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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | norepinephrine|noradrenaline|L-Noradrenaline|51-41-2|Levarterenol|Arterenol|(R)-Noradrenaline|Levophed|(-)-Norepinephrine|L-Norepinephrine|(-)-NORADRENALINE|(R)-Norepinephrine|Aktamin|Levonor|L-arterenol|Levonoradrenaline|4-[(1R)-2-amino-1-hydroxyethyl]be |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Product Description | An adrenergic neurotransmitter. |
Associated Targets
CYP1B1 Tchem Cytochrome P450 1B1 0 Activities
CNR1 Tclin Cannabinoid receptor 1 0 Activities
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DRD2 Tclin D(2) dopamine receptor 0 Activities
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ESR1 Tclin Estrogen receptor 0 Activities
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GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities
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NR3C1 Tclin Glucocorticoid receptor 0 Activities
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POLH Tchem DNA polymerase eta 0 Activities
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AVPR1A Tclin Vasopressin V1a receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HDAC6 Tclin Histone deacetylase 6 0 Activities
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HRH1 Tclin Histamine H1 receptor 0 Activities
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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DRD3 Tclin D(3) dopamine receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADRA2B Tclin Alpha-2B adrenergic receptor 3 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADRA2C Tclin Alpha-2C adrenergic receptor 1 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADORA2A Tclin Adenosine receptor A2a 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADRA1B Tclin Alpha-1B adrenergic receptor 1 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities
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ADRA2A Tclin Alpha-2A adrenergic receptor 1 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities
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ADRA1A Tclin Alpha-1A adrenergic receptor 2 Activities
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AR Tclin Androgen receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities
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HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADORA1 Tclin Adenosine receptor A1 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADORA3 Tchem Adenosine receptor A3 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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OPRD1 Tclin Delta-type opioid receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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OPRK1 Tclin Kappa-type opioid receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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OPRM1 Tclin Mu-type opioid receptor 0 Activities
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MLNR Tchem Motilin receptor 0 Activities
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Names and Identifiers
| IUPAC Name | 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol |
|---|---|
| INCHI | InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1 |
| InChi Key | SFLSHLFXELFNJZ-QMMMGPOBSA-N |
| Canonical SMILES | C1=CC(=C(C=C1C(CN)O)O)O |
| Isomeric SMILES | C1=CC(=C(C=C1[C@H](CN)O)O)O |
| WGK Germany | 3 |
| RTECS | DN5950000 |
| PubChem CID | 439260 |
| UN Number | 2811 |
| Molecular Weight | 169.18 |
| Beilstein | 2804840 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Sensitivity | Air & Light Sensitive |
|---|---|
| Melt Point(°C) | 100-106°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS06 |
|---|---|
| Signal | Danger |
| Hazard Statements | H300:Fatal if swallowed H310:Fatal in contact with skin H330:Fatal if inhaled |
| Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. |
| WGK Germany | 3 |
| RTECS | DN5950000 |