130
J2331554Certificate of AnalysisOct 18, 2023 M101130
J2331553Certificate of AnalysisOct 18, 2023 M101130
J2331552Certificate of AnalysisOct 18, 2023 M101130
J2331551Certificate of AnalysisOct 18, 2023 M101130
D2409045Certificate of AnalysisOct 18, 2023 M101130
F2310318Certificate of AnalysisJul 04, 2023 M101130
F2310317Certificate of AnalysisJul 04, 2023 M101130
F2310314Certificate of AnalysisJul 04, 2023 M101130
G2315296Certificate of AnalysisJun 29, 2023 M101130
G2315300Certificate of AnalysisJun 29, 2023 M101130
G2315924Certificate of AnalysisJun 29, 2023 M101130
G2315931Certificate of AnalysisJun 29, 2023 M101130
G2315932Certificate of AnalysisJun 29, 2023 M101130
K2414184Certificate of AnalysisJun 29, 2023 M101130
D2419030Certificate of AnalysisDec 08, 2022 M101130
B2309430Certificate of AnalysisDec 08, 2022 M101130
B2309455Certificate of AnalysisDec 08, 2022 M101130
B2309458Certificate of AnalysisDec 08, 2022 M101130
B2309460Certificate of AnalysisDec 08, 2022 M101130
B2309463Certificate of AnalysisDec 08, 2022 M101130
B2309423Certificate of AnalysisDec 08, 2022 M101130
H2217440Certificate of AnalysisJul 04, 2022 M101130
H2217438Certificate of AnalysisJul 04, 2022 M101130
H2217416Certificate of AnalysisJul 04, 2022 M101130
H2217415Certificate of AnalysisJul 04, 2022 M101130

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Chemical and Physical Properties

SolubilitySoluble in 1M HCl (50 mg/ml), and water (56.6 mg/ml at 25 °C). Insoluble in ethanol, acetone, and ether.
SensitivityLight & Air sensitive.
Specific Rotation[α]24° (C=8,HCl (1+1))
Melt Point(°C)280-282°C

Safety and Hazards(GHS)

Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

WGK Germany 1
RTECS PD0457000
Reaxy-Rn 1722294
Merck Index 5975

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